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Items: 20


Somatic Cell Nuclear Transfer Followed by CRIPSR/Cas9 Microinjection Results in Highly Efficient Genome Editing in Cloned Pigs.

Sheets TP, Park CH, Park KE, Powell A, Donovan DM, Telugu BP.

Int J Mol Sci. 2016 Dec 3;17(12). pii: E2031.


The role of small adaptor proteins in the control of oncogenic signalingr driven by tyrosine kinases in human cancer.

Naudin C, Chevalier C, Roche S.

Oncotarget. 2016 Mar 8;7(10):11033-55. doi: 10.18632/oncotarget.6929. Review.


Identifying three-dimensional structures of autophosphorylation complexes in crystals of protein kinases.

Xu Q, Malecka KL, Fink L, Jordan EJ, Duffy E, Kolander S, Peterson JR, Dunbrack RL Jr.

Sci Signal. 2015 Dec 1;8(405):rs13. doi: 10.1126/scisignal.aaa6711.


Tissue-specific regulation and function of Grb10 during growth and neuronal commitment.

Plasschaert RN, Bartolomei MS.

Proc Natl Acad Sci U S A. 2015 Jun 2;112(22):6841-7. doi: 10.1073/pnas.1411254111. Epub 2014 Nov 3. Review.


Targeting receptor tyrosine kinases and their downstream signaling with cell-penetrating peptides in human pulmonary artery smooth muscle and endothelial cells.

Yu J, Rupasinghe C, Wilson JL, Taylor L, Rahimi N, Mierke D, Polgar P.

Chem Biol Drug Des. 2015 May;85(5):586-97. doi: 10.1111/cbdd.12446. Epub 2014 Nov 5.


Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulation.

Girnita L, Worrall C, Takahashi S, Seregard S, Girnita A.

Cell Mol Life Sci. 2014 Jul;71(13):2403-27. doi: 10.1007/s00018-013-1514-y. Epub 2013 Nov 26. Review.


Genomic organization and control of the grb7 gene family.

Lucas-Fernández E, García-Palmero I, Villalobo A.

Curr Genomics. 2008 Mar;9(1):60-8. doi: 10.2174/138920208783884847.


Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation.

Porter CJ, Matthews JM, Mackay JP, Pursglove SE, Schmidberger JW, Leedman PJ, Pero SC, Krag DN, Wilce MC, Wilce JA.

BMC Struct Biol. 2007 Sep 25;7:58.


Peripheral disruption of the Grb10 gene enhances insulin signaling and sensitivity in vivo.

Wang L, Balas B, Christ-Roberts CY, Kim RY, Ramos FJ, Kikani CK, Li C, Deng C, Reyna S, Musi N, Dong LQ, DeFronzo RA, Liu F.

Mol Cell Biol. 2007 Sep;27(18):6497-505. Epub 2007 Jul 9.


Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life.

Smith FM, Holt LJ, Garfield AS, Charalambous M, Koumanov F, Perry M, Bazzani R, Sheardown SA, Hegarty BD, Lyons RJ, Cooney GJ, Daly RJ, Ward A.

Mol Cell Biol. 2007 Aug;27(16):5871-86. Epub 2007 Jun 11.


TAT peptide-based micelle system for potential active targeting of anti-cancer agents to acidic solid tumors.

Sethuraman VA, Bae YH.

J Control Release. 2007 Apr 2;118(2):216-24. Epub 2006 Dec 13.


Backbone nuclear relaxation characteristics and calorimetric investigation of the human Grb7-SH2/erbB2 peptide complex.

Ivancic M, Spuches AM, Guth EC, Daugherty MA, Wilcox DE, Lyons BA.

Protein Sci. 2005 Jun;14(6):1556-69.


Grb10 and Grb14: enigmatic regulators of insulin action--and more?

Holt LJ, Siddle K.

Biochem J. 2005 Jun 1;388(Pt 2):393-406. Review.


Kinase activation through dimerization by human SH2-B.

Nishi M, Werner ED, Oh BC, Frantz JD, Dhe-Paganon S, Hansen L, Lee J, Shoelson SE.

Mol Cell Biol. 2005 Apr;25(7):2607-21.


Insulin inhibits platelet-derived growth factor-induced cell proliferation.

Cirri P, Taddei ML, Chiarugi P, Buricchi F, Caselli A, Paoli P, Giannoni E, Camici G, Manao G, Raugei G, Ramponi G.

Mol Biol Cell. 2005 Jan;16(1):73-83. Epub 2004 Nov 3.


Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism.

Charalambous M, Smith FM, Bennett WR, Crew TE, Mackenzie F, Ward A.

Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8292-7. Epub 2003 Jun 26.


The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor.

Vecchione A, Marchese A, Henry P, Rotin D, Morrione A.

Mol Cell Biol. 2003 May;23(9):3363-72.


The adapter protein ZIP binds Grb14 and regulates its inhibitory action on insulin signaling by recruiting protein kinase Czeta.

Cariou B, Perdereau D, Cailliau K, Browaeys-Poly E, Béréziat V, Vasseur-Cognet M, Girard J, Burnol AF.

Mol Cell Biol. 2002 Oct;22(20):6959-70.


Role for the adaptor protein Grb10 in the activation of Akt.

Jahn T, Seipel P, Urschel S, Peschel C, Duyster J.

Mol Cell Biol. 2002 Feb;22(4):979-91.


Imprinting of human GRB10 and its mutations in two patients with Russell-Silver syndrome.

Yoshihashi H, Maeyama K, Kosaki R, Ogata T, Tsukahara M, Goto Y, Hata J, Matsuo N, Smith RJ, Kosaki K.

Am J Hum Genet. 2000 Aug;67(2):476-82. Epub 2000 Jun 12.

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