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Antiviral activity of N-(4-hydroxyphenyl) retinamide (4-HPR) against Zika virus.

Pitts JD, Li PC, de Wispelaere M, Yang PL.

Antiviral Res. 2017 Nov;147:124-130. doi: 10.1016/j.antiviral.2017.10.014. Epub 2017 Oct 16.


Clinical development of fenretinide as an antineoplastic drug: Pharmacology perspectives.

Cooper JP, Reynolds CP, Cho H, Kang MH.

Exp Biol Med (Maywood). 2017 Jun;242(11):1178-1184. doi: 10.1177/1535370217706952. Epub 2017 Apr 21. Review.


Phase I Study of Fenretinide Delivered Intravenously in Patients with Relapsed or Refractory Hematologic Malignancies: A California Cancer Consortium Trial.

Mohrbacher AM, Yang AS, Groshen S, Kummar S, Gutierrez ME, Kang MH, Tsao-Wei D, Reynolds CP, Newman EM, Maurer BJ.

Clin Cancer Res. 2017 Aug 15;23(16):4550-4555. doi: 10.1158/1078-0432.CCR-17-0234. Epub 2017 Apr 18.


Retinoic acid directs breast cancer cell state changes through regulation of TET2-PKCζ pathway.

Wu MJ, Kim MR, Chen YS, Yang JY, Chang CJ.

Oncogene. 2017 Jun 1;36(22):3193-3206. doi: 10.1038/onc.2016.467. Epub 2017 Feb 20.


Retinoids and rexinoids in cancer prevention: from laboratory to clinic.

Uray IP, Dmitrovsky E, Brown PH.

Semin Oncol. 2016 Feb;43(1):49-64. doi: 10.1053/j.seminoncol.2015.09.002. Epub 2015 Sep 25. Review.


Retinoids induce cellular senescence in breast cancer cells by RAR-β dependent and independent pathways: Potential clinical implications (Review).

Shilkaitis A, Green A, Christov K.

Int J Oncol. 2015 Jul;47(1):35-42. doi: 10.3892/ijo.2015.3013. Epub 2015 May 18. Review.


Medical prevention of breast cancer.

Stubert J, Dieterich M, Gerber B.

Breast Care (Basel). 2014 Dec;9(6):391-6. doi: 10.1159/000369573. Review.


The bioactive lipid 4-hydroxyphenyl retinamide inhibits flavivirus replication.

Carocci M, Hinshaw SM, Rodgers MA, Villareal VA, Burri DJ, Pilankatta R, Maharaj NP, Gack MU, Stavale EJ, Warfield KL, Yang PL.

Antimicrob Agents Chemother. 2015 Jan;59(1):85-95. doi: 10.1128/AAC.04177-14. Epub 2014 Oct 13.


Anti-tumor activity of fenretinide complexed with human serum albumin in lung cancer xenograft mouse model.

Durante S, Orienti I, Teti G, Salvatore V, Focaroli S, Tesei A, Pignatta S, Falconi M.

Oncotarget. 2014 Jul 15;5(13):4811-20.


Advances in Preventive Therapy for Estrogen-Receptor-Negative Breast Cancer.

Litzenburger BC, Brown PH.

Curr Breast Cancer Rep. 2014;6:96-109. Review.


Ovarian and breast cancer spheres are similar in transcriptomic features and sensitive to fenretinide.

Wang H, Zhang Y, Du Y.

Biomed Res Int. 2013;2013:510905. doi: 10.1155/2013/510905. Epub 2013 Oct 8.


Targeted therapy for breast cancer prevention.

den Hollander P, Savage MI, Brown PH.

Front Oncol. 2013 Sep 23;3:250. doi: 10.3389/fonc.2013.00250. Review.


Fenretinide targets chronic myeloid leukemia stem/progenitor cells by regulation of redox signaling.

Du Y, Xia Y, Pan X, Chen Z, Wang A, Wang K, Li J, Zhang J.

Antioxid Redox Signal. 2014 Apr 20;20(12):1866-80. doi: 10.1089/ars.2012.4935. Epub 2013 Oct 24.


Flow Cytometric Analysis of 4-HPR-induced Apoptosis and Cell Cycle Arrest in Acute Myelocytic Leukemia Cell Line (NB-4).

Fard SS, Jeddi-Tehrani M, Akhondi MM, Hashemi M, Ardekani AM.

Avicenna J Med Biotechnol. 2010 Jan;2(1):53-61.


Cell survival and apoptosis signaling as therapeutic target for cancer: marine bioactive compounds.

Kalimuthu S, Se-Kwon K.

Int J Mol Sci. 2013 Jan 24;14(2):2334-54. doi: 10.3390/ijms14022334.


Molecular pathways: current role and future directions of the retinoic acid pathway in cancer prevention and treatment.

Connolly RM, Nguyen NK, Sukumar S.

Clin Cancer Res. 2013 Apr 1;19(7):1651-9. doi: 10.1158/1078-0432.CCR-12-3175. Epub 2013 Jan 15. Review.


Oral low dose and topical tamoxifen for breast cancer prevention: modern approaches for an old drug.

Lazzeroni M, Serrano D, Dunn BK, Heckman-Stoddard BM, Lee O, Khan S, Decensi A.

Breast Cancer Res. 2012 Oct 29;14(5):214. doi: 10.1186/bcr3233. Review.


Breast cancer chemoprevention: old and new approaches.

Cazzaniga M, Bonanni B.

J Biomed Biotechnol. 2012;2012:985620. doi: 10.1155/2012/985620. Epub 2012 Jul 17. Review.


Identification of mammalian target of rapamycin as a direct target of fenretinide both in vitro and in vivo.

Xie H, Zhu F, Huang Z, Lee MH, Kim DJ, Li X, Lim DY, Jung SK, Kang S, Li H, Reddy K, Wang L, Ma W, Lubet RA, Bode AM, Dong Z.

Carcinogenesis. 2012 Sep;33(9):1814-21. doi: 10.1093/carcin/bgs234. Epub 2012 Jul 12.

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