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Clock Genes and Altered Sleep-Wake Rhythms: Their Role in the Development of Psychiatric Disorders.

Charrier A, Olliac B, Roubertoux P, Tordjman S.

Int J Mol Sci. 2017 Apr 29;18(5). pii: E938. doi: 10.3390/ijms18050938.


Circadian Rhythm Neuropeptides in Drosophila: Signals for Normal Circadian Function and Circadian Neurodegenerative Disease.

He Q, Wu B, Price JL, Zhao Z.

Int J Mol Sci. 2017 Apr 21;18(4). pii: E886. doi: 10.3390/ijms18040886. Review.


FAD Regulates CRYPTOCHROME Protein Stability and Circadian Clock in Mice.

Hirano A, Braas D, Fu YH, Ptáček LJ.

Cell Rep. 2017 Apr 11;19(2):255-266. doi: 10.1016/j.celrep.2017.03.041.


Mutation of the Human Circadian Clock Gene CRY1 in Familial Delayed Sleep Phase Disorder.

Patke A, Murphy PJ, Onat OE, Krieger AC, Özçelik T, Campbell SS, Young MW.

Cell. 2017 Apr 6;169(2):203-215.e13. doi: 10.1016/j.cell.2017.03.027.


Vertebrate Cryptochromes are Vestigial Flavoproteins.

Kutta RJ, Archipowa N, Johannissen LO, Jones AR, Scrutton NS.

Sci Rep. 2017 Mar 20;7:44906. doi: 10.1038/srep44906.


Interaction between circadian rhythms and stress.

Koch CE, Leinweber B, Drengberg BC, Blaum C, Oster H.

Neurobiol Stress. 2016 Sep 8;6:57-67. doi: 10.1016/j.ynstr.2016.09.001. eCollection 2017 Feb. Review.


Formation of a repressive complex in the mammalian circadian clock is mediated by the secondary pocket of CRY1.

Michael AK, Fribourgh JL, Chelliah Y, Sandate CR, Hura GL, Schneidman-Duhovny D, Tripathi SM, Takahashi JS, Partch CL.

Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1560-1565. doi: 10.1073/pnas.1615310114. Epub 2017 Jan 31.


Cryptochromes regulate IGF-1 production and signaling through control of JAK2-dependent STAT5B phosphorylation.

Chaudhari A, Gupta R, Patel S, Velingkaar N, Kondratov R.

Mol Biol Cell. 2017 Mar 15;28(6):834-842. doi: 10.1091/mbc.E16-08-0624. Epub 2017 Jan 18.


Animal Cryptochromes: Divergent Roles in Light Perception, Circadian Timekeeping and Beyond.

Michael AK, Fribourgh JL, Van Gelder RN, Partch CL.

Photochem Photobiol. 2017 Jan;93(1):128-140. doi: 10.1111/php.12677. Epub 2017 Jan 18. Review.


Single-Cell Transcriptional Analysis Reveals Novel Neuronal Phenotypes and Interaction Networks Involved in the Central Circadian Clock.

Park J, Zhu H, O'Sullivan S, Ogunnaike BA, Weaver DR, Schwaber JS, Vadigepalli R.

Front Neurosci. 2016 Oct 25;10:481. eCollection 2016.


Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease.

Matsunaga N, Ikeda E, Kakimoto K, Watanabe M, Shindo N, Tsuruta A, Ikeyama H, Hamamura K, Higashi K, Yamashita T, Kondo H, Yoshida Y, Matsuda M, Ogino T, Tokushige K, Itcho K, Furuichi Y, Nakao T, Yasuda K, Doi A, Amamoto T, Aramaki H, Tsuda M, Inoue K, Ojida A, Koyanagi S, Ohdo S.

EBioMedicine. 2016 Nov;13:262-273. doi: 10.1016/j.ebiom.2016.10.008. Epub 2016 Oct 6.


Bmal1 Is Required for Normal Reproductive Behaviors in Male Mice.

Schoeller EL, Clark DD, Dey S, Cao NV, Semaan SJ, Chao LW, Kauffman AS, Stowers L, Mellon PL.

Endocrinology. 2016 Dec;157(12):4914-4929. Epub 2016 Oct 5.


Chronotherapy: Intuitive, Sound, Founded…But Not Broadly Applied.

Selfridge JM, Gotoh T, Schiffhauer S, Liu J, Stauffer PE, Li A, Capelluto DG, Finkielstein CV.

Drugs. 2016 Oct;76(16):1507-1521.


Mammalian Period represses and de-represses transcription by displacing CLOCK-BMAL1 from promoters in a Cryptochrome-dependent manner.

Chiou YY, Yang Y, Rashid N, Ye R, Selby CP, Sancar A.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6072-E6079. Epub 2016 Sep 29.


A Cryptochrome 2 mutation yields advanced sleep phase in humans.

Hirano A, Shi G, Jones CR, Lipzen A, Pennacchio LA, Xu Y, Hallows WC, McMahon T, Yamazaki M, Ptáček LJ, Fu YH.

Elife. 2016 Aug 16;5. pii: e16695. doi: 10.7554/eLife.16695.


Pacemaker-neuron-dependent disturbance of the molecular clockwork by a Drosophila CLOCK mutant homologous to the mouse Clock mutation.

Lee E, Cho E, Kang DH, Jeong EH, Chen Z, Yoo SH, Kim EY.

Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):E4904-13. doi: 10.1073/pnas.1523494113. Epub 2016 Aug 3.


Muscle-specific loss of Bmal1 leads to disrupted tissue glucose metabolism and systemic glucose homeostasis.

Harfmann BD, Schroder EA, Kachman MT, Hodge BA, Zhang X, Esser KA.

Skelet Muscle. 2016 Mar 30;6:12. doi: 10.1186/s13395-016-0082-x. eCollection 2016.


A novel role of microRNA 17-5p in the modulation of circadian rhythm.

Gao Q, Zhou L, Yang SY, Cao JM.

Sci Rep. 2016 Jul 21;6:30070. doi: 10.1038/srep30070.


HnRNP Q Has a Suppressive Role in the Translation of Mouse Cryptochrome1.

Lim I, Jung Y, Kim DY, Kim KT.

PLoS One. 2016 Jul 8;11(7):e0159018. doi: 10.1371/journal.pone.0159018. eCollection 2016.

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