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Tumour biomarkers: homeostasis as a novel prognostic indicator.

Falco M, Palma G, Rea D, De Biase D, Scala S, D'Aiuto M, Facchini G, Perdonà S, Barbieri A, Arra C.

Open Biol. 2016 Dec;6(12). pii: 160254. Review.


Epigenetic therapy approaches in non-small cell lung cancer: Update and perspectives.

Schiffmann I, Greve G, Jung M, Lübbert M.

Epigenetics. 2016 Dec;11(12):858-870. Epub 2016 Nov 15.


Epigenetics in non-small cell lung cancer: from basics to therapeutics.

Ansari J, Shackelford RE, El-Osta H.

Transl Lung Cancer Res. 2016 Apr;5(2):155-71. doi: 10.21037/tlcr.2016.02.02. Review.


Clinicopathological significance and a potential drugtarget of RARβ in non-small-cell lung carcinoma: a meta-analysis and a systematic review.

Song X, Shi K, Zhou SJ, Yu DP, Liu Z, Han Y.

Drug Des Devel Ther. 2016 Apr 6;10:1345-54. doi: 10.2147/DDDT.S96766. eCollection 2016. Review.


Non-DHFR-mediated effects of methotrexate in osteosarcoma cell lines: epigenetic alterations and enhanced cell differentiation.

Sramek M, Neradil J, Sterba J, Veselska R.

Cancer Cell Int. 2016 Feb 29;16:14. doi: 10.1186/s12935-016-0289-2. eCollection 2016.


Vitamin A depletion induced by cigarette smoke is associated with an increase in lung cancer-related markers in rats.

Xue Y, Harris E, Wang W, Baybutt RC.

J Biomed Sci. 2015 Oct 14;22:84. doi: 10.1186/s12929-015-0189-0.


Regulation of Retinoic Acid Receptor Beta by Interleukin-15 in the Lung during Cigarette Smoking and Influenza Virus Infection.

Wang J, Liu W, Marion C, Singh R, Andrews N, Lee CG, Elias JA, Dela Cruz CS.

Am J Respir Cell Mol Biol. 2015 Dec;53(6):822-33. doi: 10.1165/rcmb.2014-0448OC.


RARβ2 hypermethylation is associated with poor recurrence-free survival in never-smokers with adenocarcinoma of the lung.

Kim Y, Jin D, Lee BB, Cho EY, Han J, Shim YM, Kim DH.

Clin Epigenetics. 2015 Mar 19;7:32. doi: 10.1186/s13148-015-0066-4. eCollection 2015.


Epigenetics of lung cancer.

Langevin SM, Kratzke RA, Kelsey KT.

Transl Res. 2015 Jan;165(1):74-90. doi: 10.1016/j.trsl.2014.03.001. Epub 2014 Mar 12. Review.


Maintaining the unmethylated state.

Smith SS.

Clin Epigenetics. 2013 Sep 30;5(1):17. doi: 10.1186/1868-7083-5-17.


The association of retinoic acid receptor beta2(RARβ2) methylation status and prostate cancer risk: a systematic review and meta-analysis.

Gao T, He B, Pan Y, Li R, Xu Y, Chen L, Nie Z, Gu L, Wang S.

PLoS One. 2013 May 13;8(5):e62950. doi: 10.1371/journal.pone.0062950. Print 2013. Review.


Significant frequency of allelic imbalance in 3p region covering RARβ and MLH1 loci seems to be essential in molecular non-small cell lung cancer diagnosis.

Antczak A, Migdalska-Sęk M, Pastuszak-Lewandoska D, Czarnecka K, Nawrot E, Domańska D, Kordiak J, Górski P, Brzeziańska E.

Med Oncol. 2013 Jun;30(2):532. doi: 10.1007/s12032-013-0532-9. Epub 2013 Mar 17.


Specific Biomarkers Are Associated with Docetaxeland Gemcitabine-Resistant NSCLC Cell Lines.

Pasini A, Paganelli G, Tesei A, Zoli W, Giordano E, Calistri D.

Transl Oncol. 2012 Dec;5(6):461-8. Epub 2012 Dec 1.


Methylation of the RASSF1A and RARβ genes as a candidate biomarker for lung cancer.

Li W, Deng J, Jiang P, Zeng X, Hu S, Tang J.

Exp Ther Med. 2012 Jun;3(6):1067-1071. Epub 2012 Mar 15.


DNA methylation biomarkers offer improved diagnostic efficiency in lung cancer.

Nikolaidis G, Raji OY, Markopoulou S, Gosney JR, Bryan J, Warburton C, Walshaw M, Sheard J, Field JK, Liloglou T.

Cancer Res. 2012 Nov 15;72(22):5692-701. doi: 10.1158/0008-5472.CAN-12-2309. Epub 2012 Sep 7.


Research resource: Diagnostic and therapeutic potential of nuclear receptor expression in lung cancer.

Jeong Y, Xie Y, Lee W, Bookout AL, Girard L, Raso G, Behrens C, Wistuba II, Gadzar AF, Minna JD, Mangelsdorf DJ.

Mol Endocrinol. 2012 Aug;26(8):1443-54. doi: 10.1210/me.2011-1382. Epub 2012 Jun 14.


Molecular determinants of retinoic acid sensitivity in pancreatic cancer.

Gupta S, Pramanik D, Mukherjee R, Campbell NR, Elumalai S, de Wilde RF, Hong SM, Goggins MG, De Jesus-Acosta A, Laheru D, Maitra A.

Clin Cancer Res. 2012 Jan 1;18(1):280-9. doi: 10.1158/1078-0432.CCR-11-2165. Epub 2011 Oct 18.


Combined α-tocopherol and ascorbic acid protects against smoke-induced lung squamous metaplasia in ferrets.

Kim Y, Chongviriyaphan N, Liu C, Russell RM, Wang XD.

Lung Cancer. 2012 Jan;75(1):15-23. doi: 10.1016/j.lungcan.2011.05.017. Epub 2011 Jun 12.


Effects of beta-carotene supplementation on molecular markers of lung carcinogenesis in male smokers.

Wright ME, Groshong SD, Husgafvel-Pursiainen K, Genova E, Lucia MS, Wolff H, Virtamo J, Albanes D.

Cancer Prev Res (Phila). 2010 Jun;3(6):745-52. doi: 10.1158/1940-6207.CAPR-09-0107. Epub 2010 May 18.


Expression profiling of nuclear receptors in the NCI60 cancer cell panel reveals receptor-drug and receptor-gene interactions.

Holbeck S, Chang J, Best AM, Bookout AL, Mangelsdorf DJ, Martinez ED.

Mol Endocrinol. 2010 Jun;24(6):1287-96. doi: 10.1210/me.2010-0040. Epub 2010 Apr 7.

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