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Thalidomide is Associated With Increased T Cell Activation and Inflammation in Antiretroviral-naive HIV-infected Individuals in a Randomised Clinical Trial of Efficacy and Safety.

Vergara TRC, Samer S, Santos-Oliveira JR, Giron LB, Arif MS, Silva-Freitas ML, Cherman LA, Treitsman MS, Chebabo A, Sucupira MCA, Da-Cruz AM, Diaz RS; SPARC Working Group.

EBioMedicine. 2017 Sep;23:59-67. doi: 10.1016/j.ebiom.2017.08.007. Epub 2017 Aug 12.


Biological determinants of radioresistance and their remediation in pancreatic cancer.

Seshacharyulu P, Baine MJ, Souchek JJ, Menning M, Kaur S, Yan Y, Ouellette MM, Jain M, Lin C, Batra SK.

Biochim Biophys Acta. 2017 Aug;1868(1):69-92. doi: 10.1016/j.bbcan.2017.02.003. Epub 2017 Feb 27. Review.


Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment.

Schenk RL, Tuzlak S, Carrington EM, Zhan Y, Heinzel S, Teh CE, Gray DH, Tai L, Lew AM, Villunger A, Strasser A, Herold MJ.

Cell Death Differ. 2017 Mar;24(3):534-545. doi: 10.1038/cdd.2016.156. Epub 2017 Jan 13.


The preclinical discovery and development of bortezomib for the treatment of mantle cell lymphoma.

Arkwright R, Pham TM, Zonder JA, Dou QP.

Expert Opin Drug Discov. 2017 Feb;12(2):225-235. doi: 10.1080/17460441.2017.1268596. Epub 2016 Dec 20. Review.


Intrinsic Resistance to 5-Fluorouracil in a Brain Metastatic Variant of Human Breast Cancer Cell Line, MDA-MB-231BR.

Sagara A, Igarashi K, Otsuka M, Karasawa T, Gotoh N, Narita M, Kuzumaki N, Narita M, Kato Y.

PLoS One. 2016 Oct 10;11(10):e0164250. doi: 10.1371/journal.pone.0164250. eCollection 2016.


NF-κB protects human neuroblastoma cells from nitric oxide-induced apoptosis through upregulating biglycan.

Wang L, Cheng BF, Yang HJ, Wang M, Feng ZW.

Am J Transl Res. 2015 Sep 15;7(9):1541-52. eCollection 2015.


Selective Nuclear Export Inhibitor KPT-330 Enhances the Antitumor Activity of Gemcitabine in Human Pancreatic Cancer.

Kazim S, Malafa MP, Coppola D, Husain K, Zibadi S, Kashyap T, Crochiere M, Landesman Y, Rashal T, Sullivan DM, Mahipal A.

Mol Cancer Ther. 2015 Jul;14(7):1570-81. doi: 10.1158/1535-7163.MCT-15-0104. Epub 2015 May 1.


Bee venom inhibits growth of human cervical tumors in mice.

Lee HL, Park SH, Kim TM, Jung YY, Park MH, Oh SH, Yun HS, Jun HO, Yoo HS, Han SB, Lee US, Yoon JH, Song MJ, Hong JT.

Oncotarget. 2015 Mar 30;6(9):7280-92.


Curcumin sensitizes human lung cancer cells to apoptosis and metastasis synergistically combined with carboplatin.

Kang JH, Kang HS, Kim IK, Lee HY, Ha JH, Yeo CD, Kang HH, Moon HS, Lee SH.

Exp Biol Med (Maywood). 2015 Nov;240(11):1416-25. doi: 10.1177/1535370215571881. Epub 2015 Feb 25.


Up-regulation of anti-apoptotic genes confers resistance to the novel anti-leukaemic compound PEP005 in primary AML cells.

Hampson P, Wang K, Ersvær E, McCormack E, Schüler J, Fiebig HH, Gjertsen BT, Bruserud Ø, Lord JM.

Oncoscience. 2014 Aug 6;1(8):529-39. eCollection 2014.


Myeloid-derived suppressor activity is mediated by monocytic lineages maintained by continuous inhibition of extrinsic and intrinsic death pathways.

Haverkamp JM, Smith AM, Weinlich R, Dillon CP, Qualls JE, Neale G, Koss B, Kim Y, Bronte V, Herold MJ, Green DR, Opferman JT, Murray PJ.

Immunity. 2014 Dec 18;41(6):947-59. doi: 10.1016/j.immuni.2014.10.020. Epub 2014 Dec 11.


Methanolic Fractions of Ornithogalum cuspidatum Induce Apoptosis in PC-3 Prostate Cancer Cell Line and WEHI-164 Fibrosarcoma Cancer Cell Line.

Asadi H, Orangi M, Shanehbandi D, Babaloo Z, Delazar A, Mohammadnejad L, Zare Shahneh F, Valiyari S, Baradaran B.

Adv Pharm Bull. 2014 Oct;4(Suppl 1):455-8. doi: 10.5681/apb.2014.067. Epub 2014 Aug 25.


N-acetyl-L-cysteine sensitizes pancreatic cancers to gemcitabine by targeting the NFκB pathway.

Qanungo S, Uys JD, Manevich Y, Distler AM, Shaner B, Hill EG, Mieyal JJ, Lemasters JJ, Townsend DM, Nieminen AL.

Biomed Pharmacother. 2014 Sep;68(7):855-64. doi: 10.1016/j.biopha.2014.08.007. Epub 2014 Aug 28.


Isocudraxanthone K induces growth inhibition and apoptosis in oral cancer cells via hypoxia inducible factor-1α.

Shin MR, Lee HJ, Kang SK, Auh QS, Lee YM, Kim YC, Kim EC.

Biomed Res Int. 2014;2014:934691. doi: 10.1155/2014/934691. Epub 2014 Jul 3.


Defective apoptosis in intestinal and mesenteric adipose tissue of Crohn's disease patients.

Dias CB, Milanski M, Portovedo M, Horita V, Ayrizono Mde L, Planell N, Coy CS, Velloso LA, Meirelles LR, Leal RF.

PLoS One. 2014 Jun 2;9(6):e98547. doi: 10.1371/journal.pone.0098547. eCollection 2014.


SN50 enhances the effects of LY294002 on cell death induction in gastric cancer cell line SGC7901.

Zhao K, Zhu BS, Gong W, Zhu ML, Gao ZT, Wu YY, Chen Q, Yang XD, Xing CG.

Arch Med Sci. 2013 Dec 30;9(6):990-8. doi: 10.5114/aoms.2013.39790. Epub 2013 Dec 26.


To NFκB or not to NFκB: The Dilemma on How to Inhibit a Cancer Cell Fate Regulator.

Sorriento D, Illario M, Finelli R, Iaccarino G.

Transl Med UniSa. 2012 Oct 11;4:73-85. Print 2012 Sep.


Targeting nuclear factor-kappa B to overcome resistance to chemotherapy.

Godwin P, Baird AM, Heavey S, Barr MP, O'Byrne KJ, Gately K.

Front Oncol. 2013 May 16;3:120. doi: 10.3389/fonc.2013.00120. eCollection 2013.


Saikosaponin-d Enhances the Anticancer Potency of TNF-α via Overcoming Its Undesirable Response of Activating NF-Kappa B Signalling in Cancer Cells.

Wong VK, Zhang MM, Zhou H, Lam KY, Chan PL, Law CK, Yue PY, Liu L.

Evid Based Complement Alternat Med. 2013;2013:745295. doi: 10.1155/2013/745295. Epub 2013 Mar 12.

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