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Items: 1 to 20 of 69


Pulling MscL open via N-terminal and TM1 helices: A computational study towards engineering an MscL nanovalve.

Martinac AD, Bavi N, Bavi O, Martinac B.

PLoS One. 2017 Aug 31;12(8):e0183822. doi: 10.1371/journal.pone.0183822. eCollection 2017.


Ion-mediated conformational switches.

Knipe PC, Thompson S, Hamilton AD.

Chem Sci. 2015 Mar 1;6(3):1630-1639. doi: 10.1039/c4sc03525a. Epub 2014 Nov 21.


Synapses in the spotlight with synthetic optogenetics.

Berlin S, Isacoff EY.

EMBO Rep. 2017 May;18(5):677-692. doi: 10.15252/embr.201744010. Epub 2017 Apr 10. Review.


Activation of the mechanosensitive ion channel MscL by mechanical stimulation of supported Droplet-Hydrogel bilayers.

Rosholm KR, Baker MA, Ridone P, Nakayama Y, Rohde PR, Cuello LG, Lee LK, Martinac B.

Sci Rep. 2017 Mar 27;7:45180. doi: 10.1038/srep45180.


Voltage-Dependent Inactivation of MscS Occurs Independently of the Positively Charged Residues in the Transmembrane Domain.

Nomura T, Sokabe M, Yoshimura K.

Biomed Res Int. 2016;2016:2401657. doi: 10.1155/2016/2401657. Epub 2016 Dec 22.


Nanomechanical properties of MscL α helices: A steered molecular dynamics study.

Bavi N, Bavi O, Vossoughi M, Naghdabadi R, Hill AP, Martinac B, Jamali Y.

Channels (Austin). 2017 May 4;11(3):209-223. doi: 10.1080/19336950.2016.1249077. Epub 2016 Oct 18.


In situ, Reversible Gating of a Mechanosensitive Ion Channel through Protein-Lipid Interactions.

Dimitrova A, Walko M, Hashemi Shabestari M, Kumar P, Huber M, Kocer A.

Front Physiol. 2016 Sep 21;7:409. eCollection 2016.


From membrane tension to channel gating: A principal energy transfer mechanism for mechanosensitive channels.

Zhang XC, Liu Z, Li J.

Protein Sci. 2016 Nov;25(11):1954-1964. doi: 10.1002/pro.3017. Epub 2016 Aug 23. Review.


Can Nanofluidic Chemical Release Enable Fast, High Resolution Neurotransmitter-Based Neurostimulation?

Jones PD, Stelzle M.

Front Neurosci. 2016 Mar 31;10:138. doi: 10.3389/fnins.2016.00138. eCollection 2016. Erratum in: Front Neurosci. 2016;10:341.


Scanning MscL Channels with Targeted Post-Translational Modifications for Functional Alterations.

Iscla I, Wray R, Eaton C, Blount P.

PLoS One. 2015 Sep 14;10(9):e0137994. doi: 10.1371/journal.pone.0137994. eCollection 2015.


Mutations in a Conserved Domain of E. coli MscS to the Most Conserved Superfamily Residue Leads to Kinetic Changes.

Malcolm HR, Blount P.

PLoS One. 2015 Sep 4;10(9):e0136756. doi: 10.1371/journal.pone.0136756. eCollection 2015.


Molecular dynamics study on protein-water interplay in the mechanogating of the bacterial mechanosensitive channel MscL.

Sawada Y, Sokabe M.

Eur Biophys J. 2015 Oct;44(7):531-43. doi: 10.1007/s00249-015-1065-2. Epub 2015 Aug 2.


Breaking the hydrophobicity of the MscL pore: insights into a charge-induced gating mechanism.

Chandramouli B, Di Maio D, Mancini G, Barone V, Brancato G.

PLoS One. 2015 Mar 31;10(3):e0120196. doi: 10.1371/journal.pone.0120196. eCollection 2015.


Activation of a bacterial mechanosensitive channel in mammalian cells by cytoskeletal stress.

Heureaux J, Chen D, Murray VL, Deng CX, Liu AP.

Cell Mol Bioeng. 2014 Sep;7(3):307-319.


The mechanosensitive channel of small conductance (MscS) functions as a Jack-in-the box.

Malcolm HR, Blount P, Maurer JA.

Biochim Biophys Acta. 2015 Jan;1848(1 Pt A):159-66. doi: 10.1016/j.bbamem.2014.10.022. Epub 2014 Oct 23.


Global structural changes of an ion channel during its gating are followed by ion mobility mass spectrometry.

Konijnenberg A, Yilmaz D, Ingólfsson HI, Dimitrova A, Marrink SJ, Li Z, Vénien-Bryan C, Sobott F, Koçer A.

Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17170-5. doi: 10.1073/pnas.1413118111. Epub 2014 Nov 17.


Hydrophobic gating in ion channels.

Aryal P, Sansom MS, Tucker SJ.

J Mol Biol. 2015 Jan 16;427(1):121-30. doi: 10.1016/j.jmb.2014.07.030. Epub 2014 Aug 12. Review.


The activation mode of the mechanosensitive ion channel, MscL, by lysophosphatidylcholine differs from tension-induced gating.

Mukherjee N, Jose MD, Birkner JP, Walko M, Ingólfsson HI, Dimitrova A, Arnarez C, Marrink SJ, Koçer A.

FASEB J. 2014 Oct;28(10):4292-302. doi: 10.1096/fj.14-251579. Epub 2014 Jun 23.


Improving the Design of a MscL-Based Triggered Nanovalve.

Iscla I, Eaton C, Parker J, Wray R, Kovács Z, Blount P.

Biosensors (Basel). 2013;3(1):171-84. doi: 10.3390/bios3010171.

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