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Items: 19


Hematopoietic Stem Cell Mobilization Is Necessary but Not Sufficient for Tolerance in Islet Transplantation.

Stocks BT, Thomas AB, Elizer SK, Zhu Y, Marshall AF, Wilson CS, Moore DJ.

Diabetes. 2017 Jan;66(1):127-133. doi: 10.2337/db16-0444. Epub 2016 Oct 26.


Treg cells in pancreatic lymph nodes: the possible role in diabetogenesis and β cell regeneration in a T1D model.

Nti BK, Markman JL, Bertera S, Styche AJ, Lakomy RJ, Subbotin VM, Trucco M, Zorina TD.

Cell Mol Immunol. 2012 Nov;9(6):455-63. doi: 10.1038/cmi.2012.36. Epub 2012 Oct 8.


FTY720 markedly increases alloengraftment but does not eliminate host anti-donor T cells that cause graft rejection on its withdrawal.

Taylor PA, Kelly RM, Bade ND, Smith MJ, Stefanski HE, Blazar BR.

Biol Blood Marrow Transplant. 2012 Sep;18(9):1341-52. doi: 10.1016/j.bbmt.2012.06.007. Epub 2012 Jun 19.


Mesenchymal stem cells facilitate mixed hematopoietic chimerism induction and prevent onset of diabetes in nonobese diabetic mice.

Asari S, Itakura S, Rawson J, Ito T, Todorov I, Nair I, Shintaku J, Liu CP, Kandeel F, Mullen YS.

Pancreas. 2011 Aug;40(6):846-54. doi: 10.1097/MPA.0b013e318215cdce.


Induction of mixed chimerism with MHC-mismatched but not matched bone marrow transplants results in thymic deletion of host-type autoreactive T-cells in NOD mice.

Racine J, Wang M, Zhang C, Lin CL, Liu H, Todorov I, Atkinson M, Zeng D.

Diabetes. 2011 Feb;60(2):555-64. doi: 10.2337/db10-0827. Erratum in: Diabetes. 2011 Mar;60(3):1052.


Stem cell-based strategies for the treatment of type 1 diabetes mellitus.

Wen Y, Chen B, Ildstad ST.

Expert Opin Biol Ther. 2011 Jan;11(1):41-53. doi: 10.1517/14712598.2011.540235. Epub 2010 Nov 29. Review.


Cardioprotection with postconditioning: loss of efficacy in murine models of type-2 and type-1 diabetes.

Przyklenk K, Maynard M, Greiner DL, Whittaker P.

Antioxid Redox Signal. 2011 Mar 1;14(5):781-90. doi: 10.1089/ars.2010.3343. Epub 2010 Oct 6.


Induction of chimerism permits low-dose islet grafts in the liver or pancreas to reverse refractory autoimmune diabetes.

Zhang C, Wang M, Racine JJ, Liu H, Lin CL, Nair I, Lau J, Cao YA, Todorov I, Atkinson M, Zeng D.

Diabetes. 2010 Sep;59(9):2228-36. doi: 10.2337/db10-0450. Epub 2010 Jun 8.


Distinct requirements for achievement of allotolerance versus reversal of autoimmunity via nonmyeloablative mixed chimerism induction in NOD mice.

Nikolic B, Onoe T, Takeuchi Y, Khalpey Z, Primo V, Leykin I, Smith RN, Sykes M.

Transplantation. 2010 Jan 15;89(1):23-32. doi: 10.1097/TP.0b013e3181c4692e.


CTLA-4 on alloreactive CD4 T cells interacts with recipient CD80/86 to promote tolerance.

Kurtz J, Raval F, Vallot C, Der J, Sykes M.

Blood. 2009 Apr 9;113(15):3475-84. doi: 10.1182/blood-2008-01-133736. Epub 2009 Jan 29.


Idd loci synergize to prolong islet allograft survival induced by costimulation blockade in NOD mice.

Mangada J, Pearson T, Brehm MA, Wicker LS, Peterson LB, Shultz LD, Serreze DV, Rossini AA, Greiner DL.

Diabetes. 2009 Jan;58(1):165-73. doi: 10.2337/db08-0275. Epub 2008 Nov 4.


Murine mobilized peripheral blood stem cells have a lower capacity than bone marrow to induce mixed chimerism and tolerance.

Koporc Z, Pilat N, Nierlich P, Blaha P, Bigenzahn S, Pree I, Selzer E, Sykes M, Muehlbacher F, Wekerle T.

Am J Transplant. 2008 Oct;8(10):2025-36. doi: 10.1111/j.1600-6143.2008.02371.x.


Manipulating the immune system for anti-tumor responses and transplant tolerance via mixed hematopoietic chimerism.

Gibbons C, Sykes M.

Immunol Rev. 2008 Jun;223:334-60. doi: 10.1111/j.1600-065X.2008.00636.x. Review.


Elimination of insulitis and augmentation of islet beta cell regeneration via induction of chimerism in overtly diabetic NOD mice.

Zhang C, Todorov I, Lin CL, Atkinson M, Kandeel F, Forman S, Zeng D.

Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2337-42. Epub 2007 Jan 31.


Humoral immunity is the dominant barrier for allogeneic bone marrow engraftment in sensitized recipients.

Xu H, Chilton PM, Tanner MK, Huang Y, Schanie CL, Dy-Liacco M, Yan J, Ildstad ST.

Blood. 2006 Nov 15;108(10):3611-9. Epub 2006 Aug 3.


Prevention of type 1 diabetes by gene therapy.

Tian C, Bagley J, Cretin N, Seth N, Wucherpfennig KW, Iacomini J.

J Clin Invest. 2004 Oct;114(7):969-78.


Skin allograft maintenance in a new synchimeric model system of tolerance.

Iwakoshi NN, Markees TG, Turgeon N, Thornley T, Cuthbert A, Leif J, Phillips NE, Mordes JP, Greiner DL, Rossini AA.

J Immunol. 2001 Dec 1;167(11):6623-30.


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