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Items: 1 to 20 of 238

1.

Biological function of Lemur tyrosine kinase 2 (LMTK2): implications in neurodegeneration.

Bencze J, Mórotz GM, Seo W, Bencs V, Kálmán J, Miller CCJ, Hortobágyi T.

Mol Brain. 2018 Apr 10;11(1):20. doi: 10.1186/s13041-018-0363-x. Review.

2.

Melatonin Mitigates Kainic Acid-Induced Neuronal Tau Hyperphosphorylation and Memory Deficits through Alleviating ER Stress.

Shi C, Zeng J, Li Z, Chen Q, Hang W, Xia L, Wu Y, Chen J, Shi A.

Front Mol Neurosci. 2018 Jan 24;11:5. doi: 10.3389/fnmol.2018.00005. eCollection 2018.

3.

Inhibition of cyclin-dependent kinase 5 affects early neuroinflammatory signalling in murine model of amyloid beta toxicity.

Wilkaniec A, Gąssowska-Dobrowolska M, Strawski M, Adamczyk A, Czapski GA.

J Neuroinflammation. 2018 Jan 4;15(1):1. doi: 10.1186/s12974-017-1027-y.

4.

Hippocampal calpain is required for the consolidation and reconsolidation but not extinction of contextual fear memory.

Nagayoshi T, Isoda K, Mamiya N, Kida S.

Mol Brain. 2017 Dec 19;10(1):61. doi: 10.1186/s13041-017-0341-8.

5.

Stress-induced Cdk5 activity enhances cytoprotective basal autophagy in Drosophila melanogaster by phosphorylating acinus at serine437.

Nandi N, Tyra LK, Stenesen D, Krämer H.

Elife. 2017 Dec 11;6. pii: e30760. doi: 10.7554/eLife.30760.

6.

Cdk5 Is Essential for Amphetamine to Increase Dendritic Spine Density in Hippocampal Pyramidal Neurons.

Ferreras S, Fernández G, Danelon V, Pisano MV, Masseroni L, Chapleau CA, Krapacher FA, Mlewski EC, Mascó DH, Arias C, Pozzo-Miller L, Paglini MG.

Front Cell Neurosci. 2017 Nov 24;11:372. doi: 10.3389/fncel.2017.00372. eCollection 2017.

7.

Expression of Tau Pathology-Related Proteins in Different Brain Regions: A Molecular Basis of Tau Pathogenesis.

Hu W, Wu F, Zhang Y, Gong CX, Iqbal K, Liu F.

Front Aging Neurosci. 2017 Sep 27;9:311. doi: 10.3389/fnagi.2017.00311. eCollection 2017.

8.

The tyrosine phosphatase PTPN13/FAP-1 links calpain-2, TBI and tau tyrosine phosphorylation.

Wang Y, Hall RA, Lee M, Kamgar-Parsi A, Bi X, Baudry M.

Sci Rep. 2017 Sep 18;7(1):11771. doi: 10.1038/s41598-017-12236-3.

9.

Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia.

Seo J, Kritskiy O, Watson LA, Barker SJ, Dey D, Raja WK, Lin YT, Ko T, Cho S, Penney J, Silva MC, Sheridan SD, Lucente D, Gusella JF, Dickerson BC, Haggarty SJ, Tsai LH.

J Neurosci. 2017 Oct 11;37(41):9917-9924. doi: 10.1523/JNEUROSCI.0621-17.2017. Epub 2017 Sep 14.

10.

Physiological Concentrations of Amyloid Beta Regulate Recycling of Synaptic Vesicles via Alpha7 Acetylcholine Receptor and CDK5/Calcineurin Signaling.

Lazarevic V, Fieńko S, Andres-Alonso M, Anni D, Ivanova D, Montenegro-Venegas C, Gundelfinger ED, Cousin MA, Fejtova A.

Front Mol Neurosci. 2017 Jul 21;10:221. doi: 10.3389/fnmol.2017.00221. eCollection 2017.

11.

Characterization of the CDK5 gene in Apis cerana cerana (AccCDK5) and a preliminary identification of its activator gene, AccCDK5r1.

Zhao G, Wang C, Wang H, Gao L, Liu Z, Xu B, Guo X.

Cell Stress Chaperones. 2018 Jan;23(1):13-28. doi: 10.1007/s12192-017-0820-y. Epub 2017 Jul 3.

PMID:
28674940
12.

Tau secretion is correlated to an increase of Golgi dynamics.

Mohamed NV, Desjardins A, Leclerc N.

PLoS One. 2017 May 26;12(5):e0178288. doi: 10.1371/journal.pone.0178288. eCollection 2017.

13.

Chronic diabetic states worsen Alzheimer neuropathology and cognitive deficits accompanying disruption of calcium signaling in leptin-deficient APP/PS1 mice.

Zhang S, Chai R, Yang YY, Guo SQ, Wang S, Guo T, Xu SF, Zhang YH, Wang ZY, Guo C.

Oncotarget. 2017 Jul 4;8(27):43617-43634. doi: 10.18632/oncotarget.17116.

14.

Calcium dysregulation and Cdk5-ATM pathway involved in a mouse model of fragile X-associated tremor/ataxia syndrome.

Robin G, López JR, Espinal GM, Hulsizer S, Hagerman PJ, Pessah IN.

Hum Mol Genet. 2017 Jul 15;26(14):2649-2666. doi: 10.1093/hmg/ddx148.

PMID:
28444183
15.

Cdk5 links with DNA damage response and cancer.

Liu W, Li J, Song YS, Li Y, Jia YH, Zhao HD.

Mol Cancer. 2017 Mar 14;16(1):60. doi: 10.1186/s12943-017-0611-1. Review.

16.

Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research?

De Vos KJ, Hafezparast M.

Neurobiol Dis. 2017 Sep;105:283-299. doi: 10.1016/j.nbd.2017.02.004. Epub 2017 Feb 22. Review.

17.

Cyclin I-like (CCNI2) is a cyclin-dependent kinase 5 (CDK5) activator and is involved in cell cycle regulation.

Liu C, Zhai X, Zhao B, Wang Y, Xu Z.

Sci Rep. 2017 Jan 23;7:40979. doi: 10.1038/srep40979.

18.

Neuronal Cell Death and Degeneration through Increased Nitroxidative Stress and Tau Phosphorylation in HIV-1 Transgenic Rats.

Cho YE, Lee MH, Song BJ.

PLoS One. 2017 Jan 20;12(1):e0169945. doi: 10.1371/journal.pone.0169945. eCollection 2017.

19.

Special Issue on "Cdk5 and Brain Disorders": Prologue.

Kanungo J.

Brain Disord Ther. 2012;Suppl 1. pii: e001. Epub 2012 May 31.

20.

Early Cytoskeletal Protein Modifications Precede Overt Structural Degeneration in the DBA/2J Mouse Model of Glaucoma.

Wilson GN, Smith MA, Inman DM, Dengler-Crish CM, Crish SD.

Front Neurosci. 2016 Nov 3;10:494. eCollection 2016.

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