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Items: 1 to 20 of 139

1.

Human buprenorphine N-dealkylation is catalyzed by cytochrome P450 3A4.

Kobayashi K, Yamamoto T, Chiba K, Tani M, Shimada N, Ishizaki T, Kuroiwa Y.

Drug Metab Dispos. 1998 Aug;26(8):818-21.

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Identification of CYP3A4 as the enzyme involved in the mono-N-dealkylation of disopyramide enantiomers in humans.

Echizen H, Tanizaki M, Tatsuno J, Chiba K, Berwick T, Tani M, Gonzalez FJ, Ishizaki T.

Drug Metab Dispos. 2000 Aug;28(8):937-44.

4.

Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil N-dealkylation.

Tateishi T, Krivoruk Y, Ueng YF, Wood AJ, Guengerich FP, Wood M.

Anesth Analg. 1996 Jan;82(1):167-72.

PMID:
8712396
5.

Role of a potent inhibitory monoclonal antibody to cytochrome P-450 3A4 in assessment of human drug metabolism.

Mei Q, Tang C, Assang C, Lin Y, Slaughter D, Rodrigues AD, Baillie TA, Rushmore TH, Shou M.

J Pharmacol Exp Ther. 1999 Nov;291(2):749-59.

6.

Characterization of the cytochrome P450 isoenzymes involved in the in vitro N-dealkylation of haloperidol.

Pan LP, Wijnant P, De Vriendt C, Rosseel MT, Belpaire FM.

Br J Clin Pharmacol. 1997 Dec;44(6):557-64.

7.

Identification of CYP3A4 as the principal enzyme catalyzing mifepristone (RU 486) oxidation in human liver microsomes.

Jang GR, Wrighton SA, Benet LZ.

Biochem Pharmacol. 1996 Sep 13;52(5):753-61.

PMID:
8765473
8.

Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.

Renwick AB, Surry D, Price RJ, Lake BG, Evans DC.

Xenobiotica. 2000 Oct;30(10):955-69.

PMID:
11315104
9.

Role of human cytochrome P450 3A4 in metabolism of medroxyprogesterone acetate.

Kobayashi K, Mimura N, Fujii H, Minami H, Sasaki Y, Shimada N, Chiba K.

Clin Cancer Res. 2000 Aug;6(8):3297-303.

10.

Metabolism of risperidone to 9-hydroxyrisperidone by human cytochromes P450 2D6 and 3A4.

Fang J, Bourin M, Baker GB.

Naunyn Schmiedebergs Arch Pharmacol. 1999 Feb;359(2):147-51.

PMID:
10048600
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Metabolism of fentanyl, a synthetic opioid analgesic, by human liver microsomes. Role of CYP3A4.

Feierman DE, Lasker JM.

Drug Metab Dispos. 1996 Sep;24(9):932-9.

PMID:
8886601
14.

Involvement of CYP1A2 and CYP3A4 in lidocaine N-deethylation and 3-hydroxylation in humans.

Wang JS, Backman JT, Taavitsainen P, Neuvonen PJ, Kivistö KT.

Drug Metab Dispos. 2000 Aug;28(8):959-65.

15.

Inhibition of human cytochrome P450 enzymes by 1,4-dihydropyridine calcium antagonists: prediction of in vivo drug-drug interactions.

Katoh M, Nakajima M, Shimada N, Yamazaki H, Yokoi T.

Eur J Clin Pharmacol. 2000 Feb-Mar;55(11-12):843-52.

PMID:
10805063
16.

Involvement of cytochrome P450 3A4 in N-dealkylation of buprenorphine in human liver microsomes.

Iribarne C, Picart D, Dréano Y, Bail JP, Berthou F.

Life Sci. 1997;60(22):1953-64.

PMID:
9180349
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Metabolism of 2,5-bis(trifluoromethyl)-7-benzyloxy-4-trifluoromethylcoumarin by human hepatic CYP isoforms: evidence for selectivity towards CYP3A4.

Renwick AB, Lewis DF, Fulford S, Surry D, Williams B, Worboys PD, Cai X, Wang RW, Price RJ, Lake BG, Evans DC.

Xenobiotica. 2001 Apr;31(4):187-204.

PMID:
11465405
20.

[O-methyl 14C]naproxen O-demethylase activity in human liver microsomes: evidence for the involvement of cytochrome P4501A2 and P4502C9/10.

Rodrigues AD, Kukulka MJ, Roberts EM, Ouellet D, Rodgers TR.

Drug Metab Dispos. 1996 Jan;24(1):126-36.

PMID:
8825200

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