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Items: 1 to 20 of 97

1.

S-nitrosylation of UCHL1 induces its structural instability and promotes α-synuclein aggregation.

Kumar R, Jangir DK, Verma G, Shekhar S, Hanpude P, Kumar S, Kumari R, Singh N, Sarovar Bhavesh N, Ranjan Jana N, Kanti Maiti T.

Sci Rep. 2017 Mar 16;7:44558. doi: 10.1038/srep44558.

2.

Life and death in the trash heap: The ubiquitin proteasome pathway and UCHL1 in brain aging, neurodegenerative disease and cerebral Ischemia.

Graham SH, Liu H.

Ageing Res Rev. 2017 Mar;34:30-38. doi: 10.1016/j.arr.2016.09.011. Epub 2016 Oct 1. Review.

PMID:
27702698
3.

Ubiquitin C-terminal hydrolase L1 (UCH-L1): structure, distribution and roles in brain function and dysfunction.

Bishop P, Rocca D, Henley JM.

Biochem J. 2016 Aug 15;473(16):2453-62. doi: 10.1042/BCJ20160082. Review.

4.

Absence of UCHL 1 function leads to selective motor neuropathy.

Genç B, Jara JH, Schultz MC, Manuel M, Stanford MJ, Gautam M, Klessner JL, Sekerkova G, Heller DB, Cox GA, Heckman CJ, DiDonato CJ, Özdinler PH.

Ann Clin Transl Neurol. 2016 Mar 7;3(5):331-45. doi: 10.1002/acn3.298. eCollection 2016 May.

5.

Emerging evidence of coding mutations in the ubiquitin-proteasome system associated with cerebellar ataxias.

Ronnebaum SM, Patterson C, Schisler JC.

Hum Genome Var. 2014 Oct 23;1:14018. doi: 10.1038/hgv.2014.18. eCollection 2014. Review.

6.

Neurodegeneration and Alzheimer's disease (AD). What Can Proteomics Tell Us About the Alzheimer's Brain?

Moya-Alvarado G, Gershoni-Emek N, Perlson E, Bronfman FC.

Mol Cell Proteomics. 2016 Feb;15(2):409-25. doi: 10.1074/mcp.R115.053330. Epub 2015 Dec 11. Review.

7.

Ubiquitin-Synaptobrevin Fusion Protein Causes Degeneration of Presynaptic Motor Terminals in Mice.

Liu Y, Li H, Sugiura Y, Han W, Gallardo G, Khvotchev M, Zhang Y, Kavalali ET, Südhof TC, Lin W.

J Neurosci. 2015 Aug 19;35(33):11514-31. doi: 10.1523/JNEUROSCI.5288-14.2015.

8.

The de novo synthesis of ubiquitin: identification of deubiquitinases acting on ubiquitin precursors.

Grou CP, Pinto MP, Mendes AV, Domingues P, Azevedo JE.

Sci Rep. 2015 Aug 3;5:12836. doi: 10.1038/srep12836.

9.

Protein monoubiquitylation: targets and diverse functions.

Nakagawa T, Nakayama K.

Genes Cells. 2015 Jul;20(7):543-62. doi: 10.1111/gtc.12250. Epub 2015 Jun 18. Review.

10.

Expression analysis of the long non-coding RNA antisense to Uchl1 (AS Uchl1) during dopaminergic cells' differentiation in vitro and in neurochemical models of Parkinson's disease.

Carrieri C, Forrest AR, Santoro C, Persichetti F, Carninci P, Zucchelli S, Gustincich S.

Front Cell Neurosci. 2015 Apr 1;9:114. doi: 10.3389/fncel.2015.00114. eCollection 2015.

11.

Corticospinal Motor Neurons Are Susceptible to Increased ER Stress and Display Profound Degeneration in the Absence of UCHL1 Function.

Jara JH, Genç B, Cox GA, Bohn MC, Roos RP, Macklis JD, Ulupınar E, Özdinler PH.

Cereb Cortex. 2015 Nov;25(11):4259-72. doi: 10.1093/cercor/bhu318. Epub 2015 Jan 16.

12.

Parkin-mediated K63-polyubiquitination targets ubiquitin C-terminal hydrolase L1 for degradation by the autophagy-lysosome system.

McKeon JE, Sha D, Li L, Chin LS.

Cell Mol Life Sci. 2015 May;72(9):1811-24. doi: 10.1007/s00018-014-1781-2. Epub 2014 Nov 18.

13.

An optimal ubiquitin-proteasome pathway in the nervous system: the role of deubiquitinating enzymes.

Ristic G, Tsou WL, Todi SV.

Front Mol Neurosci. 2014 Aug 19;7:72. doi: 10.3389/fnmol.2014.00072. eCollection 2014. Review.

14.

Screening of DUB activity and specificity by MALDI-TOF mass spectrometry.

Ritorto MS, Ewan R, Perez-Oliva AB, Knebel A, Buhrlage SJ, Wightman M, Kelly SM, Wood NT, Virdee S, Gray NS, Morrice NA, Alessi DR, Trost M.

Nat Commun. 2014 Aug 27;5:4763. doi: 10.1038/ncomms5763.

15.

Maternal effect genes: Findings and effects on mouse embryo development.

Kim KH, Lee KA.

Clin Exp Reprod Med. 2014 Jun;41(2):47-61. doi: 10.5653/cerm.2014.41.2.47. Epub 2014 Jun 30. Review.

16.

Loss of UCHL1 promotes age-related degenerative changes in the enteric nervous system.

Coulombe J, Gamage P, Gray MT, Zhang M, Tang MY, Woulfe J, Saffrey MJ, Gray DA.

Front Aging Neurosci. 2014 Jun 19;6:129. doi: 10.3389/fnagi.2014.00129. eCollection 2014.

17.

Cellular ubiquitin pool dynamics and homeostasis.

Park CW, Ryu KY.

BMB Rep. 2014 Sep;47(9):475-82. Review.

18.
19.

Identification of a gene set to evaluate the potential effects of loud sounds from seismic surveys on the ears of fishes: a study with Salmo salar.

Andrews CD, Payne JF, Rise ML.

J Fish Biol. 2014 Jun;84(6):1793-819. doi: 10.1111/jfb.12398. Epub 2014 May 9.

20.

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