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Items: 1 to 20 of 116


A Review of Notch Processing With New Insights Into Ligand-Independent Notch Signaling in T-Cells.

Steinbuck MP, Winandy S.

Front Immunol. 2018 Jun 1;9:1230. doi: 10.3389/fimmu.2018.01230. eCollection 2018. Review.


Novel TCR-Mediated Mechanisms of Notch Activation and Signaling.

Steinbuck MP, Arakcheeva K, Winandy S.

J Immunol. 2018 Feb 1;200(3):997-1007. doi: 10.4049/jimmunol.1700070. Epub 2017 Dec 29.


Application of Electrochemical Devices to Characterize the Dynamic Actions of Helicases on DNA.

Kahanda D, DuPrez KT, Hilario E, McWilliams MA, Wohlgamuth CH, Fan L, Slinker JD.

Anal Chem. 2018 Feb 6;90(3):2178-2185. doi: 10.1021/acs.analchem.7b04515. Epub 2018 Jan 17.


Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT.

Court H, Ahearn IM, Amoyel M, Bach EA, Philips MR.

J Cell Biol. 2017 Dec 4;216(12):4165-4182. doi: 10.1083/jcb.201701053. Epub 2017 Oct 19.


Mediator 1 contributes to enamel mineralization as a coactivator for Notch1 signaling and stimulates transcription of the alkaline phosphatase gene.

Yoshizaki K, Hu L, Nguyen T, Sakai K, Ishikawa M, Takahashi I, Fukumoto S, DenBesten PK, Bikle DD, Oda Y, Yamada Y.

J Biol Chem. 2017 Aug 18;292(33):13531-13540. doi: 10.1074/jbc.M117.780866. Epub 2017 Jul 3.


A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self-renewal.

Chen KY, Srinivasan T, Tung KL, Belmonte JM, Wang L, Murthy PKL, Choi J, Rakhilin N, King S, Varanko AK, Witherspoon M, Nishimura N, Glazier JA, Lipkin SM, Bu P, Shen X.

Mol Syst Biol. 2017 Apr 28;13(4):927. doi: 10.15252/msb.20167324.


The Varied Roles of Notch in Cancer.

Aster JC, Pear WS, Blacklow SC.

Annu Rev Pathol. 2017 Jan 24;12:245-275. doi: 10.1146/annurev-pathol-052016-100127. Epub 2016 Dec 5. Review.


Notch1 controls development of the extravillous trophoblast lineage in the human placenta.

Haider S, Meinhardt G, Saleh L, Fiala C, Pollheimer J, Knöfler M.

Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):E7710-E7719. Epub 2016 Nov 14.


The Mechanism of Regulated Release of Lasso/Teneurin-2.

Vysokov NV, Silva JP, Lelianova VG, Ho C, Djamgoz MB, Tonevitsky AG, Ushkaryov YA.

Front Mol Neurosci. 2016 Jul 22;9:59. doi: 10.3389/fnmol.2016.00059. eCollection 2016.


Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies.

Weisshuhn PC, Sheppard D, Taylor P, Whiteman P, Lea SM, Handford PA, Redfield C.

Structure. 2016 Apr 5;24(4):555-566. doi: 10.1016/j.str.2016.02.010. Epub 2016 Mar 17.


Glycosylated Notch and Cancer.

Pakkiriswami S, Couto A, Nagarajan U, Georgiou M.

Front Oncol. 2016 Feb 18;6:37. doi: 10.3389/fonc.2016.00037. eCollection 2016. Review.


Evidence That the "Lid" Domain of Nicastrin Is Not Essential for Regulating γ-Secretase Activity.

Zhang X, Sullivan E, Scimeca M, Wu X, Li YM, Sisodia SS.

J Biol Chem. 2016 Mar 25;291(13):6748-53. doi: 10.1074/jbc.C115.701649. Epub 2016 Feb 17.


The clerodane diterpene casearin J induces apoptosis of T-ALL cells through SERCA inhibition, oxidative stress, and interference with Notch1 signaling.

De Ford C, Heidersdorf B, Haun F, Murillo R, Friedrich T, Borner C, Merfort I.

Cell Death Dis. 2016 Jan 28;7:e2070. doi: 10.1038/cddis.2015.413.


Notch-Mediated Cell Adhesion.

Murata A, Hayashi S.

Biology (Basel). 2016 Jan 16;5(1). pii: E5. doi: 10.3390/biology5010005. Review.


Control of lysosomal biogenesis and Notch-dependent tissue patterning by components of the TFEB-V-ATPase axis in Drosophila melanogaster.

Tognon E, Kobia F, Busi I, Fumagalli A, De Masi F, Vaccari T.

Autophagy. 2016;12(3):499-514. doi: 10.1080/15548627.2015.1134080. Epub 2016 Jan 4.


The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling.

Drusenheimer N, Migdal B, Jäckel S, Tveriakhina L, Scheider K, Schulz K, Gröper J, Köhrer K, Klein T.

PLoS Genet. 2015 Dec 31;11(12):e1005749. doi: 10.1371/journal.pgen.1005749. eCollection 2015 Dec.


Ligand-Independent Mechanisms of Notch Activity.

Palmer WH, Deng WM.

Trends Cell Biol. 2015 Nov;25(11):697-707. doi: 10.1016/j.tcb.2015.07.010. Epub 2015 Oct 1. Review.


TQ inhibits hepatocellular carcinoma growth in vitro and in vivo via repression of Notch signaling.

Ke X, Zhao Y, Lu X, Wang Z, Liu Y, Ren M, Lu G, Zhang D, Sun Z, Xu Z, Song JH, Cheng Y, Meltzer SJ, He S.

Oncotarget. 2015 Oct 20;6(32):32610-21. doi: 10.18632/oncotarget.5362.


Mutational analysis of the Notch2 negative regulatory region identifies key structural elements for mechanical stability.

Stephenson NL, Avis JM.

FEBS Open Bio. 2015 Jul 30;5:625-33. doi: 10.1016/j.fob.2015.07.006. eCollection 2015.


Cryosectioning Method for Microdissection of Murine Colonic Mucosa.

Farkas AE, Gerner-Smidt C, Lili L, Nusrat A, Capaldo CT.

J Vis Exp. 2015 Jul 12;(101):e53112. doi: 10.3791/53112.

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