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Items: 1 to 20 of 349

1.

Geminin deficiency enhances survival in a murine medulloblastoma model by inducing apoptosis of preneoplastic granule neuron precursors.

Sankar S, Patterson E, Lewis EM, Waller LE, Tong C, Dearborn J, Wozniak D, Rubin JB, Kroll KL.

Genes Cancer. 2017 Sep;8(9-10):725-744. doi: 10.18632/genesandcancer.157.

2.

Obstacles to Brain Tumor Therapy: Key ABC Transporters.

Wijaya J, Fukuda Y, Schuetz JD.

Int J Mol Sci. 2017 Nov 27;18(12). pii: E2544. doi: 10.3390/ijms18122544. Review.

3.

mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma.

Wu CC, Hou S, Orr BA, Kuo BR, Youn YH, Ong T, Roth F, Eberhart CG, Robinson GW, Solecki DJ, Taketo MM, Gilbertson RJ, Roussel MF, Han YG.

Dev Cell. 2017 Dec 18;43(6):673-688.e5. doi: 10.1016/j.devcel.2017.10.011. Epub 2017 Nov 2.

PMID:
29103956
4.

Nanog-driven cell-reprogramming and self-renewal maintenance in Ptch1 +/- granule cell precursors after radiation injury.

Tanno B, Leonardi S, Babini G, Giardullo P, De Stefano I, Pasquali E, Saran A, Mancuso M.

Sci Rep. 2017 Oct 27;7(1):14238. doi: 10.1038/s41598-017-14506-6.

5.

Astrocytes Promote Medulloblastoma Progression through Hedgehog Secretion.

Liu Y, Yuelling LW, Wang Y, Du F, Gordon RE, O'Brien JA, Ng JMY, Robins S, Lee EH, Liu H, Curran T, Yang ZJ.

Cancer Res. 2017 Dec 1;77(23):6692-6703. doi: 10.1158/0008-5472.CAN-17-1463. Epub 2017 Oct 6.

PMID:
28986380
6.

Lkb1 regulates granule cell migration and cortical folding of the cerebellar cortex.

Ryan KE, Kim PS, Fleming JT, Brignola E, Cheng FY, Litingtung Y, Chiang C.

Dev Biol. 2017 Dec 1;432(1):165-177. doi: 10.1016/j.ydbio.2017.09.036. Epub 2017 Sep 30.

PMID:
28974424
7.

Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects.

De Mori R, Romani M, D'Arrigo S, Zaki MS, Lorefice E, Tardivo S, Biagini T, Stanley V, Musaev D, Fluss J, Micalizzi A, Nuovo S, Illi B, Chiapparini L, Di Marcotullio L, Issa MY, Anello D, Casella A, Ginevrino M, Leggins AS, Roosing S, Alfonsi R, Rosati J, Schot R, Mancini GMS, Bertini E, Dobyns WB, Mazza T, Gleeson JG, Valente EM.

Am J Hum Genet. 2017 Oct 5;101(4):552-563. doi: 10.1016/j.ajhg.2017.08.017. Epub 2017 Sep 28.

PMID:
28965847
8.

Zfp423/ZNF423 regulates cell cycle progression, the mode of cell division and the DNA-damage response in Purkinje neuron progenitors.

Casoni F, Croci L, Bosone C, D'Ambrosio R, Badaloni A, Gaudesi D, Barili V, Sarna JR, Tessarollo L, Cremona O, Hawkes R, Warming S, Consalez GG.

Development. 2017 Oct 15;144(20):3686-3697. doi: 10.1242/dev.155077. Epub 2017 Sep 11.

PMID:
28893945
9.

An RNA interference screen identifies druggable regulators of MeCP2 stability.

Lombardi LM, Zaghlula M, Sztainberg Y, Baker SA, Klisch TJ, Tang AA, Huang EJ, Zoghbi HY.

Sci Transl Med. 2017 Aug 23;9(404). pii: eaaf7588. doi: 10.1126/scitranslmed.aaf7588.

PMID:
28835516
10.

Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system.

Han Y, Xiong Y, Shi X, Wu J, Zhao Y, Jiang J.

PLoS Biol. 2017 Aug 4;15(8):e2002063. doi: 10.1371/journal.pbio.2002063. eCollection 2017 Aug.

11.

Maml1 acts cooperatively with Gli proteins to regulate sonic hedgehog signaling pathway.

Quaranta R, Pelullo M, Zema S, Nardozza F, Checquolo S, Lauer DM, Bufalieri F, Palermo R, Felli MP, Vacca A, Talora C, Di Marcotullio L, Screpanti I, Bellavia D.

Cell Death Dis. 2017 Jul 20;8(7):e2942. doi: 10.1038/cddis.2017.326.

12.

Neuronal Activity in Ontogeny and Oncology.

Venkatesh H, Monje M.

Trends Cancer. 2017 Feb;3(2):89-112. doi: 10.1016/j.trecan.2016.12.008. Epub 2017 Feb 13. Review.

PMID:
28718448
13.

DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia.

Ding J, Shao L, Yao Y, Tong X, Liu H, Yue S, Xie L, Cheng SY.

Sci Rep. 2017 Jul 13;7(1):5296. doi: 10.1038/s41598-017-05680-8.

14.

Phase I study of oral sonidegib (LDE225) in pediatric brain and solid tumors and a phase II study in children and adults with relapsed medulloblastoma.

Kieran MW, Chisholm J, Casanova M, Brandes AA, Aerts I, Bouffet E, Bailey S, Leary S, MacDonald TJ, Mechinaud F, Cohen KJ, Riccardi R, Mason W, Hargrave D, Kalambakas S, Deshpande P, Tai F, Hurh E, Geoerger B.

Neuro Oncol. 2017 Oct 19;19(11):1542-1552. doi: 10.1093/neuonc/nox109.

PMID:
28605510
15.

Pyruvate Kinase Inhibits Proliferation during Postnatal Cerebellar Neurogenesis and Suppresses Medulloblastoma Formation.

Tech K, Tikunov AP, Farooq H, Morrissy AS, Meidinger J, Fish T, Green SC, Liu H, Li Y, Mungall AJ, Moore RA, Ma Y, Jones SJM, Marra MA, Vander Heiden MG, Taylor MD, Macdonald JM, Gershon TR.

Cancer Res. 2017 Jun 15;77(12):3217-3230. doi: 10.1158/0008-5472.CAN-16-3304. Epub 2017 May 17.

PMID:
28515149
16.

Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia.

Heng X, Guo Q, Leung AW, Li JY.

Elife. 2017 May 10;6. pii: e23253. doi: 10.7554/eLife.23253.

17.

Extracellular Regulation of the Mitotic Spindle and Fate Determinants Driving Asymmetric Cell Division.

Smith P, Azzam M, Hinck L.

Results Probl Cell Differ. 2017;61:351-373. doi: 10.1007/978-3-319-53150-2_16. Review.

18.

The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression.

Whittaker DE, Riegman KL, Kasah S, Mohan C, Yu T, Sala BP, Hebaishi H, Caruso A, Marques AC, Michetti C, Smachetti ME, Shah A, Sabbioni M, Kulhanci O, Tee WW, Reinberg D, Scattoni ML, Volk H, McGonnell I, Wardle FC, Fernandes C, Basson MA.

J Clin Invest. 2017 Mar 1;127(3):874-887. doi: 10.1172/JCI83408. Epub 2017 Feb 6.

19.

Trafficking to the primary cilium membrane.

Mukhopadhyay S, Badgandi HB, Hwang SH, Somatilaka B, Shimada IS, Pal K.

Mol Biol Cell. 2017 Jan 15;28(2):233-239. doi: 10.1091/mbc.E16-07-0505. Review.

20.

Reprogramming Medulloblastoma-Propagating Cells by a Combined Antagonism of Sonic Hedgehog and CXCR4.

Ward SA, Warrington NM, Taylor S, Kfoury N, Luo J, Rubin JB.

Cancer Res. 2017 Mar 15;77(6):1416-1426. doi: 10.1158/0008-5472.CAN-16-0847. Epub 2016 Dec 28.

PMID:
28031228

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