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Nanomedicine engulfed by macrophages for targeted tumor therapy.

Li S, Feng S, Ding L, Liu Y, Zhu Q, Qian Z, Gu Y.

Int J Nanomedicine. 2016 Aug 23;11:4107-24. doi: 10.2147/IJN.S110146.


Protonation and Trapping of a Small pH-Sensitive Near-Infrared Fluorescent Molecule in the Acidic Tumor Environment Delineate Diverse Tumors in Vivo.

Gilson RC, Tang R, Som A, Klajer C, Sarder P, Sudlow GP, Akers WJ, Achilefu S.

Mol Pharm. 2015 Dec 7;12(12):4237-46. doi: 10.1021/acs.molpharmaceut.5b00430.


Visualization of pulmonary clearance mechanisms via noninvasive optical imaging validated by near-infrared flow cytometry.

Zhou H, Gunsten SP, Zhegalova NG, Bloch S, Achilefu S, Christopher Holley J, Schweppe D, Akers W, Brody SL, Eades WC, Berezin MY.

Cytometry A. 2015 May;87(5):419-27. doi: 10.1002/cyto.a.22658.


In vivo molecular mapping of the tumor microenvironment in an azoxymethane-treated mouse model of colon carcinogenesis.

Leung SJ, Rice PS, Barton JK.

Lasers Surg Med. 2015 Jan;47(1):40-9. doi: 10.1002/lsm.22309.


Multispectral measurement of contrast in tissue-mimicking phantoms in near-infrared spectral range of 650 to 1600 nm.

Salo D, Zhang H, Kim DM, Berezin MY.

J Biomed Opt. 2014 Aug;19(8):086008. doi: 10.1117/1.JBO.19.8.086008.


Photons across medicine: relating optical and nuclear imaging.

Nordstrom R, Cherry S, Azhdarinia A, Sevick-Muraca E, Vanbrocklin H.

Biomed Opt Express. 2013 Nov 5;4(12):2751-62. doi: 10.1364/BOE.4.002751.


Photoacoustic Imaging for Cancer Detection and Staging.

Mehrmohammadi M, Yoon SJ, Yeager D, Emelianov SY.

Curr Mol Imaging. 2013 Mar;2(1):89-105.


Evaluation of polymethine dyes as potential probes for near infrared fluorescence imaging of tumors: part - 1.

James NS, Chen Y, Joshi P, Ohulchanskyy TY, Ethirajan M, Henary M, Strekowsk L, Pandey RK.

Theranostics. 2013 Aug 21;3(9):692-702. doi: 10.7150/thno.5922.


Multispectral imaging in the extended near-infrared window based on endogenous chromophores.

Cao Q, Zhegalova NG, Wang ST, Akers WJ, Berezin MY.

J Biomed Opt. 2013 Oct;18(10):101318. doi: 10.1117/1.JBO.18.10.101318.


Near-infrared fluorescence goggle system with complementary metal-oxide-semiconductor imaging sensor and see-through display.

Liu Y, Njuguna R, Matthews T, Akers WJ, Sudlow GP, Mondal S, Tang R, Gruev V, Achilefu S.

J Biomed Opt. 2013 Oct;18(10):101303. doi: 10.1117/1.JBO.18.10.101303.


Click Reaction-Mediated Functionalization of Near-Infrared Pyrrolopyrrole Cyanine Dyes for Biological Imaging Applications.

Zhou M, Zhang X, Bai M, Shen D, Xu B, Kao J, Xia G, Achilefu S.

RSC Adv. 2013 May 21;3(19):6756-6758.



Gustafson TP, Dergunov SA, Akers WJ, Cao Q, Magalotti S, Achilefu S, Pinkhassik E, Berezin MY.

RSC Adv. 2013 Jan 24;3(16):5547-5555.


Dual fluorescent molecular substrates selectively report the activation, sustainability and reversibility of cellular PKB/Akt activity.

Shen D, Bai M, Tang R, Xu B, Ju X, Pestell RG, Achilefu S.

Sci Rep. 2013;3:1697. doi: 10.1038/srep01697.


Intraoperative detection of liver tumors aided by a fluorescence goggle system and multimodal imaging.

Liu Y, Akers WJ, Bauer AQ, Mondal S, Gullicksrud K, Sudlow GP, Culver JP, Achilefu S.

Analyst. 2013 Apr 21;138(8):2254-7. doi: 10.1039/c3an00165b.


Combined hemoglobin and fluorescence diffuse optical tomography for breast tumor diagnosis: a pilot study on time-domain methodology.

Zhang W, Wu L, Li J, Yi X, Wang X, Lu Y, Chen W, Zhou Z, Zhang L, Zhao H, Gao F.

Biomed Opt Express. 2013 Feb 1;4(2):331-48. doi: 10.1364/BOE.4.000331.


Optical imaging in breast cancer diagnosis: the next evolution.

Herranz M, Ruibal A.

J Oncol. 2012;2012:863747. doi: 10.1155/2012/863747.


Molecular imaging probe development: a chemistry perspective.

Nolting DD, Nickels ML, Guo N, Pham W.

Am J Nucl Med Mol Imaging. 2012 Jul 10;2(3):273-306.


Near-infrared fluorescent divalent RGD ligand for integrin αvβ₃-targeted optical imaging.

Ye Y, Akers W, Xu B, Bloch S, Odonkor C, Achilefu S.

Bioorg Med Chem Lett. 2012 Sep 1;22(17):5405-9. doi: 10.1016/j.bmcl.2012.07.044.


Highly sensitive detection of cancer cells using femtosecond dual-wavelength near-IR two-photon imaging.

Starkey JR, Makarov NS, Drobizhev M, Rebane A.

Biomed Opt Express. 2012 Jul 1;3(7):1534-47. doi: 10.1364/BOE.3.001534.

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