Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 26


Synergistic effects of ascorbate and sorafenib in hepatocellular carcinoma: New insights into ascorbate cytotoxicity.

Rouleau L, Antony AN, Bisetto S, Newberg A, Doria C, Levine M, Monti DA, Hoek JB.

Free Radic Biol Med. 2016 Jun;95:308-322. doi: 10.1016/j.freeradbiomed.2016.03.031. Epub 2016 Mar 30.


Ascorbic acid repletion: A possible therapy for diabetic macular edema?

May JM.

Free Radic Biol Med. 2016 May;94:47-54. doi: 10.1016/j.freeradbiomed.2016.02.019. Epub 2016 Feb 17. Review.


Modulation of Cytokines in Cancer Patients by Intravenous Ascorbate Therapy.

Mikirova N, Riordan N, Casciari J.

Med Sci Monit. 2016 Jan 3;22:14-25.


Physiologic Doses of Ascorbic Acid Increase Arsenic Trioxide Toxicity in Human Jurkat -T Lymphoma Cells.

Yedjou CG, Byrd R, Allen L, Tchounwou PB.

Met Ions Biol Med. 2011;11:236-241.


Molecular expression and functional activity of vitamin C specific transport system (SVCT2) in human breast cancer cells.

Khurana V, Kwatra D, Pal D, Mitra AK.

Int J Pharm. 2014 Oct 20;474(1-2):14-24. doi: 10.1016/j.ijpharm.2014.07.056. Epub 2014 Aug 4.


Vitamin C modulates DNA damage induced by hydrogen peroxide in human colorectal adenocarcinoma cell lines (HT29) estimated by comet assay in vitro.

Kontek R, Kontek B, Grzegorczyk K.

Arch Med Sci. 2013 Dec 30;9(6):1006-12. doi: 10.5114/aoms.2013.39791. Epub 2013 Dec 26.


The ROS-induced cytotoxicity of ascorbate is attenuated by hypoxia and HIF-1alpha in the NCI60 cancer cell lines.

Sinnberg T, Noor S, Venturelli S, Berger A, Schuler P, Garbe C, Busch C.

J Cell Mol Med. 2014 Mar;18(3):530-41. doi: 10.1111/jcmm.12207. Epub 2013 Dec 14.


SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways.

Batinic-Haberle I, Tovmasyan A, Roberts ER, Vujaskovic Z, Leong KW, Spasojevic I.

Antioxid Redox Signal. 2014 May 20;20(15):2372-415. doi: 10.1089/ars.2012.5147. Epub 2013 Oct 1. Review.


Phase I clinical trial to evaluate the safety, tolerability, and pharmacokinetics of high-dose intravenous ascorbic acid in patients with advanced cancer.

Stephenson CM, Levin RD, Spector T, Lis CG.

Cancer Chemother Pharmacol. 2013 Jul;72(1):139-46. doi: 10.1007/s00280-013-2179-9. Epub 2013 May 14.


Preclinical demonstration of synergistic Active Nutrients/Drug (AND) combination as a potential treatment for malignant pleural mesothelioma.

Volta V, Ranzato E, Martinotti S, Gallo S, Russo MV, Mutti L, Biffo S, Burlando B.

PLoS One. 2013;8(3):e58051. doi: 10.1371/journal.pone.0058051. Epub 2013 Mar 6.


Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators.

Tovmasyan A, Sheng H, Weitner T, Arulpragasam A, Lu M, Warner DS, Vujaskovic Z, Spasojevic I, Batinic-Haberle I.

Med Princ Pract. 2013;22(2):103-30. doi: 10.1159/000341715. Epub 2012 Oct 16. Review.


Effect of ascorbic acid and hydrogen peroxide on mouse neuroblastoma cells.

Hardaway CM, Badisa RB, Soliman KF.

Mol Med Rep. 2012 Jun;5(6):1449-52. doi: 10.3892/mmr.2012.857. Epub 2012 Apr 2.


Vitamin C: a concentration-function approach yields pharmacology and therapeutic discoveries.

Levine M, Padayatty SJ, Espey MG.

Adv Nutr. 2011 Mar;2(2):78-88. doi: 10.3945/an.110.000109. Epub 2011 Mar 10. Review.


Phase I evaluation of intravenous ascorbic acid in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer.

Monti DA, Mitchell E, Bazzan AJ, Littman S, Zabrecky G, Yeo CJ, Pillai MV, Newberg AB, Deshmukh S, Levine M.

PLoS One. 2012;7(1):e29794. doi: 10.1371/journal.pone.0029794. Epub 2012 Jan 17.


Comment on "Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer," i.e., all we are saying is, give C a chance.

Cullen JJ, Spitz DR, Buettner GR.

Free Radic Biol Med. 2011 Jun 15;50(12):1726-7. doi: 10.1016/j.freeradbiomed.2011.03.030. Epub 2011 Apr 1. No abstract available.


Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer.

Espey MG, Chen P, Chalmers B, Drisko J, Sun AY, Levine M, Chen Q.

Free Radic Biol Med. 2011 Jun 1;50(11):1610-9. doi: 10.1016/j.freeradbiomed.2011.03.007. Epub 2011 Mar 12.


Vitamin C: intravenous use by complementary and alternative medicine practitioners and adverse effects.

Padayatty SJ, Sun AY, Chen Q, Espey MG, Drisko J, Levine M.

PLoS One. 2010 Jul 7;5(7):e11414. doi: 10.1371/journal.pone.0011414.


The prospects of vitamin C in cancer therapy.

Lee WJ.

Immune Netw. 2009 Oct;9(5):147-52. doi: 10.4110/in.2009.9.5.147. Epub 2009 Oct 30.


Ascorbic Acid Potentiation of Arsenic Trioxide Anticancer Activity Against Acute Promyelocytic Leukemia.

Yedjou C, Thuisseu L, Tchounwou C, Gomes M, Howard C, Tchounwou P.

Arch Drug Inf. 2009 Dec;2(4):59-65.


Redox control of the cell cycle in health and disease.

Sarsour EH, Kumar MG, Chaudhuri L, Kalen AL, Goswami PC.

Antioxid Redox Signal. 2009 Dec;11(12):2985-3011. doi: 10.1089/ARS.2009.2513. Review.

Supplemental Content

Support Center