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Endothelium-dependent vasodilation effects of Panax notoginseng and its main components are mediated by nitric oxide and cyclooxygenase pathways.

Wang Y, Ren Y, Xing L, Dai X, Liu S, Yu B, Wang Y.

Exp Ther Med. 2016 Dec;12(6):3998-4006. doi: 10.3892/etm.2016.3890. Epub 2016 Nov 9.


Cyclic nucleotide signalling in kidney fibrosis.

Schinner E, Wetzl V, Schlossmann J.

Int J Mol Sci. 2015 Jan 22;16(2):2320-51. doi: 10.3390/ijms16022320. Review.


Soluble guanylate cyclase is required for systemic vasodilation but not positive inotropy induced by nitroxyl in the mouse.

Zhu G, Groneberg D, Sikka G, Hori D, Ranek MJ, Nakamura T, Takimoto E, Paolocci N, Berkowitz DE, Friebe A, Kass DA.

Hypertension. 2015 Feb;65(2):385-92. doi: 10.1161/HYPERTENSIONAHA.114.04285. Epub 2014 Dec 1.


The Concise Guide to PHARMACOLOGY 2013/14: enzymes.

Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators.

Br J Pharmacol. 2013 Dec;170(8):1797-867. doi: 10.1111/bph.12451.


The role of valvular endothelial cell paracrine signaling and matrix elasticity on valvular interstitial cell activation.

Gould ST, Matherly EE, Smith JN, Heistad DD, Anseth KS.

Biomaterials. 2014 Apr;35(11):3596-606. doi: 10.1016/j.biomaterials.2014.01.005. Epub 2014 Jan 24.


Nitric oxide directly promotes vascular endothelial insulin transport.

Wang H, Wang AX, Aylor K, Barrett EJ.

Diabetes. 2013 Dec;62(12):4030-42. doi: 10.2337/db13-0627. Epub 2013 Jul 17.


Lack of effect of ODQ does not exclude cGMP signalling via NO-sensitive guanylyl cyclase.

Lies B, Groneberg D, Gambaryan S, Friebe A.

Br J Pharmacol. 2013 Sep;170(2):317-27. doi: 10.1111/bph.12275.


Stimulators of soluble guanylyl cyclase: future clinical indications.

Nossaman BD, Kadowitz PJ.

Ochsner J. 2013 Spring;13(1):147-56.


A cyclic guanosine monophosphate-dependent pathway can regulate net hepatic glucose uptake in vivo.

An Z, Winnick JJ, Moore MC, Farmer B, Smith M, Irimia JM, Roach PJ, Cherrington AD.

Diabetes. 2012 Oct;61(10):2433-41. Epub 2012 Jun 11.


Stimulators and activators of soluble guanylate cyclase: review and potential therapeutic indications.

Nossaman B, Pankey E, Kadowitz P.

Crit Care Res Pract. 2012;2012:290805. doi: 10.1155/2012/290805. Epub 2012 Feb 28.


A soluble guanylate cyclase-dependent mechanism is involved in the regulation of net hepatic glucose uptake by nitric oxide in vivo.

An Z, Winnick JJ, Farmer B, Neal D, Lautz M, Irimia JM, Roach PJ, Cherrington AD.

Diabetes. 2010 Dec;59(12):2999-3007. doi: 10.2337/db10-0138. Epub 2010 Sep 7.


Nitrite as regulator of hypoxic signaling in mammalian physiology.

van Faassen EE, Bahrami S, Feelisch M, Hogg N, Kelm M, Kim-Shapiro DB, Kozlov AV, Li H, Lundberg JO, Mason R, Nohl H, Rassaf T, Samouilov A, Slama-Schwok A, Shiva S, Vanin AF, Weitzberg E, Zweier J, Gladwin MT.

Med Res Rev. 2009 Sep;29(5):683-741. doi: 10.1002/med.20151. Review.


Endogenous methyl palmitate modulates nicotinic receptor-mediated transmission in the superior cervical ganglion.

Lin HW, Liu CZ, Cao D, Chen PY, Chen MF, Lin SZ, Mozayan M, Chen AF, Premkumar LS, Torry DS, Lee TJ.

Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19526-31. doi: 10.1073/pnas.0810262105. Epub 2008 Dec 4. Erratum in: Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):4060.


Soluble guanylyl cyclase contributes to ventilator-induced lung injury in mice.

Schmidt EP, Damarla M, Rentsendorj O, Servinsky LE, Zhu B, Moldobaeva A, Gonzalez A, Hassoun PM, Pearse DB.

Am J Physiol Lung Cell Mol Physiol. 2008 Dec;295(6):L1056-65. doi: 10.1152/ajplung.90329.2008. Epub 2008 Oct 10.


cGMP-independent anti-tumour actions of the inhibitor of soluble guanylyl cyclase, ODQ, in prostate cancer cell lines.

Haramis G, Zhou Z, Pyriochou A, Koutsilieris M, Roussos C, Papapetropoulos A.

Br J Pharmacol. 2008 Nov;155(6):804-13. doi: 10.1038/bjp.2008.312. Epub 2008 Aug 11.


Heme proteins mediate the conversion of nitrite to nitric oxide in the vascular wall.

Alzawahra WF, Talukder MA, Liu X, Samouilov A, Zweier JL.

Am J Physiol Heart Circ Physiol. 2008 Aug;295(2):H499-508. doi: 10.1152/ajpheart.00374.2008. Epub 2008 Jun 6.


Endothelial nitric oxide attenuates Na+/Ca2+ exchanger-mediated vasoconstriction in rat aorta.

Zhao J, Majewski H.

Br J Pharmacol. 2008 Jul;154(5):982-90. doi: 10.1038/bjp.2008.178. Epub 2008 May 12.


Positive inotropic effects of carbon monoxide-releasing molecules (CO-RMs) in the isolated perfused rat heart.

Musameh MD, Fuller BJ, Mann BE, Green CJ, Motterlini R.

Br J Pharmacol. 2006 Dec;149(8):1104-12. Epub 2006 Oct 23.


NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential.

Evgenov OV, Pacher P, Schmidt PM, Haskó G, Schmidt HH, Stasch JP.

Nat Rev Drug Discov. 2006 Sep;5(9):755-68. Review.

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