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Items: 1 to 20 of 147


PIN1 Modulates Huntingtin Levels and Aggregate Accumulation: An In vitro Model.

Carnemolla A, Michelazzi S, Agostoni E.

Front Cell Neurosci. 2017 May 8;11:121. doi: 10.3389/fncel.2017.00121. eCollection 2017.


The alphabet of intrinsic disorder: I. Act like a Pro: On the abundance and roles of proline residues in intrinsically disordered proteins.

Theillet FX, Kalmar L, Tompa P, Han KH, Selenko P, Dunker AK, Daughdrill GW, Uversky VN.

Intrinsically Disord Proteins. 2013 Apr 1;1(1):e24360. doi: 10.4161/idp.24360. eCollection 2013 Jan-Dec. Review.


Dynamic regulation of Pin1 expression and function during zebrafish development.

Ibarra MS, Borini Etichetti C, Di Benedetto C, Rosano GL, Margarit E, Del Sal G, Mione M, Girardini J.

PLoS One. 2017 Apr 20;12(4):e0175939. doi: 10.1371/journal.pone.0175939. eCollection 2017.


The WW domain of the scaffolding protein IQGAP1 is neither necessary nor sufficient for binding to the MAPKs ERK1 and ERK2.

Bardwell AJ, Lagunes L, Zebarjedi R, Bardwell L.

J Biol Chem. 2017 May 26;292(21):8750-8761. doi: 10.1074/jbc.M116.767087. Epub 2017 Apr 10.


MicroRNA-140-5p inhibits hepatocellular carcinoma by directly targeting the unique isomerase Pin1 to block multiple cancer-driving pathways.

Yan X, Zhu Z, Xu S, Yang LN, Liao XH, Zheng M, Yang D, Wang J, Chen D, Wang L, Liu X, Liu J, Chen RH, Zhou XZ, Lu KP, Liu H.

Sci Rep. 2017 Apr 6;7:45915. doi: 10.1038/srep45915.


Characterization of E3 ligases involved in lysosomal sorting of the HIV-1 restriction factor BST2.

Roy N, Pacini G, Berlioz-Torrent C, Janvier K.

J Cell Sci. 2017 May 1;130(9):1596-1611. doi: 10.1242/jcs.195412. Epub 2017 Mar 20.


Missing-in-metastasis protein downregulates CXCR4 by promoting ubiquitylation and interaction with small Rab GTPases.

Li L, Baxter SS, Gu N, Ji M, Zhan X.

J Cell Sci. 2017 Apr 15;130(8):1475-1485. doi: 10.1242/jcs.198937. Epub 2017 Mar 6.


Fluorescent Reporters and Biosensors for Probing the Dynamic Behavior of Protein Kinases.

González-Vera JA, Morris MC.

Proteomes. 2015 Nov 4;3(4):369-410. doi: 10.3390/proteomes3040369. Review.


Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis.

Xu T, Zhang H, Park SS, Venneti S, Kuick R, Ha K, Michael LE, Santi M, Uchida C, Uchida T, Srinivasan A, Olson JM, Dlugosz AA, Camelo-Piragua S, Rual JF.

Neoplasia. 2017 Mar;19(3):216-225. doi: 10.1016/j.neo.2017.01.002. Epub 2017 Feb 3.


Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation.

Nazio F, Carinci M, Valacca C, Bielli P, Strappazzon F, Antonioli M, Ciccosanti F, Rodolfo C, Campello S, Fimia GM, Sette C, Bonaldo P, Cecconi F.

J Cell Biol. 2016 Dec 19;215(6):841-856. Epub 2016 Dec 8.


Loss of NEDD4 contributes to RTP801 elevation and neuron toxicity: implications for Parkinson's disease.

Canal M, Martín-Flores N, Pérez-Sisqués L, Romaní-Aumedes J, Altas B, Man HY, Kawabe H, Alberch J, Malagelada C.

Oncotarget. 2016 Sep 13;7(37):58813-58831. doi: 10.18632/oncotarget.11020.


NmPin from the marine thaumarchaeote Nitrosopumilus maritimus is an active membrane associated prolyl isomerase.

Hoppstock L, Trusch F, Lederer C, van West P, Koenneke M, Bayer P.

BMC Biol. 2016 Jun 27;14:53. doi: 10.1186/s12915-016-0274-1.


SETD2: an epigenetic modifier with tumor suppressor functionality.

Li J, Duns G, Westers H, Sijmons R, van den Berg A, Kok K.

Oncotarget. 2016 Aug 2;7(31):50719-50734. doi: 10.18632/oncotarget.9368. Review.


Ubiquitin ligase Nedd4-2 modulates Kv1.3 current amplitude and ion channel protein targeting.

Vélez P, Schwartz AB, Iyer SR, Warrington A, Fadool DA.

J Neurophysiol. 2016 Aug 1;116(2):671-85. doi: 10.1152/jn.00874.2015. Epub 2016 May 4.


TNFα reduces eNOS activity in endothelial cells through serine 116 phosphorylation and Pin1 binding: Confirmation of a direct, inhibitory interaction of Pin1 with eNOS.

Kennard S, Ruan L, Buffett RJ, Fulton D, Venema RC.

Vascul Pharmacol. 2016 Jun;81:61-8. doi: 10.1016/j.vph.2016.04.003. Epub 2016 Apr 9.


The challenge of ORF1p phosphorylation: Effects on L1 activity and its host.

Furano AV, Cook PR.

Mob Genet Elements. 2015 Dec 4;6(1):e1119927. eCollection 2016 Jan-Feb.


Protein Allostery and Conformational Dynamics.

Guo J, Zhou HX.

Chem Rev. 2016 Jun 8;116(11):6503-15. doi: 10.1021/acs.chemrev.5b00590. Epub 2016 Feb 15. Review.


Pre-Anchoring of Pin1 to Unphosphorylated c-Myc in a Fuzzy Complex Regulates c-Myc Activity.

Helander S, Montecchio M, Pilstål R, Su Y, Kuruvilla J, Elvén M, Ziauddin JM, Anandapadamanaban M, Cristobal S, Lundström P, Sears RC, Wallner B, Sunnerhagen M.

Structure. 2015 Dec 1;23(12):2267-79. doi: 10.1016/j.str.2015.10.010. Epub 2015 Nov 19.


Investigating Dynamic Interdomain Allostery in Pin1.

Peng JW.

Biophys Rev. 2015 Jun 1;7(2):239-249. Epub 2015 Apr 22.

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