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Silibinin Treatment Inhibits the Growth of Hedgehog Inhibitor-Resistant Basal Cell Carcinoma Cells via Targeting EGFR-MAPK-Akt and Hedgehog Signaling.

Dheeraj A, Rigby CM, O'Bryant CL, Agarwal C, Singh RP, Deep G, Agarwal R.

Photochem Photobiol. 2017 Jul;93(4):999-1007. doi: 10.1111/php.12727. Epub 2017 Mar 6.


Blockade of the Hedgehog pathway downregulates estrogen receptor alpha signaling in breast cancer cells.

Diao Y, Azatyan A, Rahman MF, Zhao C, Zhu J, Dahlman-Wright K, Zaphiropoulos PG.

Oncotarget. 2016 Nov 1;7(44):71580-71593. doi: 10.18632/oncotarget.12259.


Gene Expression and Proteome Analysis as Sources of Biomarkers in Basal Cell Carcinoma.

Lupu M, Caruntu C, Ghita MA, Voiculescu V, Voiculescu S, Rosca AE, Caruntu A, Moraru L, Popa IM, Calenic B, Greabu M, Costea DE.

Dis Markers. 2016;2016:9831237. doi: 10.1155/2016/9831237. Epub 2016 Aug 8. Review.


Disruption of Vitamin D and Calcium Signaling in Keratinocytes Predisposes to Skin Cancer.

Bikle DD, Jiang Y, Nguyen T, Oda Y, Tu CL.

Front Physiol. 2016 Jul 12;7:296. doi: 10.3389/fphys.2016.00296. eCollection 2016. Review.


Basal Cell Carcinoma in Gorlin's Patients: a Matter of Fibroblasts-Led Protumoral Microenvironment?

Gache Y, Brellier F, Rouanet S, Al-Qaraghuli S, Goncalves-Maia M, Burty-Valin E, Barnay S, Scarzello S, Ruat M, Sevenet N, Avril MF, Magnaldo T.

PLoS One. 2015 Dec 22;10(12):e0145369. doi: 10.1371/journal.pone.0145369. eCollection 2015.


Aberrant GLI1 Activation in DNA Damage Response, Carcinogenesis and Chemoresistance.

Palle K, Mani C, Tripathi K, Athar M.

Cancers (Basel). 2015 Nov 27;7(4):2330-51. doi: 10.3390/cancers7040894. Review.


Active IKKβ promotes the stability of GLI1 oncogene in diffuse large B-cell lymphoma.

Agarwal NK, Kim CH, Kunkalla K, Konno H, Tjendra Y, Kwon D, Blonska M, Kozloski GA, Moy VT, Verdun RE, Barber GN, Lossos IS, Vega F.

Blood. 2016 Feb 4;127(5):605-15. doi: 10.1182/blood-2015-07-658781. Epub 2015 Nov 24.


Role of GLI1 and NDRG1 in Increased Resistance to Apoptosis Induction.

Wu F, Rom WN, Koshiji M, Mo Y, Hosomi Y, Tchou-Wong KM.

J Environ Pathol Toxicol Oncol. 2015;34(3):213-25.


Basal cell carcinoma: pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management.

Marzuka AG, Book SE.

Yale J Biol Med. 2015 Jun 1;88(2):167-79. eCollection 2015 Jun. Review.


LncRNA BCAR4 wires up signaling transduction in breast cancer.

Xing Z, Park PK, Lin C, Yang L.

RNA Biol. 2015;12(7):681-9. doi: 10.1080/15476286.2015.1053687.


Basal cell carcinoma preferentially arises from stem cells within hair follicle and mechanosensory niches.

Peterson SC, Eberl M, Vagnozzi AN, Belkadi A, Veniaminova NA, Verhaegen ME, Bichakjian CK, Ward NL, Dlugosz AA, Wong SY.

Cell Stem Cell. 2015 Apr 2;16(4):400-12. doi: 10.1016/j.stem.2015.02.006.


Molecular docking approaches in identification of High affinity inhibitors of Human SMO receptor.

Akare UR, Bandaru S, Shaheen U, Singh PK, Tiwari G, Singare P, Nayarisseri A, Banerjee T.

Bioinformation. 2014 Dec 31;10(12):737-42. doi: 10.6026/97320630010737. eCollection 2014.


CK2α, over-expressed in human malignant pleural mesothelioma, regulates the Hedgehog signaling pathway in mesothelioma cells.

Zhang S, Yang YL, Wang Y, You B, Dai Y, Chan G, Hsieh D, Kim IJ, Fang LT, Au A, Stoppler HJ, Xu Z, Jablons DM, You L.

J Exp Clin Cancer Res. 2014 Nov 25;33:93. doi: 10.1186/s13046-014-0093-6.


Genetic activation of Hedgehog signaling unbalances the rate of neural stem cell renewal by increasing symmetric divisions.

Ferent J, Cochard L, Faure H, Taddei M, Hahn H, Ruat M, Traiffort E.

Stem Cell Reports. 2014 Aug 12;3(2):312-23. doi: 10.1016/j.stemcr.2014.05.016. Epub 2014 Jun 19.


Advanced treatment for basal cell carcinomas.

Atwood SX, Whitson RJ, Oro AE.

Cold Spring Harb Perspect Med. 2014 Jul 1;4(7):a013581. doi: 10.1101/cshperspect.a013581. Review.


Identification of novel non-coding RNA-based negative feedback regulating the expression of the oncogenic transcription factor GLI1.

Villegas VE, Rahman MF, Fernandez-Barrena MG, Diao Y, Liapi E, Sonkoly E, Ståhle M, Pivarcsi A, Annaratone L, Sapino A, Ramírez Clavijo S, Bürglin TR, Shimokawa T, Ramachandran S, Kapranov P, Fernandez-Zapico ME, Zaphiropoulos PG.

Mol Oncol. 2014 Jul;8(5):912-26. doi: 10.1016/j.molonc.2014.03.009. Epub 2014 Mar 22.


The sonic hedgehog-induced type 3 deiodinase facilitates tumorigenesis of basal cell carcinoma by reducing Gli2 inactivation.

Luongo C, Ambrosio R, Salzano S, Dlugosz AA, Missero C, Dentice M.

Endocrinology. 2014 Jun;155(6):2077-88. doi: 10.1210/en.2013-2108. Epub 2014 Apr 2.


Dynamic Hedgehog signalling pathway activity in germline stem cells.

Sahin Z, Szczepny A, McLaughlin EA, Meistrich ML, Zhou W, Ustunel I, Loveland KL.

Andrology. 2014 Mar;2(2):267-74. doi: 10.1111/j.2047-2927.2014.00187.x.


Role of CRD-BP in the growth of human basal cell carcinoma cells.

Noubissi FK, Kim T, Kawahara TN, Aughenbaugh WD, Berg E, Longley BJ, Athar M, Spiegelman VS.

J Invest Dermatol. 2014 Jun;134(6):1718-1724. doi: 10.1038/jid.2014.17. Epub 2014 Jan 27.


Multiple trichoepitheliomas: A rare occurrence.

Karikal A, Shetty P, Karikal A, Shetty SR.

South Asian J Cancer. 2013 Apr;2(2):54. doi: 10.4103/2278-330X.110479.

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