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Cytosine deaminase adenoviral vector and 5-fluorocytosine selectively reduce breast cancer cells 1 million-fold when they contaminate hematopoietic cells: a potential purging method for autologous transplantation.

Garcia-Sanchez F, Pizzorno G, Fu SQ, Nanakorn T, Krause DS, Liang J, Adams E, Leffert JJ, Yin LH, Cooperberg MR, Hanania E, Wang WL, Won JH, Peng XY, Cote R, Brown R, Burtness B, Giles R, Crystal R, Deisseroth AB.

Blood. 1998 Jul 15;92(2):672-82.


Molecular chemotherapy combined with radiation therapy enhances killing of cholangiocarcinoma cells in vitro and in vivo.

Pederson LC, Buchsbaum DJ, Vickers SM, Kancharla SR, Mayo MS, Curiel DT, Stackhouse MA.

Cancer Res. 1997 Oct 1;57(19):4325-32.


The use of the L-plastin promoter for adenoviral-mediated, tumor-specific gene expression in ovarian and bladder cancer cell lines.

Peng XY, Won JH, Rutherford T, Fujii T, Zelterman D, Pizzorno G, Sapi E, Leavitt J, Kacinski B, Crystal R, Schwartz P, Deisseroth A.

Cancer Res. 2001 Jun 1;61(11):4405-13.


Efficient and nontoxic adenoviral purging method for autologous transplantation in breast cancer patients.

Lillo R, Ramírez M, Alvarez A, Santos S, García-Castro J, Fernández de Velasco J, Avilés MJ, Gómez-Pineda A, Díez JL, Balas A, Vicario JL, Bueren JA, García-Sánchez F.

Cancer Res. 2002 Sep 1;62(17):5013-8.


Breast cancer-specific expression of the Candida albicans cytosine deaminase gene using a transcriptional targeting approach.

Anderson LM, Krotz S, Weitzman SA, Thimmapaya B.

Cancer Gene Ther. 2000 Jun;7(6):845-52.


Combined antitumor effects of an adenoviral cytosine deaminase/thymidine kinase fusion gene in rat C6 glioma.

Chang JW, Lee H, Kim E, Lee Y, Chung SS, Kim JH.

Neurosurgery. 2000 Oct;47(4):931-8; discussion 938-9.


Purging of contaminating breast cancer cells from hematopoietic stem cell grafts by adenoviral GAL-TEK gene therapy and magnetic antibody cell separation.

Marini FC, Snell V, Yu Q, Zhang X, Singletary SE, Champlin R, Andreeff M.

Clin Cancer Res. 1999 Jun;5(6):1557-68.


Virally directed cytosine deaminase/5-fluorocytosine gene therapy enhances radiation response in human cancer xenografts.

Hanna NN, Mauceri HJ, Wayne JD, Hallahan DE, Kufe DW, Weichselbaum RR.

Cancer Res. 1997 Oct 1;57(19):4205-9.


Cytosine deaminase-producing human mesenchymal stem cells mediate an antitumor effect in a mouse xenograft model.

You MH, Kim WJ, Shim W, Lee SR, Lee G, Choi S, Kim DY, Kim YM, Kim H, Han SU.

J Gastroenterol Hepatol. 2009 Aug;24(8):1393-400. doi: 10.1111/j.1440-1746.2009.05862.x. Epub 2009 May 28.


Sensitization of prostate cancer cell lines to 5-fluorocytosine induced by adenoviral vector carrying a CD transcription unit.

Yin L, Fu S, Wang X, Nanakorn T, Won J, Deisseroth A.

Chin Med J (Engl). 2001 Sep;114(9):972-5.


In vivo adenoviral-mediated gene transfer in the treatment of pancreatic cancer.

Evoy D, Hirschowitz EA, Naama HA, Li XK, Crystal RG, Daly JM, Lieberman MD.

J Surg Res. 1997 Apr;69(1):226-31.


In vivo gene therapy for colon cancer using adenovirus-mediated, transfer of the fusion gene cytosine deaminase and uracil phosphoribosyltransferase.

Chung-Faye GA, Chen MJ, Green NK, Burton A, Anderson D, Mautner V, Searle PF, Kerr DJ.

Gene Ther. 2001 Oct;8(20):1547-54.


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