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Items: 1 to 20 of 128

1.

An intronic mutation in Chd7 creates a cryptic splice site, causing aberrant splicing in a mouse model of CHARGE syndrome.

Ogier JM, Arhatari BD, Carpinelli MR, McColl BK, Wilson MA, Burt RA.

Sci Rep. 2018 Apr 3;8(1):5482. doi: 10.1038/s41598-018-23856-8.

2.

Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells.

Horn M, Kroef V, Allmeroth K, Schuller N, Miethe S, Peifer M, Penninger JM, Elling U, Denzel MS.

Oncotarget. 2018 Jan 23;9(11):9838-9851. doi: 10.18632/oncotarget.24305. eCollection 2018 Feb 9.

3.

Design and Evaluation of a Robotic Device for Automated Tail Vein Cannulations in Rodent Models.

Fromholtz A, Balter ML, Chen AI, Leipheimer JM, Shrirao A, Maguire TJ, Yarmush ML.

J Med Device. 2017 Dec;11(4):0410081-410087. doi: 10.1115/1.4038011. Epub 2017 Oct 16.

PMID:
29230256
4.
5.

Sensitized mutagenesis screen in Factor V Leiden mice identifies thrombosis suppressor loci.

Westrick RJ, Tomberg K, Siebert AE, Zhu G, Winn ME, Dobies SL, Manning SL, Brake MA, Cleuren AC, Hobbs LM, Mishack LM, Johnston AJ, Kotnik E, Siemieniak DR, Xu J, Li JZ, Saunders TL, Ginsburg D.

Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):9659-9664. doi: 10.1073/pnas.1705762114. Epub 2017 Aug 21.

6.

A mutation in Nischarin causes otitis media via LIMK1 and NF-κB pathways.

Crompton M, Purnell T, Tyrer HE, Parker A, Ball G, Hardisty-Hughes RE, Gale R, Williams D, Dean CH, Simon MM, Mallon AM, Wells S, Bhutta MF, Burton MJ, Tateossian H, Brown SDM.

PLoS Genet. 2017 Aug 14;13(8):e1006969. doi: 10.1371/journal.pgen.1006969. eCollection 2017 Aug.

7.

Next-generation mammalian genetics toward organism-level systems biology.

Susaki EA, Ukai H, Ueda HR.

NPJ Syst Biol Appl. 2017 Jun 5;3:15. doi: 10.1038/s41540-017-0015-2. eCollection 2017. Review.

8.

Pilot study of large-scale production of mutant pigs by ENU mutagenesis.

Hai T, Cao C, Shang H, Guo W, Mu Y, Yang S, Zhang Y, Zheng Q, Zhang T, Wang X, Liu Y, Kong Q, Li K, Wang D, Qi M, Hong Q, Zhang R, Wang X, Jia Q, Wang X, Qin G, Li Y, Luo A, Jin W, Yao J, Huang J, Zhang H, Li M, Xie X, Zheng X, Guo K, Wang Q, Zhang S, Li L, Xie F, Zhang Y, Weng X, Yin Z, Hu K, Cong Y, Zheng P, Zou H, Xin L, Xia J, Ruan J, Li H, Zhao W, Yuan J, Liu Z, Gu W, Li M, Wang Y, Wang H, Yang S, Liu Z, Wei H, Zhao J, Zhou Q, Meng A.

Elife. 2017 Jun 22;6. pii: e26248. doi: 10.7554/eLife.26248.

9.

Phylooncogenomics: Examining the cancer genome in the context of vertebrate evolution.

Zhang G, Vemulapalli TH, Yang JY.

Appl Transl Genom. 2013 Jun 29;2:48-54. eCollection 2013 Dec 1. Review.

10.

Loss-of-function genetic tools for animal models: cross-species and cross-platform differences.

Housden BE, Muhar M, Gemberling M, Gersbach CA, Stainier DY, Seydoux G, Mohr SE, Zuber J, Perrimon N.

Nat Rev Genet. 2017 Jan;18(1):24-40. doi: 10.1038/nrg.2016.118. Epub 2016 Oct 31. Review.

11.

G-protein-coupled receptor signaling and neural tube closure defects.

Shimada IS, Mukhopadhyay S.

Birth Defects Res. 2017 Jan 30;109(2):129-139. doi: 10.1002/bdra.23567.

12.

Decoding sORF translation - from small proteins to gene regulation.

Cabrera-Quio LE, Herberg S, Pauli A.

RNA Biol. 2016 Nov;13(11):1051-1059. Epub 2016 Aug 12. Review.

13.

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.

Potter PK, Bowl MR, Jeyarajan P, Wisby L, Blease A, Goldsworthy ME, Simon MM, Greenaway S, Michel V, Barnard A, Aguilar C, Agnew T, Banks G, Blake A, Chessum L, Dorning J, Falcone S, Goosey L, Harris S, Haynes A, Heise I, Hillier R, Hough T, Hoslin A, Hutchison M, King R, Kumar S, Lad HV, Law G, MacLaren RE, Morse S, Nicol T, Parker A, Pickford K, Sethi S, Starbuck B, Stelma F, Cheeseman M, Cross SH, Foster RG, Jackson IJ, Peirson SN, Thakker RV, Vincent T, Scudamore C, Wells S, El-Amraoui A, Petit C, Acevedo-Arozena A, Nolan PM, Cox R, Mallon AM, Brown SD.

Nat Commun. 2016 Aug 18;7:12444. doi: 10.1038/ncomms12444.

14.

Applicability, usability, and limitations of murine embryonic imaging with optical coherence tomography and optical projection tomography.

Singh M, Raghunathan R, Piazza V, Davis-Loiacono AM, Cable A, Vedakkan TJ, Janecek T, Frazier MV, Nair A, Wu C, Larina IV, Dickinson ME, Larin KV.

Biomed Opt Express. 2016 May 19;7(6):2295-310. doi: 10.1364/BOE.7.002295. eCollection 2016 Jun 1.

15.

Optical coherence tomography for embryonic imaging: a review.

Raghunathan R, Singh M, Dickinson ME, Larin KV.

J Biomed Opt. 2016 May 1;21(5):50902. doi: 10.1117/1.JBO.21.5.050902. No abstract available.

16.

Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking.

Militi S, Maywood ES, Sandate CR, Chesham JE, Barnard AR, Parsons MJ, Vibert JL, Joynson GM, Partch CL, Hastings MH, Nolan PM.

Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):2756-61. doi: 10.1073/pnas.1517549113. Epub 2016 Feb 22.

17.

Joint mouse-human phenome-wide association to test gene function and disease risk.

Wang X, Pandey AK, Mulligan MK, Williams EG, Mozhui K, Li Z, Jovaisaite V, Quarles LD, Xiao Z, Huang J, Capra JA, Chen Z, Taylor WL, Bastarache L, Niu X, Pollard KS, Ciobanu DC, Reznik AO, Tishkov AV, Zhulin IB, Peng J, Nelson SF, Denny JC, Auwerx J, Lu L, Williams RW.

Nat Commun. 2016 Feb 2;7:10464. doi: 10.1038/ncomms10464.

18.

The Snark was a Boojum - reloaded.

Macrì S, Richter SH.

Front Zool. 2015 Aug 24;12 Suppl 1:S20. doi: 10.1186/1742-9994-12-S1-S20. eCollection 2015. Review.

19.

The old and new face of craniofacial research: How animal models inform human craniofacial genetic and clinical data.

Van Otterloo E, Williams T, Artinger KB.

Dev Biol. 2016 Jul 15;415(2):171-187. doi: 10.1016/j.ydbio.2016.01.017. Epub 2016 Jan 22. Review.

20.

Towards a compendium of essential genes - From model organisms to synthetic lethality in cancer cells.

Zhan T, Boutros M.

Crit Rev Biochem Mol Biol. 2016;51(2):74-85. doi: 10.3109/10409238.2015.1117053. Epub 2015 Dec 1. Review.

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