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Items: 1 to 20 of 119

1.

The FcεRI Signaling Cascade and Integrin Trafficking Converge at Patterned Ligand Surfaces.

Wakefield DL, Holowka D, Baird B.

Mol Biol Cell. 2017 Aug 9. pii: mbc.E17-03-0208. doi: 10.1091/mbc.E17-03-0208. [Epub ahead of print]

PMID:
28794269
2.

LFA-1 activates focal adhesion kinases FAK1/PYK2 to generate LAT-GRB2-SKAP1 complexes that terminate T-cell conjugate formation.

Raab M, Lu Y, Kohler K, Smith X, Strebhardt K, Rudd CE.

Nat Commun. 2017 Jul 12;8:16001. doi: 10.1038/ncomms16001.

3.

The human cytomegalovirus glycoprotein pUL11 acts via CD45 to induce T cell IL-10 secretion.

Zischke J, Mamareli P, Pokoyski C, Gabaev I, Buyny S, Jacobs R, Falk CS, Lochner M, Sparwasser T, Schulz TF, Kay-Fedorov PC.

PLoS Pathog. 2017 Jun 19;13(6):e1006454. doi: 10.1371/journal.ppat.1006454. eCollection 2017 Jun.

4.

Molecular mechanisms underlying the evolution of the slp76 signalosome.

Qu X, Lan X, Deng C, Zhou J, Du J, Huang S, Li Y.

Sci Rep. 2017 May 4;7(1):1509. doi: 10.1038/s41598-017-01660-0.

5.

Reconstitution of TCR Signaling Using Supported Lipid Bilayers.

Su X, Ditlev JA, Rosen MK, Vale RD.

Methods Mol Biol. 2017;1584:65-76. doi: 10.1007/978-1-4939-6881-7_5.

PMID:
28255696
6.

Cbl ubiquitin ligases mediate the inhibition of natural killer cell activity.

Matalon O, Barda-Saad M.

Commun Integr Biol. 2016 Sep 8;9(6):e1216739. doi: 10.1080/19420889.2016.1216739. eCollection 2016.

7.

Phospholipase Cγ1 is required for pre-TCR signal transduction and pre-T cell development.

Fu G, Yu M, Chen Y, Zheng Y, Zhu W, Newman DK, Wang D, Wen R.

Eur J Immunol. 2017 Jan;47(1):74-83. doi: 10.1002/eji.201646522. Epub 2016 Nov 7.

8.

Cell-based phenotypic screening of mast cell degranulation unveils kinetic perturbations of agents targeting phosphorylation.

Qin S, Wang X, Wu H, Xiao P, Cheng H, Zhang X, Ke Y.

Sci Rep. 2016 Aug 9;6:31320. doi: 10.1038/srep31320.

9.

Glycerol Monolaurate (GML) inhibits human T cell signaling and function by disrupting lipid dynamics.

Zhang MS, Sandouk A, Houtman JC.

Sci Rep. 2016 Jul 26;6:30225. doi: 10.1038/srep30225.

10.

CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice.

Poissonnier A, Sanséau D, Le Gallo M, Malleter M, Levoin N, Viel R, Morere L, Penna A, Blanco P, Dupuy A, Poizeau F, Fautrel A, Seneschal J, Jouan F, Ritz J, Forcade E, Rioux N, Contin-Bordes C, Ducret T, Vacher AM, Barrow PA, Flynn RJ, Vacher P, Legembre P.

Immunity. 2016 Jul 19;45(1):209-23. doi: 10.1016/j.immuni.2016.06.028.

11.

Hierarchical nanostructure and synergy of multimolecular signalling complexes.

Sherman E, Barr VA, Merrill RK, Regan CK, Sommers CL, Samelson LE.

Nat Commun. 2016 Jul 11;7:12161. doi: 10.1038/ncomms12161.

12.

Molecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling Units.

Wehbi VL, Taskén K.

Front Immunol. 2016 Jun 8;7:222. doi: 10.3389/fimmu.2016.00222. eCollection 2016. Review.

13.

Early onset combined immunodeficiency and autoimmunity in patients with loss-of-function mutation in LAT.

Keller B, Zaidman I, Yousefi OS, Hershkovitz D, Stein J, Unger S, Schachtrup K, Sigvardsson M, Kuperman AA, Shaag A, Schamel WW, Elpeleg O, Warnatz K, Stepensky P.

J Exp Med. 2016 Jun 27;213(7):1185-99. doi: 10.1084/jem.20151110. Epub 2016 May 30. Erratum in: J Exp Med. 2017 Jun 1;:.

14.

The linker for activation of T cells (LAT) signaling hub: from signaling complexes to microclusters.

Balagopalan L, Kortum RL, Coussens NP, Barr VA, Samelson LE.

J Biol Chem. 2015 Oct 30;290(44):26422-9. doi: 10.1074/jbc.R115.665869. Epub 2015 Sep 9. Review.

15.

Vav1 Regulates T-Cell Activation through a Feedback Mechanism and Crosstalk between the T-Cell Receptor and CD28.

Helou YA, Petrashen AP, Salomon AR.

J Proteome Res. 2015 Jul 2;14(7):2963-75. doi: 10.1021/acs.jproteome.5b00340. Epub 2015 Jun 16.

16.

The Importance of IL-6 in the Development of LAT-Mediated Autoimmunity.

O'Brien SA, Zhu M, Zhang W.

J Immunol. 2015 Jul 15;195(2):695-705. doi: 10.4049/jimmunol.1403187. Epub 2015 Jun 1.

17.

GRB2 Nucleates T Cell Receptor-Mediated LAT Clusters That Control PLC-γ1 Activation and Cytokine Production.

Bilal MY, Houtman JC.

Front Immunol. 2015 Mar 30;6:141. doi: 10.3389/fimmu.2015.00141. eCollection 2015.

18.

Phosphorylation site dynamics of early T-cell receptor signaling.

Chylek LA, Akimov V, Dengjel J, Rigbolt KT, Hu B, Hlavacek WS, Blagoev B.

PLoS One. 2014 Aug 22;9(8):e104240. doi: 10.1371/journal.pone.0104240. eCollection 2014.

19.

The combined loss of Gads and CD127 reveals a novel function of Gads prior to TCRβ expression.

Xiong J, Parker BL, Yankee TM.

Immunol Res. 2014 Oct;60(1):77-84. doi: 10.1007/s12026-014-8556-6.

20.

The role of LAT-PLCγ1 interaction in γδ T cell development and homeostasis.

Sullivan SA, Zhu M, Bao S, Lewis CA, Ou-Yang CW, Zhang W.

J Immunol. 2014 Mar 15;192(6):2865-74. doi: 10.4049/jimmunol.1302493. Epub 2014 Feb 12.

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