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Items: 1 to 20 of 135

1.

Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent.

Gomes-Silva D, Mukherjee M, Srinivasan M, Krenciute G, Dakhova O, Zheng Y, Cabral JMS, Rooney CM, Orange JS, Brenner MK, Mamonkin M.

Cell Rep. 2017 Oct 3;21(1):17-26. doi: 10.1016/j.celrep.2017.09.015.

2.

Role of Herpes Simplex Virus 1 γ34.5 in the Regulation of IRF3 Signaling.

Manivanh R, Mehrbach J, Knipe DM, Leib DA.

J Virol. 2017 Nov 14;91(23). pii: e01156-17. doi: 10.1128/JVI.01156-17. Print 2017 Dec 1.

PMID:
28904192
3.

Unlocking the NF-κB Conundrum: Embracing Complexity to Achieve Specificity.

Begalli F, Bennett J, Capece D, Verzella D, D'Andrea D, Tornatore L, Franzoso G.

Biomedicines. 2017 Aug 22;5(3). pii: E50. doi: 10.3390/biomedicines5030050. Review.

4.

DNA damage-induced nuclear factor-kappa B activation and its roles in cancer progression.

Wang W, Mani AM, Wu ZH.

J Cancer Metastasis Treat. 2017;3:45-59. doi: 10.20517/2394-4722.2017.03. Epub 2017 Mar 27.

5.

The Emerging Roles of STING in Bacterial Infections.

Marinho FV, Benmerzoug S, Oliveira SC, Ryffel B, Quesniaux VFJ.

Trends Microbiol. 2017 Nov;25(11):906-918. doi: 10.1016/j.tim.2017.05.008. Epub 2017 Jun 15. Review.

PMID:
28625530
6.

The PYRIN domain-only protein POP2 inhibits inflammasome priming and activation.

Ratsimandresy RA, Chu LH, Khare S, de Almeida L, Gangopadhyay A, Indramohan M, Misharin AV, Greaves DR, Perlman H, Dorfleutner A, Stehlik C.

Nat Commun. 2017 Jun 5;8:15556. doi: 10.1038/ncomms15556.

7.

Molecular characterization, expression of chicken TBK1 gene and its effect on IRF3 signaling pathway.

Wang Y, Yin Y, Lan X, Ye F, Tian K, Zhao X, Yin H, Li D, Xu H, Liu Y, Zhu Q.

PLoS One. 2017 May 11;12(5):e0177608. doi: 10.1371/journal.pone.0177608. eCollection 2017.

8.

Encephalomyocarditis virus 3C protease attenuates type I interferon production through disrupting the TANK-TBK1-IKKε-IRF3 complex.

Huang L, Xiong T, Yu H, Zhang Q, Zhang K, Li C, Hu L, Zhang Y, Zhang L, Liu Q, Wang S, He X, Bu Z, Cai X, Cui S, Li J, Weng C.

Biochem J. 2017 Jun 9;474(12):2051-2065. doi: 10.1042/BCJ20161037.

9.

Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma.

Eskiocak B, McMillan EA, Mendiratta S, Kollipara RK, Zhang H, Humphries CG, Wang C, Garcia-Rodriguez J, Ding M, Zaman A, Rosales TI, Eskiocak U, Smith MP, Sudderth J, Komurov K, Deberardinis RJ, Wellbrock C, Davies MA, Wargo JA, Yu Y, De Brabander JK, Williams NS, Chin L, Rizos H, Long GV, Kittler R, White MA.

Cancer Discov. 2017 Aug;7(8):832-851. doi: 10.1158/2159-8290.CD-16-0955. Epub 2017 Apr 28.

PMID:
28455392
10.

Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade.

Zhang Q, Meng F, Chen S, Plouffe SW, Wu S, Liu S, Li X, Zhou R, Wang J, Zhao B, Liu J, Qin J, Zou J, Feng XH, Guan KL, Xu P.

Nat Cell Biol. 2017 Apr;19(4):362-374. doi: 10.1038/ncb3496. Epub 2017 Mar 27.

11.

Microglia activation due to obesity programs metabolic failure leading to type two diabetes.

Maldonado-Ruiz R, Montalvo-Martínez L, Fuentes-Mera L, Camacho A.

Nutr Diabetes. 2017 Mar 20;7(3):e254. doi: 10.1038/nutd.2017.10. Review.

12.

Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon β.

Bakshi S, Taylor J, Strickson S, McCartney T, Cohen P.

Biochem J. 2017 Mar 15;474(7):1163-1174. doi: 10.1042/BCJ20160992.

13.

The ATP-Dependent RNA Helicase DDX3X Modulates Herpes Simplex Virus 1 Gene Expression.

Khadivjam B, Stegen C, Hogue-Racine MA, El Bilali N, Döhner K, Sodeik B, Lippé R.

J Virol. 2017 Mar 29;91(8). pii: e02411-16. doi: 10.1128/JVI.02411-16. Print 2017 Apr 15.

14.

OX40 Cooperates with ICOS To Amplify Follicular Th Cell Development and Germinal Center Reactions during Infection.

Tahiliani V, Hutchinson TE, Abboud G, Croft M, Salek-Ardakani S.

J Immunol. 2017 Jan 1;198(1):218-228. Epub 2016 Nov 28.

PMID:
27895177
15.

Tank-Binding Kinase 1 (TBK1) Gene and Open-Angle Glaucomas (An American Ophthalmological Society Thesis).

Fingert JH, Robin AL, Scheetz TE, Kwon YH, Liebmann JM, Ritch R, Alward WL.

Trans Am Ophthalmol Soc. 2016 Aug;114:T6.

16.

Functional motifs responsible for human metapneumovirus M2-2-mediated innate immune evasion.

Chen Y, Deng X, Deng J, Zhou J, Ren Y, Liu S, Prusak DJ, Wood TG, Bao X.

Virology. 2016 Dec;499:361-368. doi: 10.1016/j.virol.2016.09.026. Epub 2016 Oct 13.

PMID:
27743962
17.

Inhibitory effects of an aqueous extract from Cortex Phellodendri on the growth and replication of broad-spectrum of viruses in vitro and in vivo.

Kim JH, Weeratunga P, Kim MS, Nikapitiya C, Lee BH, Uddin MB, Kim TH, Yoon JE, Park C, Ma JY, Kim H, Lee JS.

BMC Complement Altern Med. 2016 Aug 2;16:265. doi: 10.1186/s12906-016-1206-x.

18.

Recruitment of TBK1 to cytosol-invading Salmonella induces WIPI2-dependent antibacterial autophagy.

Thurston TL, Boyle KB, Allen M, Ravenhill BJ, Karpiyevich M, Bloor S, Kaul A, Noad J, Foeglein A, Matthews SA, Komander D, Bycroft M, Randow F.

EMBO J. 2016 Aug 15;35(16):1779-92. doi: 10.15252/embj.201694491. Epub 2016 Jul 1.

19.

Angiogenin ameliorates corneal opacity and neovascularization via regulating immune response in corneal fibroblasts.

Lee SH, Kim KW, Joo K, Kim JC.

BMC Ophthalmol. 2016 May 17;16:57. doi: 10.1186/s12886-016-0235-z.

20.

Human TBK1: A Gatekeeper of Neuroinflammation.

Ahmad L, Zhang SY, Casanova JL, Sancho-Shimizu V.

Trends Mol Med. 2016 Jun;22(6):511-27. doi: 10.1016/j.molmed.2016.04.006. Review.

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