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One face of a transmembrane helix is crucial in mechanosensitive channel gating.

Ou X, Blount P, Hoffman RJ, Kung C.

Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11471-5.


Single residue substitutions that change the gating properties of a mechanosensitive channel in Escherichia coli.

Blount P, Sukharev SI, Schroeder MJ, Nagle SK, Kung C.

Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11652-7.


Hydrophilicity of a single residue within MscL correlates with increased channel mechanosensitivity.

Yoshimura K, Batiza A, Schroeder M, Blount P, Kung C.

Biophys J. 1999 Oct;77(4):1960-72.


On the structure of the N-terminal domain of the MscL channel: helical bundle or membrane interface.

Iscla I, Wray R, Blount P.

Biophys J. 2008 Sep;95(5):2283-91. doi: 10.1529/biophysj.107.127423. Epub 2008 May 30.


Mutations in a bacterial mechanosensitive channel change the cellular response to osmotic stress.

Blount P, Schroeder MJ, Kung C.

J Biol Chem. 1997 Dec 19;272(51):32150-7.


Genetic screen for potassium leaky small mechanosensitive channels (MscS) in Escherichia coli: recognition of cytoplasmic β domain as a new gating element.

Koprowski P, Grajkowski W, Isacoff EY, Kubalski A.

J Biol Chem. 2011 Jan 7;286(1):877-88. doi: 10.1074/jbc.M110.176131. Epub 2010 Oct 26.


Phosphatidylinositol is crucial for the mechanosensitivity of Mycobacterium tuberculosis MscL.

Zhong D, Blount P.

Biochemistry. 2013 Aug 13;52(32):5415-20. doi: 10.1021/bi400790j. Epub 2013 Aug 1.


Correlating a protein structure with function of a bacterial mechanosensitive channel.

Moe PC, Levin G, Blount P.

J Biol Chem. 2000 Oct 6;275(40):31121-7.


Scanning MscL Channels with Targeted Post-Translational Modifications for Functional Alterations.

Iscla I, Wray R, Eaton C, Blount P.

PLoS One. 2015 Sep 14;10(9):e0137994. doi: 10.1371/journal.pone.0137994. eCollection 2015.


Structure of the MscL homolog from Mycobacterium tuberculosis: a gated mechanosensitive ion channel.

Chang G, Spencer RH, Lee AT, Barclay MT, Rees DC.

Science. 1998 Dec 18;282(5397):2220-6.


Purification and functional reconstitution of N- and C-halves of the MscL channel.

Park KH, Berrier C, Martinac B, Ghazi A.

Biophys J. 2004 Apr;86(4):2129-36.


'Feeling the pressure': structural insights into a gated mechanosensitive channel.

Spencer RH, Chang G, Rees DC.

Curr Opin Struct Biol. 1999 Aug;9(4):448-54. Review. Erratum in: Curr Opin Struct Biol 1999 Oct;9(5):650-1.


On the conformation of the COOH-terminal domain of the large mechanosensitive channel MscL.

Anishkin A, Gendel V, Sharifi NA, Chiang CS, Shirinian L, Guy HR, Sukharev S.

J Gen Physiol. 2003 Mar;121(3):227-44.

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