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Items: 12


The Ras/Raf/MEK/ERK signaling pathway and its role in the occurrence and development of HCC.

Li L, Zhao GD, Shi Z, Qi LL, Zhou LY, Fu ZX.

Oncol Lett. 2016 Nov;12(5):3045-3050. Epub 2016 Sep 9.


Mechanisms involved in glucocorticoid induction of pituitary GH expression during embryonic development.

Ellestad LE, Puckett SA, Porter TE.

Endocrinology. 2015 Mar;156(3):1066-79. doi: 10.1210/en.2014-1686. Epub 2015 Jan 5.


PI3K/PTEN signaling in angiogenesis and tumorigenesis.

Jiang BH, Liu LZ.

Adv Cancer Res. 2009;102:19-65. doi: 10.1016/S0065-230X(09)02002-8. Review.


Protein kinase C delta is required for survival of cells expressing activated p21RAS.

Xia S, Forman LW, Faller DV.

J Biol Chem. 2007 May 4;282(18):13199-210. Epub 2007 Mar 8.


Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance.

McCubrey JA, Steelman LS, Chappell WH, Abrams SL, Wong EW, Chang F, Lehmann B, Terrian DM, Milella M, Tafuri A, Stivala F, Libra M, Basecke J, Evangelisti C, Martelli AM, Franklin RA.

Biochim Biophys Acta. 2007 Aug;1773(8):1263-84. Epub 2006 Oct 7. Review.


Differential regulation of B-raf isoforms by phosphorylation and autoinhibitory mechanisms.

Hmitou I, Druillennec S, Valluet A, Peyssonnaux C, Eychène A.

Mol Cell Biol. 2007 Jan;27(1):31-43. Epub 2006 Oct 30.


Ras activity regulates cyclin E degradation by the Fbw7 pathway.

Minella AC, Welcker M, Clurman BE.

Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9649-54. Epub 2005 Jun 24.


A Raf-1 mutant that dissociates MEK/extracellular signal-regulated kinase activation from malignant transformation and differentiation but not proliferation.

Dhillon AS, Meikle S, Peyssonnaux C, Grindlay J, Kaiser C, Steen H, Shaw PE, Mischak H, Eychène A, Kolch W.

Mol Cell Biol. 2003 Mar;23(6):1983-93.


The RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins.

Wang Y, Waldron RT, Dhaka A, Patel A, Riley MM, Rozengurt E, Colicelli J.

Mol Cell Biol. 2002 Feb;22(3):916-26.


Phosphorylation of MafA is essential for its transcriptional and biological properties.

Benkhelifa S, Provot S, Nabais E, Eychène A, Calothy G, Felder-Schmittbuhl MP.

Mol Cell Biol. 2001 Jul;21(14):4441-52.

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