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Items: 1 to 20 of 127


The involvement and possible mechanism of NR4A1 in chondrocyte apoptosis during osteoarthritis.

Shi X, Ye H, Yao X, Gao Y.

Am J Transl Res. 2017 Feb 15;9(2):746-754. eCollection 2017.


PAX3-FOXO1A Expression in Rhabdomyosarcoma Is Driven by the Targetable Nuclear Receptor NR4A1.

Lacey A, Rodrigues-Hoffman A, Safe S.

Cancer Res. 2017 Feb 1;77(3):732-741. doi: 10.1158/0008-5472.CAN-16-1546. Epub 2016 Nov 18.


Adenovirus-mediated expression of orphan nuclear receptor NR4A2 targeting hepatic stellate cell attenuates liver fibrosis in rats.

Chen P, Li J, Huo Y, Lu J, Wan L, Yang Q, Huang J, Gan R, Guo C.

Sci Rep. 2016 Sep 20;6:33593. doi: 10.1038/srep33593.


Roles of d-Amino Acids on the Bioactivity of Host Defense Peptides.

Li H, Anuwongcharoen N, Malik AA, Prachayasittikul V, Wikberg JE, Nantasenamat C.

Int J Mol Sci. 2016 Jun 30;17(7). pii: E1023. doi: 10.3390/ijms17071023. Review.


Orphan Nuclear Receptor NR4A1 Binds a Novel Protein Interaction Site on Anti-apoptotic B Cell Lymphoma Gene 2 Family Proteins.

Godoi PH, Wilkie-Grantham RP, Hishiki A, Sano R, Matsuzawa Y, Yanagi H, Munte CE, Chen Y, Yao Y, Marassi FM, Kalbitzer HR, Matsuzawa S, Reed JC.

J Biol Chem. 2016 Jul 1;291(27):14072-84. doi: 10.1074/jbc.M116.715235. Epub 2016 Apr 19.


Pronounced peptide selectivity for melanoma through tryptophan end-tagging.

Duong DT, Singh S, Bagheri M, Verma NK, Schmidtchen A, Malmsten M.

Sci Rep. 2016 Apr 27;6:24952. doi: 10.1038/srep24952.


High expression of orphan nuclear receptor NR4A1 in a subset of ovarian tumors with worse outcome.

Delgado E, Boisen MM, Laskey R, Chen R, Song C, Sallit J, Yochum ZA, Andersen CL, Sikora MJ, Wagner J, Safe S, Elishaev E, Lee A, Edwards RP, Haluska P, Tseng G, Schurdak M, Oesterreich S.

Gynecol Oncol. 2016 May;141(2):348-56. doi: 10.1016/j.ygyno.2016.02.030. Epub 2016 Mar 11.


TR3 is preferentially expressed by bulge epithelial stem cells in human hair follicles.

Xie L, Yang R, Liu S, Lyle S, Cotsarelis G, Xiang L, Zhang L, Li B, Wan M, Xu X.

Lab Invest. 2016 Jan;96(1):81-8. doi: 10.1038/labinvest.2015.125. Epub 2015 Nov 2.


Honokiol sensitizes breast cancer cells to TNF-α induction of apoptosis by inhibiting Nur77 expression.

Xie L, Jiang F, Zhang X, Alitongbieke G, Shi X, Meng M, Xu Y, Ren A, Wang J, Cai L, Zhou Y, Xu Y, Su Y, Liu J, Zeng Z, Wang G, Zhou H, Chen QC, Zhang XK.

Br J Pharmacol. 2016 Jan;173(2):344-56. doi: 10.1111/bph.13375. Epub 2015 Dec 16.


Targeting truncated RXRα for cancer therapy.

Zhang X, Zhou H, Su Y.

Acta Biochim Biophys Sin (Shanghai). 2016 Jan;48(1):49-59. doi: 10.1093/abbs/gmv104. Epub 2015 Oct 21. Review.


The Orphan Nuclear Receptor NR4A1 Protects Pancreatic β-Cells from Endoplasmic Reticulum (ER) Stress-mediated Apoptosis.

Yu C, Cui S, Zong C, Gao W, Xu T, Gao P, Chen J, Qin D, Guan Q, Liu Y, Fu Y, Li X, Wang X.

J Biol Chem. 2015 Aug 21;290(34):20687-99. doi: 10.1074/jbc.M115.654863. Epub 2015 Jul 8.


NSC-640358 acts as RXRα ligand to promote TNFα-mediated apoptosis of cancer cell.

Chen F, Chen J, Lin J, Cheltsov AV, Xu L, Chen Y, Zeng Z, Chen L, Huang M, Hu M, Ye X, Zhou Y, Wang G, Su Y, Zhang L, Zhou F, Zhang XK, Zhou H.

Protein Cell. 2015 Sep;6(9):654-666. doi: 10.1007/s13238-015-0178-9. Epub 2015 Jul 9.


Requirement of novel amino acid fragments of orphan nuclear receptor TR3/Nur77 for its functions in angiogenesis.

Li Y, Bourbon PM, Grant MA, Peng J, Ye T, Zhao D, Zeng H.

Oncotarget. 2015 Sep 15;6(27):24261-76.


Nuclear Receptor 4A1 (NR4A1) as a Drug Target for Renal Cell Adenocarcinoma.

Hedrick E, Lee SO, Kim G, Abdelrahim M, Jin UH, Safe S, Abudayyeh A.

PLoS One. 2015 Jun 2;10(6):e0128308. doi: 10.1371/journal.pone.0128308. eCollection 2015.


Nuclear receptor 4A (NR4A) family - orphans no more.

Safe S, Jin UH, Morpurgo B, Abudayyeh A, Singh M, Tjalkens RB.

J Steroid Biochem Mol Biol. 2016 Mar;157:48-60. doi: 10.1016/j.jsbmb.2015.04.016. Epub 2015 Apr 23.


Apoptosis Signal-regulating Kinase 1 (ASK1)-p38 Pathway-dependent Cytoplasmic Translocation of the Orphan Nuclear Receptor NR4A2 Is Required for Oxidative Stress-induced Necrosis.

Watanabe T, Sekine S, Naguro I, Sekine Y, Ichijo H.

J Biol Chem. 2015 Apr 24;290(17):10791-803. doi: 10.1074/jbc.M114.623280. Epub 2015 Mar 9.


The interplay of NR4A receptors and the oncogene-tumor suppressor networks in cancer.

Beard JA, Tenga A, Chen T.

Cell Signal. 2015 Feb;27(2):257-66. doi: 10.1016/j.cellsig.2014.11.009. Epub 2014 Nov 15. Review.


Regulation of the nongenomic actions of retinoid X receptor-α by targeting the coregulator-binding sites.

Zhang XK, Su Y, Chen L, Chen F, Liu J, Zhou H.

Acta Pharmacol Sin. 2015 Jan;36(1):102-12. doi: 10.1038/aps.2014.109. Epub 2014 Dec 1. Review.


The orphan nuclear receptor NR4A1 specifies a distinct subpopulation of quiescent myeloid-biased long-term HSCs.

Land RH, Rayne AK, Vanderbeck AN, Barlowe TS, Manjunath S, Gross M, Eiger S, Klein PS, Cunningham NR, Huang J, Emerson SG, Punt JA.

Stem Cells. 2015 Jan;33(1):278-88. doi: 10.1002/stem.1852.


Induction of Nur77-dependent apoptotic pathway by a coumarin derivative through activation of JNK and p38 MAPK.

Zhou Y, Zhao W, Xie G, Huang M, Hu M, Jiang X, Zeng D, Liu J, Zhou H, Chen H, Wang GH, Zhang XK.

Carcinogenesis. 2014 Dec;35(12):2660-9. doi: 10.1093/carcin/bgu186. Epub 2014 Sep 3.

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