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Structure and Dynamics of DNA and RNA Double Helices of CAG and GAC Trinucleotide Repeats.

Pan F, Man VH, Roland C, Sagui C.

Biophys J. 2017 Jul 11;113(1):19-36. doi: 10.1016/j.bpj.2017.05.041.


The dynamics of early-state transcriptional changes and aggregate formation in a Huntington's disease cell model.

van Hagen M, Piebes DGE, de Leeuw WC, Vuist IM, van Roon-Mom WMC, Moerland PD, Verschure PJ.

BMC Genomics. 2017 May 12;18(1):373. doi: 10.1186/s12864-017-3745-z.


Aggregation landscapes of Huntingtin exon 1 protein fragments and the critical repeat length for the onset of Huntington's disease.

Chen M, Wolynes PG.

Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4406-4411. doi: 10.1073/pnas.1702237114. Epub 2017 Apr 11.


NCLs and ER: A stressful relationship.

Marotta D, Tinelli E, Mole SE.

Biochim Biophys Acta. 2017 Jun;1863(6):1273-1281. doi: 10.1016/j.bbadis.2017.04.003. Epub 2017 Apr 6. Review.


Drosophila melanogaster As a Model Organism to Study RNA Toxicity of Repeat Expansion-Associated Neurodegenerative and Neuromuscular Diseases.

Koon AC, Chan HY.

Front Cell Neurosci. 2017 Mar 21;11:70. doi: 10.3389/fncel.2017.00070. eCollection 2017. Review.


The Protein Structure Context of PolyQ Regions.

Totzeck F, Andrade-Navarro MA, Mier P.

PLoS One. 2017 Jan 26;12(1):e0170801. doi: 10.1371/journal.pone.0170801. eCollection 2017.


Thermodynamic and kinetic stability of the Josephin Domain closed arrangement: evidences from replica exchange molecular dynamics.

Grasso G, Tuszynski JA, Morbiducci U, Licandro G, Danani A, Deriu MA.

Biol Direct. 2017 Jan 19;12(1):2. doi: 10.1186/s13062-016-0173-y.


Dysregulation of Ubiquitin-Proteasome System in Neurodegenerative Diseases.

Zheng Q, Huang T, Zhang L, Zhou Y, Luo H, Xu H, Wang X.

Front Aging Neurosci. 2016 Dec 15;8:303. doi: 10.3389/fnagi.2016.00303. eCollection 2016. Review.


Drosophila ataxin-2 gene encodes two differentially expressed isoforms and its function in larval fat body is crucial for development of peripheral tissues.

Vianna MC, Poleto DC, Gomes PF, Valente V, Paçó-Larson ML.

FEBS Open Bio. 2016 Oct 7;6(11):1040-1053. eCollection 2016 Nov.


Distinct patterns of simple sequence repeats and GC distribution in intragenic and intergenic regions of primate genomes.

Qi WH, Yan CC, Li WJ, Jiang XM, Li GZ, Zhang XY, Hu TZ, Li J, Yue BS.

Aging (Albany NY). 2016 Sep 16;8(11):2635-2654. doi: 10.18632/aging.101025.


The cellular basis of dendrite pathology in neurodegenerative diseases.

Kweon JH, Kim S, Lee SB.

BMB Rep. 2017 Jan;50(1):5-11. Review.


Nanoscale studies link amyloid maturity with polyglutamine diseases onset.

Ruggeri FS, Vieweg S, Cendrowska U, Longo G, Chiki A, Lashuel HA, Dietler G.

Sci Rep. 2016 Aug 8;6:31155. doi: 10.1038/srep31155.


Glycogen synthase kinase 3β suppresses polyglutamine aggregation by inhibiting Vaccinia-related kinase 2 activity.

Lee E, Ryu HG, Kim S, Lee D, Jeong YH, Kim KT.

Sci Rep. 2016 Jul 5;6:29097. doi: 10.1038/srep29097.



Verkhratsky A, Zorec R, Rodriguez JJ, Parpura V.

Opera Med Physiol. 2016 Jan;1:13-22. Epub 2016 Mar 4.


Sequence Context Influences the Structure and Aggregation Behavior of a PolyQ Tract.

Eftekharzadeh B, Piai A, Chiesa G, Mungianu D, García J, Pierattelli R, Felli IC, Salvatella X.

Biophys J. 2016 Jun 7;110(11):2361-6. doi: 10.1016/j.bpj.2016.04.022.


AFM-Based Single Molecule Techniques: Unraveling the Amyloid Pathogenic Species.

Ruggeri FS, Habchi J, Cerreta A, Dietler G.

Curr Pharm Des. 2016;22(26):3950-70.


The 2.2-Angstrom resolution crystal structure of the carboxy-terminal region of ataxin-3.

Zhemkov VA, Kulminskaya AA, Bezprozvanny IB, Kim M.

FEBS Open Bio. 2016 Feb 18;6(3):168-78. doi: 10.1002/2211-5463.12029. eCollection 2016 Mar.


Free-Energy Landscape of the Amino-Terminal Fragment of Huntingtin in Aqueous Solution.

Binette V, Côté S, Mousseau N.

Biophys J. 2016 Mar 8;110(5):1075-88. doi: 10.1016/j.bpj.2016.01.015.


Endoplasmic Reticulum Stress and Associated ROS.

Zeeshan HM, Lee GH, Kim HR, Chae HJ.

Int J Mol Sci. 2016 Mar 2;17(3):327. doi: 10.3390/ijms17030327. Review.


Precision medicine in spinocerebellar ataxias: treatment based on common mechanisms of disease.

Bushart DD, Murphy GG, Shakkottai VG.

Ann Transl Med. 2016 Jan;4(2):25. doi: 10.3978/j.issn.2305-5839.2016.01.06. Review.

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