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Items: 1 to 20 of 50

1.

Promoter methylation of DNA damage repair (DDR) genes in human tumor entities: RBBP8/CtIP is almost exclusively methylated in bladder cancer.

Mijnes J, Veeck J, Gaisa NT, Burghardt E, de Ruijter TC, Gostek S, Dahl E, Pfister D, Schmid SC, Knüchel R, Rose M.

Clin Epigenetics. 2018 Feb 6;10:15. doi: 10.1186/s13148-018-0447-6. eCollection 2018.

2.

H4K20me2 distinguishes pre-replicative from post-replicative chromatin to appropriately direct DNA repair pathway choice by 53BP1-RIF1-MAD2L2.

Simonetta M, de Krijger I, Serrat J, Moatti N, Fortunato D, Hoekman L, Bleijerveld OB, Altelaar AFM, Jacobs JJL.

Cell Cycle. 2018;17(1):124-136. doi: 10.1080/15384101.2017.1404210. Epub 2018 Jan 2.

PMID:
29160738
3.

FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response.

Thompson EL, Yeo JE, Lee EA, Kan Y, Raghunandan M, Wiek C, Hanenberg H, Schärer OD, Hendrickson EA, Sobeck A.

Nucleic Acids Res. 2017 Nov 16;45(20):11837-11857. doi: 10.1093/nar/gkx847.

4.

SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.

Daddacha W, Koyen AE, Bastien AJ, Head PE, Dhere VR, Nabeta GN, Connolly EC, Werner E, Madden MZ, Daly MB, Minten EV, Whelan DR, Schlafstein AJ, Zhang H, Anand R, Doronio C, Withers AE, Shepard C, Sundaram RK, Deng X, Dynan WS, Wang Y, Bindra RS, Cejka P, Rothenberg E, Doetsch PW, Kim B, Yu DS.

Cell Rep. 2017 Aug 22;20(8):1921-1935. doi: 10.1016/j.celrep.2017.08.008.

5.

Structural basis to stabilize the domain motion of BARD1-ARD BRCT by CstF50.

Choudhary RK, Siddiqui MQ, Thapa PS, Gadewal N, Nachimuthu SK, Varma AK.

Sci Rep. 2017 Jun 20;7(1):3849. doi: 10.1038/s41598-017-03816-4.

6.

Cullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resection.

Ferretti LP, Himmels SF, Trenner A, Walker C, von Aesch C, Eggenschwiler A, Murina O, Enchev RI, Peter M, Freire R, Porro A, Sartori AA.

Nat Commun. 2016 Aug 26;7:12628. doi: 10.1038/ncomms12628.

7.

The DNA resection protein CtIP promotes mammary tumorigenesis.

Reczek CR, Shakya R, Miteva Y, Szabolcs M, Ludwig T, Baer R.

Oncotarget. 2016 May 31;7(22):32172-83. doi: 10.18632/oncotarget.8605.

9.

MRN, CtIP, and BRCA1 mediate repair of topoisomerase II-DNA adducts.

Aparicio T, Baer R, Gottesman M, Gautier J.

J Cell Biol. 2016 Feb 15;212(4):399-408. doi: 10.1083/jcb.201504005.

10.

Loss of CtIP disturbs homologous recombination repair and sensitizes breast cancer cells to PARP inhibitors.

Wang J, Ding Q, Fujimori H, Motegi A, Miki Y, Masutani M.

Oncotarget. 2016 Feb 16;7(7):7701-14. doi: 10.18632/oncotarget.6715.

11.

Pathways for genome integrity in G2 phase of the cell cycle.

Kousholt AN, Menzel T, Sørensen CS.

Biomolecules. 2012 Nov 30;2(4):579-607. doi: 10.3390/biom2040579. Erratum in: Biomolecules. 2013;3(1):72-4.

12.

BRCA1 and Oxidative Stress.

Yi YW, Kang HJ, Bae I.

Cancers (Basel). 2014 Apr 3;6(2):771-95. doi: 10.3390/cancers6020771.

13.

CtIP mediates replication fork recovery in a FANCD2-regulated manner.

Yeo JE, Lee EH, Hendrickson EA, Sobeck A.

Hum Mol Genet. 2014 Jul 15;23(14):3695-705. doi: 10.1093/hmg/ddu078. Epub 2014 Feb 20.

14.

Cdk1-dependent regulation of the Mre11 complex couples DNA repair pathways to cell cycle progression.

Simoneau A, Robellet X, Ladouceur AM, D'Amours D.

Cell Cycle. 2014;13(7):1078-90. doi: 10.4161/cc.27946. Epub 2014 Feb 6.

15.

Prognostic value of CtIP/RBBP8 expression in breast cancer.

Soria-Bretones I, Sáez C, Ruíz-Borrego M, Japón MA, Huertas P.

Cancer Med. 2013 Dec;2(6):774-83. doi: 10.1002/cam4.141. Epub 2013 Oct 3.

16.

The interaction between CtIP and BRCA1 is not essential for resection-mediated DNA repair or tumor suppression.

Reczek CR, Szabolcs M, Stark JM, Ludwig T, Baer R.

J Cell Biol. 2013 May 27;201(5):693-707. doi: 10.1083/jcb.201302145.

17.

The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair.

Wang H, Shi LZ, Wong CC, Han X, Hwang PY, Truong LN, Zhu Q, Shao Z, Chen DJ, Berns MW, Yates JR 3rd, Chen L, Wu X.

PLoS Genet. 2013;9(2):e1003277. doi: 10.1371/journal.pgen.1003277. Epub 2013 Feb 28.

18.

Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching.

Bothmer A, Rommel PC, Gazumyan A, Polato F, Reczek CR, Muellenbeck MF, Schaetzlein S, Edelmann W, Chen PL, Brosh RM Jr, Casellas R, Ludwig T, Baer R, Nussenzweig A, Nussenzweig MC, Robbiani DF.

J Exp Med. 2013 Jan 14;210(1):115-23. doi: 10.1084/jem.20121975. Epub 2012 Dec 17.

19.

CtIP is required to initiate replication-dependent interstrand crosslink repair.

Duquette ML, Zhu Q, Taylor ER, Tsay AJ, Shi LZ, Berns MW, McGowan CH.

PLoS Genet. 2012;8(11):e1003050. doi: 10.1371/journal.pgen.1003050. Epub 2012 Nov 8.

20.

MutSβ and histone deacetylase complexes promote expansions of trinucleotide repeats in human cells.

Gannon AM, Frizzell A, Healy E, Lahue RS.

Nucleic Acids Res. 2012 Nov 1;40(20):10324-33. doi: 10.1093/nar/gks810. Epub 2012 Aug 31.

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