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Items: 1 to 20 of 142


SGK1 Inhibits Autophagy in Murine Muscle Tissue.

Zuleger T, Heinzelbecker J, Takacs Z, Hunter C, Voelkl J, Lang F, Proikas-Cezanne T.

Oxid Med Cell Longev. 2018 Apr 22;2018:4043726. doi: 10.1155/2018/4043726. eCollection 2018.


Orai3 calcium channel and resistance to chemotherapy in breast cancer cells: the p53 connection.

Hasna J, Hague F, Rodat-Despoix L, Geerts D, Leroy C, Tulasne D, Ouadid-Ahidouch H, Kischel P.

Cell Death Differ. 2018 Mar;25(4):691-705. doi: 10.1038/s41418-017-0007-1. Epub 2018 Jan 11.


ErbB3 drives mammary epithelial survival and differentiation during pregnancy and lactation.

Williams MM, Vaught DB, Joly MM, Hicks DJ, Sanchez V, Owens P, Rahman B, Elion DL, Balko JM, Cook RS.

Breast Cancer Res. 2017 Sep 8;19(1):105. doi: 10.1186/s13058-017-0893-7.


Development of a new analog of SGK1 inhibitor and its evaluation as a therapeutic molecule of colorectal cancer.

Liang X, Lan C, Zhou J, Fu W, Long X, An Y, Jiao G, Wang K, Li Y, Xu J, Huang Q, Xu B, Xiao J.

J Cancer. 2017 Jul 20;8(12):2256-2262. doi: 10.7150/jca.19566. eCollection 2017.


Expression of serum- and glucocorticoid-regulated kinase 1 and its association with clinicopathological factors and the survival of patients with adenocarcinoma of the esophagogastric junction.

Gao S, Wang D, Kong G, Li S, Wang W, Wang H, Zhou F.

Oncol Lett. 2017 May;13(5):3572-3578. doi: 10.3892/ol.2017.5927. Epub 2017 Mar 27.


PI3K signaling in cancer: beyond AKT.

Lien EC, Dibble CC, Toker A.

Curr Opin Cell Biol. 2017 Apr;45:62-71. doi: 10.1016/ Epub 2017 Mar 24. Review.


Molecular changes and signaling events occurring in spermatozoa during epididymal maturation.

Gervasi MG, Visconti PE.

Andrology. 2017 Mar;5(2):204-218. doi: 10.1111/andr.12320. Review.


SGK1: The Dark Side of PI3K Signaling.

Di Cristofano A.

Curr Top Dev Biol. 2017;123:49-71. doi: 10.1016/bs.ctdb.2016.11.006. Epub 2016 Dec 15. Review.


Insulin and SGK1 reduce the function of Na+/monocarboxylate transporter 1 (SMCT1/SLC5A8).

López-Barradas A, González-Cid T, Vázquez N, Gavi-Maza M, Reyes-Camacho A, Velázquez-Villegas LA, Ramírez V, Zandi-Nejad K, Mount DB, Torres N, Tovar AR, Romero MF, Gamba G, Plata C.

Am J Physiol Cell Physiol. 2016 Nov 1;311(5):C720-C734. doi: 10.1152/ajpcell.00104.2015. Epub 2016 Aug 3.


The hVps34-SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth.

Bago R, Sommer E, Castel P, Crafter C, Bailey FP, Shpiro N, Baselga J, Cross D, Eyers PA, Alessi DR.

EMBO J. 2016 Sep 1;35(17):1902-22. doi: 10.15252/embj.201693929. Epub 2016 Aug 1. Erratum in: EMBO J. 2016 Oct 17;35(20):2263.


PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition.

Castel P, Ellis H, Bago R, Toska E, Razavi P, Carmona FJ, Kannan S, Verma CS, Dickler M, Chandarlapaty S, Brogi E, Alessi DR, Baselga J, Scaltriti M.

Cancer Cell. 2016 Aug 8;30(2):229-242. doi: 10.1016/j.ccell.2016.06.004. Epub 2016 Jul 21.


Two new competing pathways establish the threshold for cyclin-B-Cdk1 activation at the meiotic G2/M transition.

Hiraoka D, Aono R, Hanada S, Okumura E, Kishimoto T.

J Cell Sci. 2016 Aug 15;129(16):3153-66. doi: 10.1242/jcs.182170. Epub 2016 Jul 7.


Role of SGK1 for fatty acid uptake, cell survival and radioresistance of NCI-H460 lung cancer cells exposed to acute or chronic cycling severe hypoxia.

Matschke J, Wiebeck E, Hurst S, Rudner J, Jendrossek V.

Radiat Oncol. 2016 Jun 1;11:75. doi: 10.1186/s13014-016-0647-1.


Dexamethasone and insulin activate serum and glucocorticoid-inducible kinase 1 (SGK1) via different molecular mechanisms in cortical collecting duct cells.

Mansley MK, Watt GB, Francis SL, Walker DJ, Land SC, Bailey MA, Wilson SM.

Physiol Rep. 2016 May;4(10). pii: e12792. doi: 10.14814/phy2.12792.


NDRG2 phosphorylation provides negative feedback for SGK1-dependent regulation of a kainate receptor in astrocytes.

Matschke V, Theiss C, Hollmann M, Schulze-Bahr E, Lang F, Seebohm G, Strutz-Seebohm N.

Front Cell Neurosci. 2015 Oct 6;9:387. doi: 10.3389/fncel.2015.00387. eCollection 2015.


Phosphoinositide dependent protein kinase 1 is required for exercise-induced cardiac hypertrophy but not the associated mitochondrial adaptations.

Noh J, Wende AR, Olsen CD, Kim B, Bevins J, Zhu Y, Zhang QJ, Riehle C, Abel ED.

J Mol Cell Cardiol. 2015 Dec;89(Pt B):297-305. doi: 10.1016/j.yjmcc.2015.10.015. Epub 2015 Oct 22.


Phosphatidylinositolphosphate phosphatase activities and cancer.

Rudge SA, Wakelam MJ.

J Lipid Res. 2016 Feb;57(2):176-92. doi: 10.1194/jlr.R059154. Epub 2015 Aug 24. Review.


SGK3 (CISK) may induce tumor angiogenesis (Hypothesis).

Hou M, Lai Y, He S, He W, Shen H, Ke Z.

Oncol Lett. 2015 Jul;10(1):23-26. Epub 2015 May 6.

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