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Items: 1 to 20 of 52


Chronically Increased Amino Acids Improve Insulin Secretion, Pancreatic Vascularity, and Islet Size in Growth-Restricted Fetal Sheep.

Brown LD, Davis M, Wai S, Wesolowski SR, Hay WW Jr, Limesand SW, Rozance PJ.

Endocrinology. 2016 Oct;157(10):3788-3799. Epub 2016 Aug 8.


Connective tissue growth factor is critical for proper β-cell function and pregnancy-induced β-cell hyperplasia in adult mice.

Pasek RC, Dunn JC, Elsakr JM, Aramandla M, Matta AR, Gannon M.

Am J Physiol Endocrinol Metab. 2016 Sep 1;311(3):E564-74. doi: 10.1152/ajpendo.00194.2016. Epub 2016 Jul 26.


Early Pregnancy Maternal Hepatocyte Growth Factor and Risk of Gestational Diabetes.

Dishi M, Hevner K, Qiu C, Fida NG, Abetew DF, Williams MA, Enquobahrie DA.

Br J Med Med Res. 2015;9(1). pii: BJMMR.18632. Epub 2015 Jun 11.


PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2.

Lakshmipathi J, Alvarez-Perez JC, Rosselot C, Casinelli GP, Stamateris RE, Rausell-Palamos F, O'Donnell CP, Vasavada RC, Scott DK, Alonso LC, Garcia-Ocaña A.

Diabetes. 2016 May;65(5):1283-96. doi: 10.2337/db15-1398. Epub 2016 Feb 11.


Pancreatic islet hepatocyte growth factor and vascular endothelial growth factor A signaling in growth restricted fetuses.

Rozance PJ, Hay WW Jr.

Mol Cell Endocrinol. 2016 Nov 5;435:78-84. doi: 10.1016/j.mce.2016.01.025. Epub 2016 Jan 26.


Human umbilical cord matrix-derived stem cells exert trophic effects on β-cell survival in diabetic rats and isolated islets.

Zhou Y, Hu Q, Chen F, Zhang J, Guo J, Wang H, Gu J, Ma L, Ho G.

Dis Model Mech. 2015 Dec;8(12):1625-33. doi: 10.1242/dmm.021857. Epub 2015 Sep 22.


Hepatic Insulin Resistance Following Chronic Activation of the CREB Coactivator CRTC2.

Hogan MF, Ravnskjaer K, Matsumura S, Huising MO, Hull RL, Kahn SE, Montminy M.

J Biol Chem. 2015 Oct 23;290(43):25997-6006. doi: 10.1074/jbc.M115.679266. Epub 2015 Sep 4.


Transgenic expression of the human growth hormone minigene promotes pancreatic β-cell proliferation.

Baan M, Kibbe CR, Bushkofsky JR, Harris TW, Sherman DS, Davis DB.

Am J Physiol Regul Integr Comp Physiol. 2015 Oct;309(7):R788-94. doi: 10.1152/ajpregu.00244.2015. Epub 2015 Jul 22.


Partial-Hepatectomized (70%) Model Shows a Correlation between Hepatocyte Growth Factor Levels and Beta-Cell Mass.

Araújo TG, Oliveira AG, Saad MJ.

Front Endocrinol (Lausanne). 2015 Feb 16;6:20. doi: 10.3389/fendo.2015.00020. eCollection 2015. No abstract available.


Hepatocyte growth factor ameliorates hyperglycemia and corrects β-cell mass in IRS2-deficient mice.

Alvarez-Perez JC, Rosa TC, Casinelli GP, Valle SR, Lakshmipathi J, Rosselot C, Rausell-Palamos F, Vasavada RC, García-Ocaña A.

Mol Endocrinol. 2014 Dec;28(12):2038-48. doi: 10.1210/me.2014-1207.


Placental insufficiency decreases pancreatic vascularity and disrupts hepatocyte growth factor signaling in the pancreatic islet endothelial cell in fetal sheep.

Rozance PJ, Anderson M, Martinez M, Fahy A, Macko AR, Kailey J, Seedorf GJ, Abman SH, Hay WW Jr, Limesand SW.

Diabetes. 2015 Feb;64(2):555-64. doi: 10.2337/db14-0462. Epub 2014 Sep 23.


Pancreatic β-cell proliferation in obesity.

Linnemann AK, Baan M, Davis DB.

Adv Nutr. 2014 May 14;5(3):278-88. doi: 10.3945/an.113.005488. Print 2014 May. Review.


Adult-onset deletion of Pten increases islet mass and beta cell proliferation in mice.

Yang KT, Bayan JA, Zeng N, Aggarwal R, He L, Peng Z, Kassa A, Kim M, Luo Z, Shi Z, Medina V, Boddupally K, Stiles BL.

Diabetologia. 2014 Feb;57(2):352-61. doi: 10.1007/s00125-013-3085-8. Epub 2013 Oct 26.


Hepatocyte growth factor/c-Met signaling is required for β-cell regeneration.

Alvarez-Perez JC, Ernst S, Demirci C, Casinelli GP, Mellado-Gil JM, Rausell-Palamos F, Vasavada RC, Garcia-Ocaña A.

Diabetes. 2014 Jan;63(1):216-23. doi: 10.2337/db13-0333. Epub 2013 Oct 2.


PTEN controls β-cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a.

Zeng N, Yang KT, Bayan JA, He L, Aggarwal R, Stiles JW, Hou X, Medina V, Abad D, Palian BM, Al-Abdullah I, Kandeel F, Johnson DL, Stiles BL.

Aging Cell. 2013 Dec;12(6):1000-11. doi: 10.1111/acel.12132. Epub 2013 Aug 6.


β-cell preservation and regeneration for diabetes treatment: where are we now?

Karadimos MJ, Kapoor A, El Khattabi I, Sharma A.

Diabetes Manag (Lond). 2012 May 1;2(3):213-222.


Differential regulation of embryonic and adult β cell replication.

Gunasekaran U, Hudgens CW, Wright BT, Maulis MF, Gannon M.

Cell Cycle. 2012 Jul 1;11(13):2431-42. doi: 10.4161/cc.20545. Epub 2012 Jul 1. Review.


Enhanced expression of VEGF-A in β cells increases endothelial cell number but impairs islet morphogenesis and β cell proliferation.

Cai Q, Brissova M, Reinert RB, Pan FC, Brahmachary P, Jeansson M, Shostak A, Radhika A, Poffenberger G, Quaggin SE, Jerome WG, Dumont DJ, Powers AC.

Dev Biol. 2012 Jul 1;367(1):40-54. doi: 10.1016/j.ydbio.2012.04.022. Epub 2012 Apr 24.


Loss of HGF/c-Met signaling in pancreatic β-cells leads to incomplete maternal β-cell adaptation and gestational diabetes mellitus.

Demirci C, Ernst S, Alvarez-Perez JC, Rosa T, Valle S, Shridhar V, Casinelli GP, Alonso LC, Vasavada RC, García-Ocana A.

Diabetes. 2012 May;61(5):1143-52. doi: 10.2337/db11-1154. Epub 2012 Mar 16.


Endothelial progenitor cell cotransplantation enhances islet engraftment by rapid revascularization.

Kang S, Park HS, Jo A, Hong SH, Lee HN, Lee YY, Park JS, Jung HS, Chung SS, Park KS.

Diabetes. 2012 Apr;61(4):866-76. doi: 10.2337/db10-1492. Epub 2012 Feb 23.

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