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Items: 1 to 20 of 29

1.

Effects of Opium Addiction and Cigarette Smoking on Hematological Parameters.

Shahabinejad G, Sirati-Sabet M, Kazemi-Arababadi M, Nabati S, Asadikaram G.

Addict Health. 2016 Jul;8(3):179-185.

2.

Noscapine targets EGFRp-Tyr1068 to suppress the proliferation and invasion of MG63 cells.

He M, Jiang L, Ren Z, Wang G, Wang J.

Sci Rep. 2016 Nov 10;6:37062. doi: 10.1038/srep37062.

3.

A new antiproliferative noscapine analogue: chemical synthesis and biological evaluation.

Ghaly PE, Abou El-Magd RM, Churchill CD, Tuszynski JA, West FG.

Oncotarget. 2016 Jun 28;7(26):40518-40530. doi: 10.18632/oncotarget.9642.

4.

Engineering biosynthesis of the anticancer alkaloid noscapine in yeast.

Li Y, Smolke CD.

Nat Commun. 2016 Jul 5;7:12137. doi: 10.1038/ncomms12137.

5.

The Noscapine Chronicle: A Pharmaco-Historic Biography of the Opiate Alkaloid Family and its Clinical Applications.

Rida PC, LiVecche D, Ogden A, Zhou J, Aneja R.

Med Res Rev. 2015 Sep;35(5):1072-96. doi: 10.1002/med.21357. Epub 2015 Jul 14. Review.

6.

Noscapine recirculates enterohepatically and induces self-clearance.

Mukkavilli R, Gundala SR, Yang C, Jadhav GR, Vangala S, Reid MD, Aneja R.

Eur J Pharm Sci. 2015 Sep 18;77:90-9. doi: 10.1016/j.ejps.2015.05.026. Epub 2015 May 28.

7.

CYLD Regulates Noscapine Activity in Acute Lymphoblastic Leukemia via a Microtubule-Dependent Mechanism.

Yang Y, Ran J, Sun L, Sun X, Luo Y, Yan B, Tala, Liu M, Li D, Zhang L, Bao G, Zhou J.

Theranostics. 2015 Mar 2;5(7):656-66. doi: 10.7150/thno.10844. eCollection 2015.

8.

Design, synthesis and biological evaluation of di-substituted noscapine analogs as potent and microtubule-targeted anticancer agents.

Mishra RC, Gundala SR, Karna P, Lopus M, Gupta KK, Nagaraju M, Hamelberg D, Tandon V, Panda D, Reid MD, Aneja R.

Bioorg Med Chem Lett. 2015;25(10):2133-40. doi: 10.1016/j.bmcl.2015.03.076. Epub 2015 Mar 31.

9.

A novel effect of Noscapine on patients with massive ischemic stroke: A pseudo-randomized clinical trial.

Mahmoudian M, Rezvani M, Rohani M, Benaissa F, Jalili M, Ghourchian S.

Iran J Neurol. 2015 Jan 5;14(1):12-6.

10.

Novel third-generation water-soluble noscapine analogs as superior microtubule-interfering agents with enhanced antiproliferative activity.

Henary M, Narayana L, Ahad S, Gundala SR, Mukkavilli R, Sharma V, Owens EA, Yadav Y, Nagaraju M, Hamelberg D, Tandon V, Panda D, Aneja R.

Biochem Pharmacol. 2014 Nov 15;92(2):192-205. doi: 10.1016/j.bcp.2014.07.020. Epub 2014 Aug 11.

11.

Hematological changes in opium addicted diabetic rats.

Asadikaram G, Sirati-Sabet M, Asiabanha M, Shahrokhi N, Jafarzadeh A, Khaksari M.

Int J High Risk Behav Addict. 2013 Winter;1(4):141-8. doi: 10.5812/ijhrba.8777. Epub 2013 Mar 12.

12.

The protective activity of noscapine on renal ischemia-reperfusion injury in male Wistar rat.

Khanmoradi M, Ali Mard S, Aboutaleb N, Nobakht M, Mahmoudian M.

Iran J Basic Med Sci. 2014;17(4):244-9.

13.

In-Vitro and Ex-Vivo Investigations of the Microtubule Binding Drug Targetin on Angiogenesis.

Ajeawung NF, Mononen L, Thorn A, Pin AL, Joshi HC, Huot J, Kamnasaran D.

J Pediatr Oncol. 2013;1:41-47.

14.

Rational design, synthesis, and biological evaluation of third generation α-noscapine analogues as potent tubulin binding anti-cancer agents.

Manchukonda NK, Naik PK, Santoshi S, Lopus M, Joseph S, Sridhar B, Kantevari S.

PLoS One. 2013 Oct 21;8(10):e77970. doi: 10.1371/journal.pone.0077970. eCollection 2013.

15.

Synergistic suppression of noscapine and conventional chemotherapeutics on human glioblastoma cell growth.

Qi Q, Liu X, Li S, Joshi HC, Ye K.

Acta Pharmacol Sin. 2013 Jul;34(7):930-8. doi: 10.1038/aps.2013.40. Epub 2013 May 27.

16.

Noscapine induced apoptosis via downregulation of survivin in human neuroblastoma cells having wild type or null p53.

Li S, He J, Li S, Cao G, Tang S, Tong Q, Joshi HC.

PLoS One. 2012;7(7):e40076. doi: 10.1371/journal.pone.0040076. Epub 2012 Jul 26.

17.

Metabolic map and bioactivation of the anti-tumour drug noscapine.

Fang ZZ, Krausz KW, Li F, Cheng J, Tanaka N, Gonzalez FJ.

Br J Pharmacol. 2012 Nov;167(6):1271-86. doi: 10.1111/j.1476-5381.2012.02067.x.

18.

Second generation benzofuranone ring substituted noscapine analogs: synthesis and biological evaluation.

Mishra RC, Karna P, Gundala SR, Pannu V, Stanton RA, Gupta KK, Robinson MH, Lopus M, Wilson L, Henary M, Aneja R.

Biochem Pharmacol. 2011 Jul 15;82(2):110-21. doi: 10.1016/j.bcp.2011.03.029. Epub 2011 Apr 8.

19.

Drugs that target dynamic microtubules: a new molecular perspective.

Stanton RA, Gernert KM, Nettles JH, Aneja R.

Med Res Rev. 2011 May;31(3):443-81. doi: 10.1002/med.20242. Epub 2011 Mar 4. Review.

20.

A novel microtubule-modulating noscapinoid triggers apoptosis by inducing spindle multipolarity via centrosome amplification and declustering.

Karna P, Rida PC, Pannu V, Gupta KK, Dalton WB, Joshi H, Yang VW, Zhou J, Aneja R.

Cell Death Differ. 2011 Apr;18(4):632-44. doi: 10.1038/cdd.2010.133. Epub 2010 Nov 5.

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