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Items: 1 to 20 of 199


Tandem trimer pyrrole-imidazole polyamide probes targeting 18 base pairs in human telomere sequences.

Kawamoto Y, Sasaki A, Hashiya K, Ide S, Bando T, Maeshima K, Sugiyama H.

Chem Sci. 2015 Apr 1;6(4):2307-2312. doi: 10.1039/c4sc03755c. Epub 2015 Jan 20.


Reconstitution of human shelterin complexes reveals unexpected stoichiometry and dual pathways to enhance telomerase processivity.

Lim CJ, Zaug AJ, Kim HJ, Cech TR.

Nat Commun. 2017 Oct 20;8(1):1075. doi: 10.1038/s41467-017-01313-w.


Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity.

Chan FL, Vinod B, Novy K, Schittenhelm RB, Huang C, Udugama M, Nunez-Iglesias J, Lin JI, Hii L, Chan J, Pickett HA, Daly RJ, Wong LH.

Nucleic Acids Res. 2017 Dec 1;45(21):12340-12353. doi: 10.1093/nar/gkx904.


Basic domain of telomere guardian TRF2 reduces D-loop unwinding whereas Rap1 restores it.

Necasová I, Janoušková E, Klumpler T, Hofr C.

Nucleic Acids Res. 2017 Dec 1;45(21):12170-12180. doi: 10.1093/nar/gkx812.


Systematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cells.

Kim H, Li F, He Q, Deng T, Xu J, Jin F, Coarfa C, Putluri N, Liu D, Songyang Z.

Cell Discov. 2017 Sep 26;3:17034. doi: 10.1038/celldisc.2017.34. eCollection 2017.


The mre11 A470 alleles influence the hereditability and the segregation of telosomes in Saccharomyces cerevisiae.

Baek IJ, Moss DS, Lustig AJ.

PLoS One. 2017 Sep 8;12(9):e0183549. doi: 10.1371/journal.pone.0183549. eCollection 2017.


BRD4 inhibitors block telomere elongation.

Wang S, Pike AM, Lee SS, Strong MA, Connelly CJ, Greider CW.

Nucleic Acids Res. 2017 Aug 21;45(14):8403-8410. doi: 10.1093/nar/gkx561.


Regulation of Telomere Homeostasis during Epstein-Barr virus Infection and Immortalization.

Kamranvar SA, Masucci MG.

Viruses. 2017 Aug 9;9(8). pii: E217. doi: 10.3390/v9080217. Review.


Telomere Biology-Insights into an Intriguing Phenomenon.

Venkatesan S, Khaw AK, Hande MP.

Cells. 2017 Jun 19;6(2). pii: E15. doi: 10.3390/cells6020015. Review.


TZAP-ing telomeres down to size.

Garcia-Exposito L, O'Sullivan RJ.

EMBO Rep. 2017 Jun;18(6):861-863. doi: 10.15252/embr.201744354. Epub 2017 May 12.


Integrated analysis of promoter methylation and expression of telomere related genes in breast cancer.

Heng J, Zhang F, Guo X, Tang L, Peng L, Luo X, Xu X, Wang S, Dai L, Wang J.

Oncotarget. 2017 Apr 11;8(15):25442-25454. doi: 10.18632/oncotarget.16036.


Repetitive DNA loci and their modulation by the non-canonical nucleic acid structures R-loops and G-quadruplexes.

Hall AC, Ostrowski LA, Pietrobon V, Mekhail K.

Nucleus. 2017 Mar 4;8(2):162-181. doi: 10.1080/19491034.2017.1292193. Review.


Fundamental mechanisms of telomerase action in yeasts and mammals: understanding telomeres and telomerase in cancer cells.

Armstrong CA, Tomita K.

Open Biol. 2017 Mar;7(3). pii: 160338. doi: 10.1098/rsob.160338. Review.


Control of Cellular Aging, Tissue Function, and Cancer by p53 Downstream of Telomeres.

Roake CM, Artandi SE.

Cold Spring Harb Perspect Med. 2017 May 1;7(5). pii: a026088. doi: 10.1101/cshperspect.a026088. Review.


Preparation of 6/8/11-Amino/Chloro-Oxoisoaporphine and Group-10 Metal Complexes and Evaluation of Their in Vitro and in Vivo Antitumor Activity.

Qin QP, Qin JL, Meng T, Yang GA, Wei ZZ, Liu YC, Liang H, Chen ZF.

Sci Rep. 2016 Nov 29;6:37644. doi: 10.1038/srep37644.


Endogenous Telomerase Reverse Transcriptase N-Terminal Tagging Affects Human Telomerase Function at Telomeres In Vivo.

Chiba K, Vogan JM, Wu RA, Gill MS, Zhang X, Collins K, Hockemeyer D.

Mol Cell Biol. 2017 Jan 19;37(3). pii: e00541-16. doi: 10.1128/MCB.00541-16. Print 2017 Feb 1.


Means to the ends: The role of telomeres and telomere processing machinery in metastasis.

Robinson NJ, Schiemann WP.

Biochim Biophys Acta. 2016 Dec;1866(2):320-329. doi: 10.1016/j.bbcan.2016.10.005. Epub 2016 Oct 18. Review.


Dynamic peptides of human TPP1 fulfill diverse functions in telomere maintenance.

Rajavel M, Orban T, Xu M, Hernandez-Sanchez W, de la Fuente M, Palczewski K, Taylor DJ.

Nucleic Acids Res. 2016 Dec 1;44(21):10467-10479. Epub 2016 Sep 20.


Telomerase Regulation from Beginning to the End.

MacNeil DE, Bensoussan HJ, Autexier C.

Genes (Basel). 2016 Sep 14;7(9). pii: E64. doi: 10.3390/genes7090064. Review.


Dynamic interactions of Arabidopsis TEN1: stabilizing telomeres in response to heat stress.

Lee JR, Xie X, Yang K, Zhang J, Lee SY, Shippen DE.

Plant Cell. 2016 Sep 8. pii: tpc.00408.2016. [Epub ahead of print]

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