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Items: 18


An update on the role of intestinal cytochrome P450 enzymes in drug disposition.

Xie F, Ding X, Zhang QY.

Acta Pharm Sin B. 2016 Sep;6(5):374-383. Epub 2016 Aug 4. Review.


Assessment of a candidate marker constituent predictive of a dietary substance-drug interaction: case study with grapefruit juice and CYP3A4 drug substrates.

Ainslie GR, Wolf KK, Li Y, Connolly EA, Scarlett YV, Hull JH, Paine MF.

J Pharmacol Exp Ther. 2014 Dec;351(3):576-84. doi: 10.1124/jpet.114.216838. Epub 2014 Sep 24.


A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care.

Kast RE, Boockvar JA, Brüning A, Cappello F, Chang WW, Cvek B, Dou QP, Duenas-Gonzalez A, Efferth T, Focosi D, Ghaffari SH, Karpel-Massler G, Ketola K, Khoshnevisan A, Keizman D, Magné N, Marosi C, McDonald K, Muñoz M, Paranjpe A, Pourgholami MH, Sardi I, Sella A, Srivenugopal KS, Tuccori M, Wang W, Wirtz CR, Halatsch ME.

Oncotarget. 2013 Apr;4(4):502-30. Review.


Clinical therapeutics in pregnancy.

Feghali MN, Mattison DR.

J Biomed Biotechnol. 2011;2011:783528. doi: 10.1155/2011/783528. Epub 2011 Jul 6.


Improvement of colchicine oral bioavailability by incorporating eugenol in the nanoemulsion as an oil excipient and enhancer.

Shen Q, Wang Y, Zhang Y.

Int J Nanomedicine. 2011;6:1237-43. doi: 10.2147/IJN.S20903. Epub 2011 Jun 20.


The effect of grapefruit juice on drug disposition.

Hanley MJ, Cancalon P, Widmer WW, Greenblatt DJ.

Expert Opin Drug Metab Toxicol. 2011 Mar;7(3):267-86. doi: 10.1517/17425255.2011.553189. Epub 2011 Jan 22. Review.


Fruit juice inhibition of uptake transport: a new type of food-drug interaction.

Bailey DG.

Br J Clin Pharmacol. 2010 Nov;70(5):645-55. doi: 10.1111/j.1365-2125.2010.03722.x. Review.


Marginal increase of sunitinib exposure by grapefruit juice.

van Erp NP, Baker SD, Zandvliet AS, Ploeger BA, den Hollander M, Chen Z, den Hartigh J, König-Quartel JM, Guchelaar HJ, Gelderblom H.

Cancer Chemother Pharmacol. 2011 Mar;67(3):695-703. doi: 10.1007/s00280-010-1367-0. Epub 2010 May 29.


Effect of HEPES buffer on the uptake and transport of P-glycoprotein substrates and large neutral amino acids.

Luo S, Pal D, Shah SJ, Kwatra D, Paturi KD, Mitra AK.

Mol Pharm. 2010 Apr 5;7(2):412-20. doi: 10.1021/mp900193e.


Clinical outcomes and management of mechanism-based inhibition of cytochrome P450 3A4.

Zhou S, Chan E, Li X, Huang M.

Ther Clin Risk Manag. 2005 Mar;1(1):3-13.


Effects of clarithromycin and grapefruit juice on the pharmacokinetics of glibenclamide.

Lilja JJ, Niemi M, Fredrikson H, Neuvonen PJ.

Br J Clin Pharmacol. 2007 Jun;63(6):732-40. Epub 2007 Jan 12.


Effects of grapefruit juice on the pharmacokinetics of acebutolol.

Lilja JJ, Raaska K, Neuvonen PJ.

Br J Clin Pharmacol. 2005 Dec;60(6):659-63.


Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux.

Honda Y, Ushigome F, Koyabu N, Morimoto S, Shoyama Y, Uchiumi T, Kuwano M, Ohtani H, Sawada Y.

Br J Pharmacol. 2004 Dec;143(7):856-64. Epub 2004 Oct 25.


Enhanced saquinavir exposure in human immunodeficiency virus type 1-infected patients with diarrhea and/or wasting syndrome.

Trout H, Mentré F, Panhard X, Kodjo A, Escaut L, Pernet P, Gobert JG, Vittecoq D, Knellwolf AL, Caulin C, Bergmann JF.

Antimicrob Agents Chemother. 2004 Feb;48(2):538-45.


St Johns wort increases expression of P-glycoprotein: implications for drug interactions.

Hennessy M, Kelleher D, Spiers JP, Barry M, Kavanagh P, Back D, Mulcahy F, Feely J.

Br J Clin Pharmacol. 2002 Jan;53(1):75-82.


Effect of grapefruit juice on the disposition of omeprazole.

Mouly S, Paine MF.

Br J Clin Pharmacol. 2001 Aug;52(2):216-7. No abstract available.

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