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Circulating tumor cell clusters-associated gene plakoglobin is a significant prognostic predictor in patients with breast cancer.

Goto W, Kashiwagi S, Asano Y, Takada K, Takahashi K, Hatano T, Takashima T, Tomita S, Motomura H, Ohsawa M, Hirakawa K, Ohira M.

Biomark Res. 2017 May 12;5:19. doi: 10.1186/s40364-017-0099-2. eCollection 2017.


Beyond cell-cell adhesion: Plakoglobin and the regulation of tumorigenesis and metastasis.

Aktary Z, Alaee M, Pasdar M.

Oncotarget. 2017 May 9;8(19):32270-32291. doi: 10.18632/oncotarget.15650. Review.


β-Catenin haploinsufficiency promotes mammary tumorigenesis in an ErbB2-positive basal breast cancer model.

Tung B, Schade B, Cardiff RD, Aina OH, Sanguin-Gendreau V, Muller WJ.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E707-E716. doi: 10.1073/pnas.1610383114. Epub 2017 Jan 17. Erratum in: Proc Natl Acad Sci U S A. 2017 Feb 27;:. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2265.


Depletion of γ-catenin by Histone Deacetylase Inhibition Confers Elimination of CML Stem Cells in Combination with Imatinib.

Jin Y, Yao Y, Chen L, Zhu X, Jin B, Shen Y, Li J, Du X, Lu Y, Jiang S, Pan J.

Theranostics. 2016 Aug 12;6(11):1947-62. doi: 10.7150/thno.16139. eCollection 2016.


The expression of plakoglobin is a potential prognostic biomarker for patients with surgically resected lung adenocarcinoma.

He X, Zhou T, Yang G, Fang W, Li Z, Zhan J, Zhao Y, Cheng Z, Huang Y, Zhao H, Zhang L.

Oncotarget. 2016 Mar 22;7(12):15274-87. doi: 10.18632/oncotarget.7729.


Mice with Hepatic Loss of the Desmosomal Protein γ-Catenin Are Prone to Cholestatic Injury and Chemical Carcinogenesis.

Zhou L, Pradhan-Sundd T, Poddar M, Singh S, Kikuchi A, Stolz DB, Shou W, Li Z, Nejak-Bowen KN, Monga SP.

Am J Pathol. 2015 Dec;185(12):3274-89. doi: 10.1016/j.ajpath.2015.08.019. Epub 2015 Oct 17.


Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis.

Aceto N, Bardia A, Miyamoto DT, Donaldson MC, Wittner BS, Spencer JA, Yu M, Pely A, Engstrom A, Zhu H, Brannigan BW, Kapur R, Stott SL, Shioda T, Ramaswamy S, Ting DT, Lin CP, Toner M, Haber DA, Maheswaran S.

Cell. 2014 Aug 28;158(5):1110-22. doi: 10.1016/j.cell.2014.07.013.


DSG3 facilitates cancer cell growth and invasion through the DSG3-plakoglobin-TCF/LEF-Myc/cyclin D1/MMP signaling pathway.

Chen YJ, Lee LY, Chao YK, Chang JT, Lu YC, Li HF, Chiu CC, Li YC, Li YL, Chiou JF, Cheng AJ.

PLoS One. 2013 May 30;8(5):e64088. doi: 10.1371/journal.pone.0064088. Print 2013.


Ectopic γ-catenin expression partially mimics the effects of stabilized β-catenin on embryonic stem cell differentiation.

Mahendram S, Kelly KF, Paez-Parent S, Mahmood S, Polena E, Cooney AJ, Doble BW.

PLoS One. 2013 May 27;8(5):e65320. doi: 10.1371/journal.pone.0065320. Print 2013.


Wnt/beta-catenin signaling and small molecule inhibitors.

Voronkov A, Krauss S.

Curr Pharm Des. 2013;19(4):634-64. Review.


γ-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of β-catenin.

Morgan RG, Pearn L, Liddiard K, Pumford SL, Burnett AK, Tonks A, Darley RL.

Leukemia. 2013 Feb;27(2):336-43. doi: 10.1038/leu.2012.221. Epub 2012 Aug 3.


Activation of multiple cancer pathways and tumor maintenance function of the 3q amplified oncogene FNDC3B.

Cai C, Rajaram M, Zhou X, Liu Q, Marchica J, Li J, Powers RS.

Cell Cycle. 2012 May 1;11(9):1773-81. doi: 10.4161/cc.20121. Epub 2012 May 1.


Plakoglobin: role in tumorigenesis and metastasis.

Aktary Z, Pasdar M.

Int J Cell Biol. 2012;2012:189521. doi: 10.1155/2012/189521. Epub 2012 Mar 8.


Expression of DSG1 and DSC1 are prognostic markers in anal carcinoma patients.

Myklebust MP, Fluge Ø, Immervoll H, Skarstein A, Balteskard L, Bruland O, Dahl O.

Br J Cancer. 2012 Feb 14;106(4):756-62. doi: 10.1038/bjc.2011.548.


SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells.

Lai YH, Cheng J, Cheng D, Feasel ME, Beste KD, Peng J, Nusrat A, Moreno CS.

BMC Cell Biol. 2011 Nov 19;12:50. doi: 10.1186/1471-2121-12-50.


Cell-cell contact preserves cell viability via plakoglobin.

Wei Q, Hariharan V, Huang H.

PLoS One. 2011;6(10):e27064. doi: 10.1371/journal.pone.0027064. Epub 2011 Oct 28.


Desmosomes: new perpetrators in tumour suppression.

Dusek RL, Attardi LD.

Nat Rev Cancer. 2011 May;11(5):317-23. doi: 10.1038/nrc3051. Review.


Diverse mechanisms of Wnt activation and effects of pathway inhibition on proliferation of human gastric carcinoma cells.

Asciutti S, Akiri G, Grumolato L, Vijayakumar S, Aaronson SA.

Oncogene. 2011 Feb 24;30(8):956-66. doi: 10.1038/onc.2010.475. Epub 2010 Nov 1.


The Prognostic Impact of Protein Expression of E-Cadherin-Catenin Complexes Differs between Rectal and Colon Carcinoma.

Aamodt R, Bondi J, Andersen SN, Bakka A, Bukholm G, Bukholm IR.

Gastroenterol Res Pract. 2010;2010. pii: 616023. doi: 10.1155/2010/616023. Epub 2010 Aug 16.

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