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Items: 1 to 20 of 167

1.
2.

Structural and functional characteristics of Dyrk, a novel subfamily of protein kinases with dual specificity.

Becker W, Joost HG.

Prog Nucleic Acid Res Mol Biol. 1999;62:1-17. Review.

PMID:
9932450
3.

Specificity determinants of substrate recognition by the protein kinase DYRK1A.

Himpel S, Tegge W, Frank R, Leder S, Joost HG, Becker W.

J Biol Chem. 2000 Jan 28;275(4):2431-8.

4.

Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII.

Kentrup H, Becker W, Heukelbach J, Wilmes A, Schürmann A, Huppertz C, Kainulainen H, Joost HG.

J Biol Chem. 1996 Feb 16;271(7):3488-95.

5.

Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases.

Leder S, Weber Y, Altafaj X, Estivill X, Joost HG, Becker W.

Biochem Biophys Res Commun. 1999 Jan 19;254(2):474-9.

PMID:
9918863
6.

Splice variants of the dual specificity tyrosine phosphorylation-regulated kinase 4 (DYRK4) differ in their subcellular localization and catalytic activity.

Papadopoulos C, Arato K, Lilienthal E, Zerweck J, Schutkowski M, Chatain N, Müller-Newen G, Becker W, de la Luna S.

J Biol Chem. 2011 Feb 18;286(7):5494-505. doi: 10.1074/jbc.M110.157909. Epub 2010 Dec 2.

7.

Mechanism of dual specificity kinase activity of DYRK1A.

Walte A, Rüben K, Birner-Gruenberger R, Preisinger C, Bamberg-Lemper S, Hilz N, Bracher F, Becker W.

FEBS J. 2013 Sep;280(18):4495-511. doi: 10.1111/febs.12411. Epub 2013 Jul 22.

8.

Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors.

de Graaf K, Hekerman P, Spelten O, Herrmann A, Packman LC, Büssow K, Müller-Newen G, Becker W.

J Biol Chem. 2004 Feb 6;279(6):4612-24. Epub 2003 Nov 17.

10.

Cloning of a human homolog of the Drosophila minibrain/rat Dyrk gene from "the Down syndrome critical region" of chromosome 21.

Shindoh N, Kudoh J, Maeda H, Yamaki A, Minoshima S, Shimizu Y, Shimizu N.

Biochem Biophys Res Commun. 1996 Aug 5;225(1):92-9.

PMID:
8769099
11.

Phosphorylation of amphiphysin I by minibrain kinase/dual-specificity tyrosine phosphorylation-regulated kinase, a kinase implicated in Down syndrome.

Murakami N, Xie W, Lu RC, Chen-Hwang MC, Wieraszko A, Hwang YW.

J Biol Chem. 2006 Aug 18;281(33):23712-24. Epub 2006 May 29.

12.

Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation.

Göckler N, Jofre G, Papadopoulos C, Soppa U, Tejedor FJ, Becker W.

FEBS J. 2009 Nov;276(21):6324-37. doi: 10.1111/j.1742-4658.2009.07346.x. Epub 2009 Oct 1.

13.

The Down syndrome candidate dual-specificity tyrosine phosphorylation-regulated kinase 1A phosphorylates the neurodegeneration-related septin 4.

Sitz JH, Baumgärtel K, Hämmerle B, Papadopoulos C, Hekerman P, Tejedor FJ, Becker W, Lutz B.

Neuroscience. 2008 Dec 2;157(3):596-605. doi: 10.1016/j.neuroscience.2008.09.034. Epub 2008 Oct 1.

PMID:
18938227
14.

Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome "critical region".

Song WJ, Sternberg LR, Kasten-Sportès C, Keuren ML, Chung SH, Slack AC, Miller DE, Glover TW, Chiang PW, Lou L, Kurnit DM.

Genomics. 1996 Dec 15;38(3):331-9.

PMID:
8975710
15.

Phosphorylation of Ser640 in muscle glycogen synthase by DYRK family protein kinases.

Skurat AV, Dietrich AD.

J Biol Chem. 2004 Jan 23;279(4):2490-8. Epub 2003 Oct 30.

16.

[Molecular cloning and characterization of novel protein kinase gene DYRK3].

Xia J, Yang X, Ruan Q, Pan Q, Liu C, Xie W, Deng H.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 1998 Dec 10;15(6):327-32. Chinese.

PMID:
9845759
17.

Unusual function of the activation loop in the protein kinase DYRK1A.

Wiechmann S, Czajkowska H, de Graaf K, Grötzinger J, Joost HG, Becker W.

Biochem Biophys Res Commun. 2003 Mar 7;302(2):403-8.

PMID:
12604362
18.

Dynamin is a minibrain kinase/dual specificity Yak1-related kinase 1A substrate.

Chen-Hwang MC, Chen HR, Elzinga M, Hwang YW.

J Biol Chem. 2002 May 17;277(20):17597-604. Epub 2002 Mar 4.

19.

dDYRK2: a novel dual-specificity tyrosine-phosphorylation-regulated kinase in Drosophila.

Lochhead PA, Sibbet G, Kinstrie R, Cleghon T, Rylatt M, Morrison DK, Cleghon V.

Biochem J. 2003 Sep 1;374(Pt 2):381-91.

20.

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