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Carboxyl-terminal truncated HBx contributes to invasion and metastasis via deregulating metastasis suppressors in hepatocellular carcinoma.

Li W, Li M, Liao D, Lu X, Gu X, Zhang Q, Zhang Z, Li H.

Oncotarget. 2016 Aug 23;7(34):55110-55127. doi: 10.18632/oncotarget.10399.


Hepatocellular carcinoma and hepatitis B surface protein.

Li YW, Yang FC, Lu HQ, Zhang JS.

World J Gastroenterol. 2016 Feb 14;22(6):1943-52. doi: 10.3748/wjg.v22.i6.1943. Review.


Hepatitis B virus X protein induces EpCAM expression via active DNA demethylation directed by RelA in complex with EZH2 and TET2.

Fan H, Zhang H, Pascuzzi PE, Andrisani O.

Oncogene. 2016 Feb 11;35(6):715-26. doi: 10.1038/onc.2015.122. Epub 2015 Apr 20.


PLK1 and HOTAIR Accelerate Proteasomal Degradation of SUZ12 and ZNF198 during Hepatitis B Virus-Induced Liver Carcinogenesis.

Zhang H, Diab A, Fan H, Mani SK, Hullinger R, Merle P, Andrisani O.

Cancer Res. 2015 Jun 1;75(11):2363-74. doi: 10.1158/0008-5472.CAN-14-2928. Epub 2015 Apr 8.


Hepatitis B virus, HBx mutants and their role in hepatocellular carcinoma.

Ali A, Abdel-Hafiz H, Suhail M, Al-Mars A, Zakaria MK, Fatima K, Ahmad S, Azhar E, Chaudhary A, Qadri I.

World J Gastroenterol. 2014 Aug 14;20(30):10238-48. doi: 10.3748/wjg.v20.i30.10238. Review.


Clinical implications of hepatitis B virus mutations: recent advances.

Lazarevic I.

World J Gastroenterol. 2014 Jun 28;20(24):7653-64. doi: 10.3748/wjg.v20.i24.7653. Review.


Molecular targeted therapy for hepatocellular carcinoma: current and future.

Shin JW, Chung YH.

World J Gastroenterol. 2013 Oct 7;19(37):6144-55. doi: 10.3748/wjg.v19.i37.6144. Review.


Deregulation of epigenetic mechanisms by the hepatitis B virus X protein in hepatocarcinogenesis.

Andrisani OM.

Viruses. 2013 Mar 18;5(3):858-72. doi: 10.3390/v5030858. Review.


Modulation of apoptotic signaling by the hepatitis B virus X protein.

Rawat S, Clippinger AJ, Bouchard MJ.

Viruses. 2012 Nov 8;4(11):2945-72. doi: 10.3390/v4112945. Review.


Liver cell transformation in chronic HBV infection.

Benhenda S, Cougot D, Neuveut C, Buendia MA.

Viruses. 2009 Dec;1(3):630-46. doi: 10.3390/v1030630. Epub 2009 Oct 30.


Induction of cyclooxygenase-2 expression by hepatitis B virus depends on demethylation-associated recruitment of transcription factors to the promoter.

Yue X, Yang F, Yang Y, Mu Y, Sun W, Li W, Xu D, Wu J, Zhu Y.

Virol J. 2011 Mar 14;8:118. doi: 10.1186/1743-422X-8-118.


DNA replication licensing control and rereplication prevention.

Li C, Jin J.

Protein Cell. 2010 Mar;1(3):227-36. doi: 10.1007/s13238-010-0032-z. Epub 2010 Feb 23. Review.


Gene signatures in hepatocellular carcinoma (HCC).

Andrisani OM, Studach L, Merle P.

Semin Cancer Biol. 2011 Feb;21(1):4-9. doi: 10.1016/j.semcancer.2010.09.002. Epub 2010 Sep 17. Review.


Polo-like kinase 1 activated by the hepatitis B virus X protein attenuates both the DNA damage checkpoint and DNA repair resulting in partial polyploidy.

Studach L, Wang WH, Weber G, Tang J, Hullinger RL, Malbrue R, Liu X, Andrisani O.

J Biol Chem. 2010 Sep 24;285(39):30282-93. doi: 10.1074/jbc.M109.093963. Epub 2010 Jul 12.


Plk1-mediated phosphorylation of Topors regulates p53 stability.

Yang X, Li H, Zhou Z, Wang WH, Deng A, Andrisani O, Liu X.

J Biol Chem. 2009 Jul 10;284(28):18588-92. doi: 10.1074/jbc.C109.001560. Epub 2009 May 27.


Polo-like kinase 1 inhibition suppresses hepatitis B virus X protein-induced transformation in an in vitro model of liver cancer progression.

Studach LL, Rakotomalala L, Wang WH, Hullinger RL, Cairo S, Buendia MA, Andrisani OM.

Hepatology. 2009 Aug;50(2):414-23. doi: 10.1002/hep.22996.


Deregulated direct targets of the hepatitis B virus (HBV) protein, HBx, identified through chromatin immunoprecipitation and expression microarray profiling.

Sung WK, Lu Y, Lee CW, Zhang D, Ronaghi M, Lee CG.

J Biol Chem. 2009 Aug 14;284(33):21941-54. doi: 10.1074/jbc.M109.014563. Epub 2009 May 13.


Hepatitis B virus X protein modulates apoptosis in primary rat hepatocytes by regulating both NF-kappaB and the mitochondrial permeability transition pore.

Clippinger AJ, Gearhart TL, Bouchard MJ.

J Virol. 2009 May;83(10):4718-31. doi: 10.1128/JVI.02590-08. Epub 2009 Mar 11.


Hepatitis B virus X protein increases the Cdt1-to-geminin ratio inducing DNA re-replication and polyploidy.

Rakotomalala L, Studach L, Wang WH, Gregori G, Hullinger RL, Andrisani O.

J Biol Chem. 2008 Oct 17;283(42):28729-40. doi: 10.1074/jbc.M802751200. Epub 2008 Aug 8.

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