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Items: 1 to 20 of 124


High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble.

Ganser LR, Lee J, Rangadurai A, Merriman DK, Kelly ML, Kansal AD, Sathyamoorthy B, Al-Hashimi HM.

Nat Struct Mol Biol. 2018 May;25(5):425-434. doi: 10.1038/s41594-018-0062-4. Epub 2018 May 4.


New tRNA contacts facilitate ligand binding in a Mycobacterium smegmatis T box riboswitch.

Sherwood AV, Frandsen JK, Grundy FJ, Henkin TM.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3894-3899. doi: 10.1073/pnas.1721254115. Epub 2018 Mar 26.


Kinetic analysis of the isoleucyl-tRNA synthetase mechanism: the next reaction cycle can start before the previous one ends.

Airas RK.

FEBS Open Bio. 2017 Dec 20;8(2):244-255. doi: 10.1002/2211-5463.12362. eCollection 2018 Feb.


Life under the Microscope: Single-Molecule Fluorescence Highlights the RNA World.

Ray S, Widom JR, Walter NG.

Chem Rev. 2018 Apr 25;118(8):4120-4155. doi: 10.1021/acs.chemrev.7b00519. Epub 2018 Jan 24.


Swellix: a computational tool to explore RNA conformational space.

Sloat N, Liu JW, Schroeder SJ.

BMC Bioinformatics. 2017 Nov 21;18(1):504. doi: 10.1186/s12859-017-1910-7.


Cold adaptation of tRNA nucleotidyltransferases: A tradeoff in activity, stability and fidelity.

Ernst FGM, Erber L, Sammler J, Jühling F, Betat H, Mörl M.

RNA Biol. 2018 Jan 2;15(1):144-155. doi: 10.1080/15476286.2017.1391445. Epub 2017 Nov 21.


Molecular recognition of pre-tRNA by Arabidopsis protein-only Ribonuclease P.

Klemm BP, Karasik A, Kaitany KJ, Shanmuganathan A, Henley MJ, Thelen AZ, Dewar AJL, Jackson ND, Koutmos M, Fierke CA.

RNA. 2017 Dec;23(12):1860-1873. doi: 10.1261/rna.061457.117. Epub 2017 Sep 5.


DSSR-enhanced visualization of nucleic acid structures in Jmol.

Hanson RM, Lu XJ.

Nucleic Acids Res. 2017 Jul 3;45(W1):W528-W533. doi: 10.1093/nar/gkx365.


Idiosyncratic recognition of UUG/UUA codons by modified nucleoside 5-taurinomethyluridine, τm5U present at 'wobble' position in anticodon loop of tRNALeu: A molecular modeling approach.

Kamble AS, Fandilolu PM, Sambhare SB, Sonawane KD.

PLoS One. 2017 Apr 28;12(4):e0176756. doi: 10.1371/journal.pone.0176756. eCollection 2017.


tRNA Modifications: Impact on Structure and Thermal Adaptation.

Lorenz C, Lünse CE, Mörl M.

Biomolecules. 2017 Apr 4;7(2). pii: E35. doi: 10.3390/biom7020035. Review.


Chemical and Conformational Diversity of Modified Nucleosides Affects tRNA Structure and Function.

Väre VY, Eruysal ER, Narendran A, Sarachan KL, Agris PF.

Biomolecules. 2017 Mar 16;7(1). pii: E29. doi: 10.3390/biom7010029. Review.


The structure of an E. coli tRNAfMet A1-U72 variant shows an unusual conformation of the A1-U72 base pair.

Monestier A, Aleksandrov A, Coureux PD, Panvert M, Mechulam Y, Schmitt E.

RNA. 2017 May;23(5):673-682. doi: 10.1261/rna.057877.116. Epub 2017 Jan 31.


Divalent ion competition reveals reorganization of an RNA ion atmosphere upon folding.

Trachman RJ 3rd, Draper DE.

Nucleic Acids Res. 2017 May 5;45(8):4733-4742. doi: 10.1093/nar/gkw1327.


Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution.

Hilal T, Yamamoto H, Loerke J, Bürger J, Mielke T, Spahn CM.

Nat Commun. 2016 Dec 20;7:13521. doi: 10.1038/ncomms13521.


Activation mode of the eukaryotic m2G10 tRNA methyltransferase Trm11 by its partner protein Trm112.

Bourgeois G, Marcoux J, Saliou JM, Cianférani S, Graille M.

Nucleic Acids Res. 2017 Feb 28;45(4):1971-1982. doi: 10.1093/nar/gkw1271.


Nucleobases Undergo Dynamic Rearrangements during RNA Tertiary Folding.

Welty R, Hall KB.

J Mol Biol. 2016 Nov 6;428(22):4490-4502. doi: 10.1016/j.jmb.2016.09.015. Epub 2016 Sep 29.


In vivo single-RNA tracking shows that most tRNA diffuses freely in live bacteria.

Plochowietz A, Farrell I, Smilansky Z, Cooperman BS, Kapanidis AN.

Nucleic Acids Res. 2017 Jan 25;45(2):926-937. doi: 10.1093/nar/gkw787. Epub 2016 Sep 12.


Structural effects of modified ribonucleotides and magnesium in transfer RNAs.

Xu Y, MacKerell AD Jr, Nilsson L.

Bioorg Med Chem. 2016 Oct 15;24(20):4826-4834. doi: 10.1016/j.bmc.2016.06.037. Epub 2016 Jun 18.


The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.

Schaffer MF, Peng G, Spingler B, Schnabl J, Wang M, Olieric V, Sigel RK.

Int J Mol Sci. 2016 Jun 27;17(7). pii: E988. doi: 10.3390/ijms17070988.


The Diversity of Ribonuclease P: Protein and RNA Catalysts with Analogous Biological Functions.

Klemm BP, Wu N, Chen Y, Liu X, Kaitany KJ, Howard MJ, Fierke CA.

Biomolecules. 2016 May 13;6(2). pii: E27. doi: 10.3390/biom6020027. Review.

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