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Items: 1 to 20 of 24

1.

Expression profiles of cholesterol metabolism-related genes are altered during development of experimental autoimmune encephalomyelitis in the rat spinal cord.

Lavrnja I, Smiljanic K, Savic D, Mladenovic-Djordjevic A, Tesovic K, Kanazir S, Pekovic S.

Sci Rep. 2017 Jun 2;7(1):2702. doi: 10.1038/s41598-017-02638-8.

2.

Zinc Fingers and Homeoboxes 2 (Zhx2) Regulates Sexually Dimorphic Cyp Gene Expression in the Adult Mouse Liver.

Creasy KT, Jiang J, Ren H, Peterson ML, Spear BT.

Gene Expr. 2016;17(1):7-17. doi: 10.3727/105221616X691712. Epub 2016 May 17.

3.

Obesity is associated with changes in oxysterol metabolism and levels in mice liver, hypothalamus, adipose tissue and plasma.

Guillemot-Legris O, Mutemberezi V, Cani PD, Muccioli GG.

Sci Rep. 2016 Jan 22;6:19694. doi: 10.1038/srep19694.

4.

Impact of physiological levels of chenodeoxycholic acid supplementation on intestinal and hepatic bile acid and cholesterol metabolism in Cyp7a1-deficient mice.

Jones RD, Lopez AM, Tong EY, Posey KS, Chuang JC, Repa JJ, Turley SD.

Steroids. 2015 Jan;93:87-95. doi: 10.1016/j.steroids.2014.11.002. Epub 2014 Nov 28.

5.

Epigenetic regulation of cholesterol homeostasis.

Meaney S.

Front Genet. 2014 Sep 24;5:311. doi: 10.3389/fgene.2014.00311. eCollection 2014. Review.

6.

Genetic, anatomic, and clinical determinants of human serum sterol and vitamin D levels.

Stiles AR, Kozlitina J, Thompson BM, McDonald JG, King KS, Russell DW.

Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):E4006-14. doi: 10.1073/pnas.1413561111. Epub 2014 Sep 8.

7.

The mechanism of enterohepatic circulation in the formation of gallstone disease.

Cai JS, Chen JH.

J Membr Biol. 2014 Nov;247(11):1067-82. doi: 10.1007/s00232-014-9715-3. Epub 2014 Aug 9. Review.

8.

The Concise Guide to PHARMACOLOGY 2013/14: enzymes.

Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators.

Br J Pharmacol. 2013 Dec;170(8):1797-867. doi: 10.1111/bph.12451.

9.

Cytochromes p450: roles in diseases.

Pikuleva IA, Waterman MR.

J Biol Chem. 2013 Jun 14;288(24):17091-8. doi: 10.1074/jbc.R112.431916. Epub 2013 Apr 30. Review.

10.

Cholesterol oxidation in the retina: implications of 7KCh formation in chronic inflammation and age-related macular degeneration.

Rodríguez IR, Larrayoz IM.

J Lipid Res. 2010 Oct;51(10):2847-62. doi: 10.1194/jlr.R004820. Epub 2010 Jun 21. Review.

11.

Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain?

Ogundare M, Theofilopoulos S, Lockhart A, Hall LJ, Arenas E, Sjövall J, Brenton AG, Wang Y, Griffiths WJ.

J Biol Chem. 2010 Feb 12;285(7):4666-79. doi: 10.1074/jbc.M109.086678. Epub 2009 Dec 7.

12.

CYP7B1: one cytochrome P450, two human genetic diseases, and multiple physiological functions.

Stiles AR, McDonald JG, Bauman DR, Russell DW.

J Biol Chem. 2009 Oct 16;284(42):28485-9. doi: 10.1074/jbc.R109.042168. Epub 2009 Aug 16. Review.

13.

Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brain.

Russell DW, Halford RW, Ramirez DM, Shah R, Kotti T.

Annu Rev Biochem. 2009;78:1017-40. doi: 10.1146/annurev.biochem.78.072407.103859. Review.

14.

Activation of PXR induces hypercholesterolemia in wild-type and accelerates atherosclerosis in apoE deficient mice.

Zhou C, King N, Chen KY, Breslow JL.

J Lipid Res. 2009 Oct;50(10):2004-13. doi: 10.1194/jlr.M800608-JLR200. Epub 2009 May 12.

15.

Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation.

Kotti T, Head DD, McKenna CE, Russell DW.

Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11394-9. doi: 10.1073/pnas.0805556105. Epub 2008 Aug 6.

16.

Metabolism of a novel side chain modified Delta8(14)-15-ketosterol, a potential cholesterol lowering drug: 28-hydroxylation by CYP27A1.

Pettersson H, Norlin M, Andersson U, Pikuleva I, Björkhem I, Misharin AY, Wikvall K.

Biochim Biophys Acta. 2008 Aug;1781(8):383-90. doi: 10.1016/j.bbalip.2008.05.009. Epub 2008 Jun 11.

17.

Neuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brain.

Ramirez DM, Andersson S, Russell DW.

J Comp Neurol. 2008 Apr 10;507(5):1676-93. doi: 10.1002/cne.21605.

18.
19.

Brain cholesterol turnover required for geranylgeraniol production and learning in mice.

Kotti TJ, Ramirez DM, Pfeiffer BE, Huber KM, Russell DW.

Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3869-74. Epub 2006 Feb 27.

20.

Regulation of bile acid biosynthesis by hepatocyte nuclear factor 4alpha.

Inoue Y, Yu AM, Yim SH, Ma X, Krausz KW, Inoue J, Xiang CC, Brownstein MJ, Eggertsen G, Björkhem I, Gonzalez FJ.

J Lipid Res. 2006 Jan;47(1):215-27. Epub 2005 Nov 1.

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