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Items: 1 to 20 of 138


Chronic kidney disease induces autophagy leading to dysfunction of mitochondria in skeletal muscle.

Su Z, Klein JD, Du J, Franch HA, Zhang L, Hassounah F, Hudson MB, Wang XH.

Am J Physiol Renal Physiol. 2017 Jun 1;312(6):F1128-F1140. doi: 10.1152/ajprenal.00600.2016. Epub 2017 Apr 5.


Cytosolic BNIP3 Dimer Interacts with Mitochondrial BAX Forming Heterodimers in the Mitochondrial Outer Membrane under Basal Conditions.

Hendgen-Cotta UB, Esfeld S, Rudi K, Miinalainen I, Klare JP, Rassaf T.

Int J Mol Sci. 2017 Mar 23;18(4). pii: E687. doi: 10.3390/ijms18040687.


Resolution of TLR2-induced inflammation through manipulation of metabolic pathways in Rheumatoid Arthritis.

McGarry T, Biniecka M, Gao W, Cluxton D, Canavan M, Wade S, Wade S, Gallagher L, Orr C, Veale DJ, Fearon U.

Sci Rep. 2017 Feb 22;7:43165. doi: 10.1038/srep43165.


Discovery of Mieap-regulated mitochondrial quality control as a new function of tumor suppressor p53.

Nakamura Y, Arakawa H.

Cancer Sci. 2017 May;108(5):809-817. doi: 10.1111/cas.13208. Epub 2017 May 5. Review.


BNIP3 upregulation via stimulation of ERK and JNK activity is required for the protection of keratinocytes from UVB-induced apoptosis.

Moriyama M, Moriyama H, Uda J, Kubo H, Nakajima Y, Goto A, Morita T, Hayakawa T.

Cell Death Dis. 2017 Feb 2;8(2):e2576. doi: 10.1038/cddis.2017.4.


Caspase-Dependent and Caspase-Independent Pathways Are Involved in Cadmium-Induced Apoptosis in Primary Rat Proximal Tubular Cell Culture.

Liu G, Zou H, Luo T, Long M, Bian J, Liu X, Gu J, Yuan Y, Song R, Wang Y, Zhu J, Liu Z.

PLoS One. 2016 Nov 18;11(11):e0166823. doi: 10.1371/journal.pone.0166823. eCollection 2016.


BNIP3 Protein Suppresses PINK1 Kinase Proteolytic Cleavage to Promote Mitophagy.

Zhang T, Xue L, Li L, Tang C, Wan Z, Wang R, Tan J, Tan Y, Han H, Tian R, Billiar TR, Tao WA, Zhang Z.

J Biol Chem. 2016 Oct 7;291(41):21616-21629. Epub 2016 Aug 15.


Molecular Functions of Glycoconjugates in Autophagy.

Fahie K, Zachara NE.

J Mol Biol. 2016 Aug 14;428(16):3305-24. doi: 10.1016/j.jmb.2016.06.011. Epub 2016 Jun 23. Review.


Mieap-regulated mitochondrial quality control is frequently inactivated in human colorectal cancer.

Kamino H, Nakamura Y, Tsuneki M, Sano H, Miyamoto Y, Kitamura N, Futamura M, Kanai Y, Taniguchi H, Shida D, Kanemitsu Y, Moriya Y, Yoshida K, Arakawa H.

Oncogenesis. 2016 Jan 4;4:e181. doi: 10.1038/oncsis.2015.43.


Bcl-2 family member Mcl-1 expression is reduced under hypoxia by the E3 ligase FBW7 contributing to BNIP3 induced cell death in glioma cells.

Chen Y, Henson ES, Xiao W, Shome E, Azad MB, Burton TR, Queau M, Sathya A, Eisenstat DD, Gibson SB.

Cancer Biol Ther. 2016 Jun 2;17(6):604-13. doi: 10.1080/15384047.2015.1095399. Epub 2015 Oct 15.


Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis.

Chourasia AH, Tracy K, Frankenberger C, Boland ML, Sharifi MN, Drake LE, Sachleben JR, Asara JM, Locasale JW, Karczmar GS, Macleod KF.

EMBO Rep. 2015 Sep;16(9):1145-63. doi: 10.15252/embr.201540759. Epub 2015 Jul 31.


Dysregulation of Mitochondrial Functions and Osteogenic Differentiation in Cisd2-Deficient Murine Induced Pluripotent Stem Cells.

Tsai PH, Chien Y, Chuang JH, Chou SJ, Chien CH, Lai YH, Li HY, Ko YL, Chang YL, Wang CY, Liu YY, Lee HC, Yang CH, Tsai TF, Lee YY, Chiou SH.

Stem Cells Dev. 2015 Nov 1;24(21):2561-76. doi: 10.1089/scd.2015.0066. Epub 2015 Aug 10.


Role of Bcl-2/adenovirus E1B 19 kDa-interacting protein 3 in myocardial cells in diabetes.

Zhou W, Yang J, Zhang DI, Li F, Li G, Gu Y, Luo M.

Exp Ther Med. 2015 Jul;10(1):67-73. Epub 2015 Apr 22.


Phosphorylation of the BNIP3 C-Terminus Inhibits Mitochondrial Damage and Cell Death without Blocking Autophagy.

Liu KE, Frazier WA.

PLoS One. 2015 Jun 23;10(6):e0129667. doi: 10.1371/journal.pone.0129667. eCollection 2015.


LW6, a hypoxia-inducible factor 1 inhibitor, selectively induces apoptosis in hypoxic cells through depolarization of mitochondria in A549 human lung cancer cells.

Sato M, Hirose K, Kashiwakura I, Aoki M, Kawaguchi H, Hatayama Y, Akimoto H, Narita Y, Takai Y.

Mol Med Rep. 2015 Sep;12(3):3462-8. doi: 10.3892/mmr.2015.3862. Epub 2015 May 27.


Transcriptional Response to Acute Thermal Exposure in Juvenile Chinook Salmon Determined by RNAseq.

Tomalty KM, Meek MH, Stephens MR, Rincón G, Fangue NA, May BP, Baerwald MR.

G3 (Bethesda). 2015 Apr 24;5(7):1335-49. doi: 10.1534/g3.115.017699.


Silibinin, a natural flavonoid, induces autophagy via ROS-dependent mitochondrial dysfunction and loss of ATP involving BNIP3 in human MCF7 breast cancer cells.

Jiang K, Wang W, Jin X, Wang Z, Ji Z, Meng G.

Oncol Rep. 2015 Jun;33(6):2711-8. doi: 10.3892/or.2015.3915. Epub 2015 Apr 17.


Mitophagy and cancer.

Chourasia AH, Boland ML, Macleod KF.

Cancer Metab. 2015 Mar 26;3:4. doi: 10.1186/s40170-015-0130-8. eCollection 2015.


Cellular redox status determines sensitivity to BNIP3-mediated cell death in cardiac myocytes.

Lee Y, Kubli DA, Hanna RA, Cortez MQ, Lee HY, Miyamoto S, Gustafsson ÅB.

Am J Physiol Cell Physiol. 2015 Jun 15;308(12):C983-92. doi: 10.1152/ajpcell.00273.2014. Epub 2015 Mar 25.

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