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Items: 1 to 20 of 43


A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex.

Teimer R, Kosinski J, von Appen A, Beck M, Hurt E.

Nat Commun. 2017 Oct 24;8(1):1107. doi: 10.1038/s41467-017-01160-9.


Investigating molecular crowding within nuclear pores using polarization-PALM.

Fu G, Tu LC, Zilman A, Musser SM.

Elife. 2017 Sep 26;6. pii: e28716. doi: 10.7554/eLife.28716.


The nuclear pore complex core scaffold and permeability barrier: variations of a common theme.

Hayama R, Rout MP, Fernandez-Martinez J.

Curr Opin Cell Biol. 2017 Jun;46:110-118. doi: 10.1016/ Epub 2017 Jun 15. Review.


Expression of Leukemia-Associated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype.

Fahrenkrog B, Martinelli V, Nilles N, Fruhmann G, Chatel G, Juge S, Sauder U, Di Giacomo D, Mecucci C, Schwaller J.

PLoS One. 2016 Mar 31;11(3):e0152321. doi: 10.1371/journal.pone.0152321. eCollection 2016.


Interactome Mapping Reveals the Evolutionary History of the Nuclear Pore Complex.

Obado SO, Brillantes M, Uryu K, Zhang W, Ketaren NE, Chait BT, Field MC, Rout MP.

PLoS Biol. 2016 Feb 18;14(2):e1002365. doi: 10.1371/journal.pbio.1002365. eCollection 2016 Feb.


Uncleavable Nup98-Nup96 is functional in the fission yeast Schizosaccharomyces pombe.

Asakawa H, Mori C, Ohtsuki C, Iwamoto M, Hiraoka Y, Haraguchi T.

FEBS Open Bio. 2015 Jun 12;5:508-14. doi: 10.1016/j.fob.2015.06.004. eCollection 2015.


Intranuclear dynamics of the Nup107-160 complex.

Morchoisne-Bolhy S, Geoffroy MC, Bouhlel IB, Alves A, Audugé N, Baudin X, Van Bortle K, Powers MA, Doye V.

Mol Biol Cell. 2015 Jun 15;26(12):2343-56. doi: 10.1091/mbc.E15-02-0060. Epub 2015 Apr 22.


An ancient autoproteolytic domain found in GAIN, ZU5 and Nucleoporin98.

Liao Y, Pei J, Cheng H, Grishin NV.

J Mol Biol. 2014 Dec 12;426(24):3935-45. doi: 10.1016/j.jmb.2014.10.011. Epub 2014 Oct 20.


Exploring the role of conformational heterogeneity in cis-autoproteolytic activation of ThnT.

Buller AR, Freeman MF, Schildbach JF, Townsend CA.

Biochemistry. 2014 Jul 8;53(26):4273-81. doi: 10.1021/bi500385d. Epub 2014 Jun 26.


A conserved role for human Nup98 in altering chromatin structure and promoting epigenetic transcriptional memory.

Light WH, Freaney J, Sood V, Thompson A, D'Urso A, Horvath CM, Brickner JH.

PLoS Biol. 2013;11(3):e1001524. doi: 10.1371/journal.pbio.1001524. Epub 2013 Mar 26.


In vivo analysis of human nucleoporin repeat domain interactions.

Xu S, Powers MA.

Mol Biol Cell. 2013 Apr;24(8):1222-31. doi: 10.1091/mbc.E12-08-0585. Epub 2013 Feb 20.


Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes.

Singer S, Zhao R, Barsotti AM, Ouwehand A, Fazollahi M, Coutavas E, Breuhahn K, Neumann O, Longerich T, Pusterla T, Powers MA, Giles KM, Leedman PJ, Hess J, Grunwald D, Bussemaker HJ, Singer RH, Schirmacher P, Prives C.

Mol Cell. 2012 Dec 14;48(5):799-810. doi: 10.1016/j.molcel.2012.09.020. Epub 2012 Oct 24.


Autoproteolytic activation of ThnT results in structural reorganization necessary for substrate binding and catalysis.

Buller AR, Labonte JW, Freeman MF, Wright NT, Schildbach JF, Townsend CA.

J Mol Biol. 2012 Sep 28;422(4):508-18. doi: 10.1016/j.jmb.2012.06.012. Epub 2012 Jun 15.


Autolytic proteolysis within the function to find domain (FIIND) is required for NLRP1 inflammasome activity.

Finger JN, Lich JD, Dare LC, Cook MN, Brown KK, Duraiswami C, Bertin J, Gough PJ.

J Biol Chem. 2012 Jul 20;287(30):25030-7. doi: 10.1074/jbc.M112.378323. Epub 2012 Jun 4. Erratum in: J Biol Chem. 2012 Sep 7;287(37):31456. Bertin, John J [corrected to Bertin, John].


Molecular basis for the anchoring of proto-oncoprotein Nup98 to the cytoplasmic face of the nuclear pore complex.

Stuwe T, von Borzyskowski LS, Davenport AM, Hoelz A.

J Mol Biol. 2012 Jun 22;419(5):330-46. doi: 10.1016/j.jmb.2012.03.024. Epub 2012 Apr 2.


The yeast nuclear pore complex and transport through it.

Aitchison JD, Rout MP.

Genetics. 2012 Mar;190(3):855-83. doi: 10.1534/genetics.111.127803.


Insights into cis-autoproteolysis reveal a reactive state formed through conformational rearrangement.

Buller AR, Freeman MF, Wright NT, Schildbach JF, Townsend CA.

Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2308-13. doi: 10.1073/pnas.1113633109. Epub 2012 Jan 30.


P53-induced protein with a death domain (PIDD): master of puppets?

Bock FJ, Peintner L, Tanzer M, Manzl C, Villunger A.

Oncogene. 2012 Nov 8;31(45):4733-9. doi: 10.1038/onc.2011.639. Epub 2012 Jan 23. Review.


The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade.

Heinz LX, Rebsamen M, Rossi DC, Staehli F, Schroder K, Quadroni M, Gross O, Schneider P, Tschopp J.

Cell Death Differ. 2012 Apr;19(4):722-31. doi: 10.1038/cdd.2011.147. Epub 2011 Dec 9.

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