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Items: 1 to 20 of 118


Detecting RNA base methylations in single cells by in situ hybridization.

Ranasinghe RT, Challand MR, Ganzinger KA, Lewis BW, Softley C, Schmied WH, Horrocks MH, Shivji N, Chin JW, Spencer J, Klenerman D.

Nat Commun. 2018 Feb 13;9(1):655. doi: 10.1038/s41467-017-02714-7.


Single Nucleotide Polymorphism Genotyping in Single-Molecule Electronic Circuits.

He G, Li J, Qi C, Guo X.

Adv Sci (Weinh). 2017 Jul 26;4(11):1700158. doi: 10.1002/advs.201700158. eCollection 2017 Nov.


The use of nanocrystal quantum dot as fluorophore reporters in molecular beacon-based assays.

Adegoke O, Park EY.

Nano Converg. 2016;3(1):32. doi: 10.1186/s40580-016-0094-6. Epub 2016 Dec 1. Review.


Establishment of an accurate and fast detection method using molecular beacons in loop-mediated isothermal amplification assay.

Liu W, Huang S, Liu N, Dong D, Yang Z, Tang Y, Ma W, He X, Ao D, Xu Y, Zou D, Huang L.

Sci Rep. 2017 Jan 6;7:40125. doi: 10.1038/srep40125.


Nonequilibrium Hybridization Enables Discrimination of a Point Mutation within 5-40 °C.

Stancescu M, Fedotova TA, Hooyberghs J, Balaeff A, Kolpashchikov DM.

J Am Chem Soc. 2016 Oct 4. [Epub ahead of print]


Continuously tunable nucleic acid hybridization probes.

Wu LR, Wang JS, Fang JZ, Evans ER, Pinto A, Pekker I, Boykin R, Ngouenet C, Webster PJ, Beechem J, Zhang DY.

Nat Methods. 2015 Dec;12(12):1191-6. doi: 10.1038/nmeth.3626. Epub 2015 Oct 19.


In silico and in vitro evaluation of exonic and intronic off-target effects form a critical element of therapeutic ASO gapmer optimization.

Kamola PJ, Kitson JD, Turner G, Maratou K, Eriksson S, Panjwani A, Warnock LC, Douillard Guilloux GA, Moores K, Koppe EL, Wixted WE, Wilson PA, Gooderham NJ, Gant TW, Clark KL, Hughes SA, Edbrooke MR, Parry JD.

Nucleic Acids Res. 2015 Oct 15;43(18):8638-50. doi: 10.1093/nar/gkv857. Epub 2015 Sep 3.


Ag nanocluster-based label-free catalytic and molecular beacons for amplified biosensing.

Gong L, Kuai H, Ren S, Zhao XH, Huan SY, Zhang XB, Tan W.

Chem Commun (Camb). 2015 Aug 4;51(60):12095-8. doi: 10.1039/c5cc04442a.


Comparative Evaluation of Sloppy Molecular Beacon and Dual-Labeled Probe Melting Temperature Assays to Identify Mutations in Mycobacterium tuberculosis Resulting in Rifampin, Fluoroquinolone and Aminoglycoside Resistance.

Roh SS, Smith LE, Lee JS, Via LE, Barry CE 3rd, Alland D, Chakravorty S.

PLoS One. 2015 May 4;10(5):e0126257. doi: 10.1371/journal.pone.0126257. eCollection 2015.


Multiplexed programmable release of captured DNA.

Kennedy-Darling J, Holden MT, Shortreed MR, Smith LM.

Chembiochem. 2014 Nov 3;15(16):2353-6. doi: 10.1002/cbic.201402343. Epub 2014 Aug 26.


Kinetic hairpin oligonucleotide blockers for selective amplification of rare mutations.

Jia Y, Sanchez JA, Wangh LJ.

Sci Rep. 2014 Aug 1;4:5921. doi: 10.1038/srep05921.


Sensitive multiplex PCR assay to differentiate Lyme spirochetes and emerging pathogens Anaplasma phagocytophilum and Babesia microti.

Chan K, Marras SA, Parveen N.

BMC Microbiol. 2013 Dec 20;13:295. doi: 10.1186/1471-2180-13-295.


An elegant biosensor molecular beacon probe: challenges and recent solutions.

Kolpashchikov DM.

Scientifica (Cairo). 2012;2012:928783. doi: 10.6064/2012/928783. Epub 2012 Dec 13. Review.


Selective nucleic acid capture with shielded covalent probes.

Vieregg JR, Nelson HM, Stoltz BM, Pierce NA.

J Am Chem Soc. 2013 Jul 3;135(26):9691-9. doi: 10.1021/ja4009216. Epub 2013 Jun 18.


Monovalent streptavidin that senses oligonucleotides.

Taylor SK, Wang J, Kostic N, Stojanovic MN.

Angew Chem Int Ed Engl. 2013 May 17;52(21):5509-12. doi: 10.1002/anie.201209948. Epub 2013 Apr 19. No abstract available.


Reversible metal-dependent destabilization and stabilization of a stem-chelate-loop probe binding to an unmodified DNA target.

Morgan JR, Nguyen DV, Frohman AR, Rybka SR, Zebala JA.

Bioconjug Chem. 2012 Oct 17;23(10):2020-4. doi: 10.1021/bc3003293. Epub 2012 Sep 20.


Tiny molecular beacons: LNA/2'-O-methyl RNA chimeric probes for imaging dynamic mRNA processes in living cells.

Catrina IE, Marras SA, Bratu DP.

ACS Chem Biol. 2012 Sep 21;7(9):1586-95. Epub 2012 Jul 6.


Rapid hybridization of nucleic acids using isotachophoresis.

Bercovici M, Han CM, Liao JC, Santiago JG.

Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11127-32. doi: 10.1073/pnas.1205004109. Epub 2012 Jun 25.


Optimizing the specificity of nucleic acid hybridization.

Zhang DY, Chen SX, Yin P.

Nat Chem. 2012 Jan 22;4(3):208-14. doi: 10.1038/nchem.1246.

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