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Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation.

Hu Y, Benedict MA, Wu D, Inohara N, Núñez G.

Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4386-91.


Failure of Bcl-2 family members to interact with Apaf-1 in normal and apoptotic cells.

Conus S, Rossé T, Borner C.

Cell Death Differ. 2000 Oct;7(10):947-54.


Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex.

Pan G, O'Rourke K, Dixit VM.

J Biol Chem. 1998 Mar 6;273(10):5841-5.


Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1.

Chau BN, Cheng EH, Kerr DA, Hardwick JM.

Mol Cell. 2000 Jul;6(1):31-40.


Identification of a Bcl-XL binding region within the ATPase domain of Apaf-1.

Yajima H, Suzuki F.

Biochem Biophys Res Commun. 2003 Sep 26;309(3):520-7.


Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death.

Chinnaiyan AM, O'Rourke K, Lane BR, Dixit VM.

Science. 1997 Feb 21;275(5303):1122-6.


Boo, a novel negative regulator of cell death, interacts with Apaf-1.

Song Q, Kuang Y, Dixit VM, Vincenz C.

EMBO J. 1999 Jan 4;18(1):167-78.


Bcl-xL does not inhibit the function of Apaf-1.

Newmeyer DD, Bossy-Wetzel E, Kluck RM, Wolf BB, Beere HM, Green DR.

Cell Death Differ. 2000 Apr;7(4):402-7.


Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1.

Moriishi K, Huang DC, Cory S, Adams JM.

Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9683-8.


Bcl-2 expression in neural cells blocks activation of ICE/CED-3 family proteases during apoptosis.

Srinivasan A, Foster LM, Testa MP, Ord T, Keane RW, Bredesen DE, Kayalar C.

J Neurosci. 1996 Sep 15;16(18):5654-60.


Acceleration of apoptotic cell death after the cleavage of Bcl-XL protein by caspase-3-like proteases.

Fujita N, Nagahashi A, Nagashima K, Rokudai S, Tsuruo T.

Oncogene. 1998 Sep 10;17(10):1295-304.


Cap-independent translation promotes C. elegans germ cell apoptosis through Apaf-1/CED-4 in a caspase-dependent mechanism.

Contreras V, Friday AJ, Morrison JK, Hao E, Keiper BD.

PLoS One. 2011;6(9):e24444. doi: 10.1371/journal.pone.0024444. Epub 2011 Sep 1.


Mitochondria and apoptosis.

Mignotte B, Vayssiere JL.

Eur J Biochem. 1998 Feb 15;252(1):1-15. Review.


Bcl-xL functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells.

Srinivasan A, Li F, Wong A, Kodandapani L, Smidt R Jr, Krebs JF, Fritz LC, Wu JC, Tomaselli KJ.

J Biol Chem. 1998 Feb 20;273(8):4523-9.

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