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Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death.

Gross A, Yin XM, Wang K, Wei MC, Jockel J, Milliman C, Erdjument-Bromage H, Tempst P, Korsmeyer SJ.

J Biol Chem. 1999 Jan 8;274(2):1156-63.


Caspases induce cytochrome c release from mitochondria by activating cytosolic factors.

Bossy-Wetzel E, Green DR.

J Biol Chem. 1999 Jun 18;274(25):17484-90.


Bid-induced cytochrome c release is mediated by a pathway independent of mitochondrial permeability transition pore and Bax.

Kim TH, Zhao Y, Barber MJ, Kuharsky DK, Yin XM.

J Biol Chem. 2000 Dec 15;275(50):39474-81.


Regulation of intracellular pH mediates Bax activation in HeLa cells treated with staurosporine or tumor necrosis factor-alpha.

Tafani M, Cohn JA, Karpinich NO, Rothman RJ, Russo MA, Farber JL.

J Biol Chem. 2002 Dec 20;277(51):49569-76. Epub 2002 Oct 18.


Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria.

Guo Y, Srinivasula SM, Druilhe A, Fernandes-Alnemri T, Alnemri ES.

J Biol Chem. 2002 Apr 19;277(16):13430-7. Epub 2002 Feb 6.


Bid induces cytochrome c-impermeable Bax channels in liposomes.

Roucou X, Rostovtseva T, Montessuit S, Martinou JC, Antonsson B.

Biochem J. 2002 May 1;363(Pt 3):547-52.


Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis.

Fulda S, Meyer E, Friesen C, Susin SA, Kroemer G, Debatin KM.

Oncogene. 2001 Mar 1;20(9):1063-75.


Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis.

Yin XM, Wang K, Gross A, Zhao Y, Zinkel S, Klocke B, Roth KA, Korsmeyer SJ.

Nature. 1999 Aug 26;400(6747):886-91.


Analysis of apoptotic and antiapoptotic signalling pathways induced by Helicobacter pylori.

Maeda S, Yoshida H, Mitsuno Y, Hirata Y, Ogura K, Shiratori Y, Omata M.

Gut. 2002 Jun;50(6):771-8.


The destabilization of lipid membranes induced by the C-terminal fragment of caspase 8-cleaved bid is inhibited by the N-terminal fragment.

Kudla G, Montessuit S, Eskes R, Berrier C, Martinou JC, Ghazi A, Antonsson B.

J Biol Chem. 2000 Jul 28;275(30):22713-8.


Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8.

Desagher S, Osen-Sand A, Montessuit S, Magnenat E, Vilbois F, Hochmann A, Journot L, Antonsson B, Martinou JC.

Mol Cell. 2001 Sep;8(3):601-11.


Polyamine depletion prevents camptothecin-induced apoptosis by inhibiting the release of cytochrome c.

Yuan Q, Ray RM, Johnson LR.

Am J Physiol Cell Physiol. 2002 Jun;282(6):C1290-7.


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