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Items: 1 to 20 of 35


The Indirubin Derivative 6-Bromoindirubin-3'-Oxime Activates Proteostatic Modules, Reprograms Cellular Bioenergetic Pathways, and Exerts Antiaging Effects.

Tsakiri EN, Gaboriaud-Kolar N, Iliaki KK, Tchoumtchoua J, Papanagnou ED, Chatzigeorgiou S, Tallas KD, Mikros E, Halabalaki M, Skaltsounis AL, Trougakos IP.

Antioxid Redox Signal. 2017 Nov 10;27(14):1027-1047. doi: 10.1089/ars.2016.6910. Epub 2017 May 16.


Modulation of glycogen synthase kinase-3β following TRAIL combinatorial treatment in cancer cells.

Santha S, Davaakhuu G, Basu A, Ke R, Das S, Rana A, Rana B.

Oncotarget. 2016 Oct 11;7(41):66892-66905. doi: 10.18632/oncotarget.11834.


Toll-like receptor 4-mediated signaling participates in apoptosis of hippocampal neurons.

He Y, Zhou A, Jiang W.

Neural Regen Res. 2013 Oct 15;8(29):2744-53. doi: 10.3969/j.issn.1673-5374.2013.29.006.


Activation of muscarinic receptors inhibits glutamate-induced GSK-3β overactivation in PC12 cells.

Ma K, Yang LM, Chen HZ, Lu Y.

Acta Pharmacol Sin. 2013 Jul;34(7):886-92. doi: 10.1038/aps.2013.42. Epub 2013 May 20.


Nerve growth factor stimulates cardiac regeneration via cardiomyocyte proliferation in experimental heart failure.

Lam NT, Currie PD, Lieschke GJ, Rosenthal NA, Kaye DM.

PLoS One. 2012;7(12):e53210. doi: 10.1371/journal.pone.0053210. Epub 2012 Dec 31.


Specific roles of Akt iso forms in apoptosis and axon growth regulation in neurons.

Diez H, Garrido JJ, Wandosell F.

PLoS One. 2012;7(4):e32715. doi: 10.1371/journal.pone.0032715. Epub 2012 Apr 11.


Insulin in central nervous system: more than just a peripheral hormone.

Duarte AI, Moreira PI, Oliveira CR.

J Aging Res. 2012;2012:384017. doi: 10.1155/2012/384017. Epub 2012 Feb 21.


GSK-3 Inhibitors: Preclinical and Clinical Focus on CNS.

Eldar-Finkelman H, Martinez A.

Front Mol Neurosci. 2011 Oct 31;4:32. doi: 10.3389/fnmol.2011.00032. eCollection 2011.


Deconstructing GSK-3: The Fine Regulation of Its Activity.

Medina M, Wandosell F.

Int J Alzheimers Dis. 2011;2011:479249. doi: 10.4061/2011/479249. Epub 2011 Apr 28.


Neuronal pentraxin 1 induction in hypoxic-ischemic neuronal death is regulated via a glycogen synthase kinase-3α/β dependent mechanism.

Russell JC, Kishimoto K, O'Driscoll C, Hossain MA.

Cell Signal. 2011 Apr;23(4):673-82. doi: 10.1016/j.cellsig.2010.11.021. Epub 2010 Dec 3.


Inhibitory phosphorylation of GSK-3 by CaMKII couples depolarization to neuronal survival.

Song B, Lai B, Zheng Z, Zhang Y, Luo J, Wang C, Chen Y, Woodgett JR, Li M.

J Biol Chem. 2010 Dec 24;285(52):41122-34. doi: 10.1074/jbc.M110.130351. Epub 2010 Sep 14.


Wnt signal transduction pathway and apoptosis: a review.

Pećina-Slaus N.

Cancer Cell Int. 2010 Jun 30;10:22. doi: 10.1186/1475-2867-10-22.


Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease.

Gómez Ravetti M, Rosso OA, Berretta R, Moscato P.

PLoS One. 2010 Apr 13;5(4):e10153. doi: 10.1371/journal.pone.0010153.


E3 ligase Nedd4 promotes axon branching by downregulating PTEN.

Drinjakovic J, Jung H, Campbell DS, Strochlic L, Dwivedy A, Holt CE.

Neuron. 2010 Feb 11;65(3):341-57. doi: 10.1016/j.neuron.2010.01.017.


P2X7, NMDA and BDNF receptors converge on GSK3 phosphorylation and cooperate to promote survival in cerebellar granule neurons.

Ortega F, Pérez-Sen R, Morente V, Delicado EG, Miras-Portugal MT.

Cell Mol Life Sci. 2010 May;67(10):1723-33. doi: 10.1007/s00018-010-0278-x. Epub 2010 Feb 10.


Acute estradiol protects CA1 neurons from ischemia-induced apoptotic cell death via the PI3K/Akt pathway.

Jover-Mengual T, Miyawaki T, Latuszek A, Alborch E, Zukin RS, Etgen AM.

Brain Res. 2010 Mar 19;1321:1-12. doi: 10.1016/j.brainres.2010.01.046. Epub 2010 Jan 28.


GSK3beta in ethanol neurotoxicity.

Luo J.

Mol Neurobiol. 2009 Oct;40(2):108-21. doi: 10.1007/s12035-009-8075-y. Epub 2009 Jun 9. Review.


Overexpression of glycogen synthase kinase 3beta sensitizes neuronal cells to ethanol toxicity.

Liu Y, Chen G, Ma C, Bower KA, Xu M, Fan Z, Shi X, Ke ZJ, Luo J.

J Neurosci Res. 2009 Sep;87(12):2793-802. doi: 10.1002/jnr.22098.


Overexpression screen in Drosophila identifies neuronal roles of GSK-3 beta/shaggy as a regulator of AP-1-dependent developmental plasticity.

Franciscovich AL, Mortimer AD, Freeman AA, Gu J, Sanyal S.

Genetics. 2008 Dec;180(4):2057-71. doi: 10.1534/genetics.107.085555. Epub 2008 Oct 1.

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