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Items: 1 to 20 of 32

1.

Hedgehog Cholesterolysis: Specialized Gatekeeper to Oncogenic Signaling.

Callahan BP, Wang C.

Cancers (Basel). 2015 Oct 14;7(4):2037-53. doi: 10.3390/cancers7040875. Review.

2.

Branching out of the intein active site in protein splicing.

Callahan BP, Belfort M.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8323-4. doi: 10.1073/pnas.1407116111. Epub 2014 May 28. No abstract available.

3.

Structural and dynamical features of inteins and implications on protein splicing.

Eryilmaz E, Shah NH, Muir TW, Cowburn D.

J Biol Chem. 2014 May 23;289(21):14506-11. doi: 10.1074/jbc.R113.540302. Epub 2014 Apr 2. Review.

4.

Protein splicing: how inteins escape from precursor proteins.

Mills KV, Johnson MA, Perler FB.

J Biol Chem. 2014 May 23;289(21):14498-505. doi: 10.1074/jbc.R113.540310. Epub 2014 Apr 2. Review.

5.

Chemistry of bridged lactams and related heterocycles.

Szostak M, Aubé J.

Chem Rev. 2013 Aug 14;113(8):5701-65. doi: 10.1021/cr4000144. Epub 2013 Jun 17. Review. No abstract available.

6.

Analysis of inteins in the Candida parapsilosis complex for simple and accurate species identification.

Prandini TH, Theodoro RC, Bruder-Nascimento AC, Scheel CM, Bagagli E.

J Clin Microbiol. 2013 Sep;51(9):2830-6. doi: 10.1128/JCM.00981-13. Epub 2013 Jun 19.

7.

A conserved threonine spring-loads precursor for intein splicing.

Dearden AK, Callahan B, Roey PV, Li Z, Kumar U, Belfort M, Nayak SK.

Protein Sci. 2013 May;22(5):557-63. doi: 10.1002/pro.2236. Epub 2013 Mar 26.

8.

A predictive model of intein insertion site for use in the engineering of molecular switches.

Apgar J, Ross M, Zuo X, Dohle S, Sturtevant D, Shen B, de la Vega H, Lessard P, Lazar G, Raab RM.

PLoS One. 2012;7(5):e37355. doi: 10.1371/journal.pone.0037355. Epub 2012 May 23.

9.

NMR and crystal structures of the Pyrococcus horikoshii RadA intein guide a strategy for engineering a highly efficient and promiscuous intein.

Oeemig JS, Zhou D, Kajander T, Wlodawer A, Iwaï H.

J Mol Biol. 2012 Aug 3;421(1):85-99. doi: 10.1016/j.jmb.2012.04.029. Epub 2012 May 2.

10.

Intramolecular disulfide bond between catalytic cysteines in an intein precursor.

Chen W, Li L, Du Z, Liu J, Reitter JN, Mills KV, Linhardt RJ, Wang C.

J Am Chem Soc. 2012 Feb 8;134(5):2500-3. doi: 10.1021/ja211010g. Epub 2012 Jan 27.

11.

Structural and mutational studies of a hyperthermophilic intein from DNA polymerase II of Pyrococcus abyssi.

Du Z, Liu J, Albracht CD, Hsu A, Chen W, Marieni MD, Colelli KM, Williams JE, Reitter JN, Mills KV, Wang C.

J Biol Chem. 2011 Nov 4;286(44):38638-48. doi: 10.1074/jbc.M111.290569. Epub 2011 Sep 13.

12.

Covalent inhibitors of fatty acid amide hydrolase: a rationale for the activity of piperidine and piperazine aryl ureas.

Palermo G, Branduardi D, Masetti M, Lodola A, Mor M, Piomelli D, Cavalli A, De Vivo M.

J Med Chem. 2011 Oct 13;54(19):6612-23. doi: 10.1021/jm2004283. Epub 2011 Sep 8.

13.

Electronic structure of neighboring extein residue modulates intein C-terminal cleavage activity.

Shemella PT, Topilina NI, Soga I, Pereira B, Belfort G, Belfort M, Nayak SK.

Biophys J. 2011 May 4;100(9):2217-25. doi: 10.1016/j.bpj.2011.02.037.

14.

Structure of catalytically competent intein caught in a redox trap with functional and evolutionary implications.

Callahan BP, Topilina NI, Stanger MJ, Van Roey P, Belfort M.

Nat Struct Mol Biol. 2011 May;18(5):630-3. doi: 10.1038/nsmb.2041. Epub 2011 Apr 3.

15.

Structural characterization of N-protonated amides: regioselective N-activation of medium-bridged twisted lactams.

Szostak M, Yao L, Day VW, Powell DR, Aubé J.

J Am Chem Soc. 2010 Jul 7;132(26):8836-7. doi: 10.1021/ja101690u.

16.

Branched intermediate formation stimulates peptide bond cleavage in protein splicing.

Frutos S, Goger M, Giovani B, Cowburn D, Muir TW.

Nat Chem Biol. 2010 Jul;6(7):527-33. doi: 10.1038/nchembio.371. Epub 2010 May 23.

17.

Reflections on protein splicing: structures, functions and mechanisms.

Anraku Y, Satow Y.

Proc Jpn Acad Ser B Phys Biol Sci. 2009;85(9):409-21. Review.

18.

Highly conserved histidine plays a dual catalytic role in protein splicing: a pKa shift mechanism.

Du Z, Shemella PT, Liu Y, McCallum SA, Pereira B, Nayak SK, Belfort G, Belfort M, Wang C.

J Am Chem Soc. 2009 Aug 19;131(32):11581-9. doi: 10.1021/ja904318w.

19.

Metal ions binding to recA inteins from Mycobacterium tuberculosis.

Zhang L, Zheng Y, Xi Z, Luo Z, Xu X, Wang C, Liu Y.

Mol Biosyst. 2009 Jun;5(6):644-50. doi: 10.1039/b903144h. Epub 2009 Apr 21.

20.

Structural constraints on autoprocessing of the human nucleoporin Nup98.

Sun Y, Guo HC.

Protein Sci. 2008 Mar;17(3):494-505. doi: 10.1110/ps.073311808.

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