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Items: 1 to 20 of 211

1.

Mechanism of phosphatidylinositol-specific phospholipase C: a unified view of the mechanism of catalysis.

Hondal RJ, Zhao Z, Kravchuk AV, Liao H, Riddle SR, Yue X, Bruzik KS, Tsai MD.

Biochemistry. 1998 Mar 31;37(13):4568-80.

PMID:
9521777
2.

Involvement of the Arg-Asp-His catalytic triad in enzymatic cleavage of the phosphodiester bond.

Kubiak RJ, Yue X, Hondal RJ, Mihai C, Tsai MD, Bruzik KS.

Biochemistry. 2001 May 8;40(18):5422-32.

PMID:
11331006
3.

Phosphatidylinositol-specific phospholipase C: kinetic and stereochemical evidence for an interaction between arginine-69 and the phosphate group of phosphatidylinositol.

Hondal RJ, Riddle SR, Kravchuk AV, Zhao Z, Liao H, Bruzik KS, Tsai MD.

Biochemistry. 1997 Jun 3;36(22):6633-42.

PMID:
9184143
6.

Probing the roles of active site residues in phosphatidylinositol-specific phospholipase C from Bacillus cereus by site-directed mutagenesis.

Gässler CS, Ryan M, Liu T, Griffith OH, Heinz DW.

Biochemistry. 1997 Oct 21;36(42):12802-13.

PMID:
9335537
8.

Mechanism of phosphatidylinositol-specific phospholipase C: origin of unusually high nonbridging thio effects.

Kravchuk AV, Zhao L, Kubiak RJ, Bruzik KS, Tsai MD.

Biochemistry. 2001 May 8;40(18):5433-9.

PMID:
11331007
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11.

Application of Brønsted-type LFER in the study of the phospholipase C mechanism.

Mihai C, Kravchuk AV, Tsai MD, Bruzik KS.

J Am Chem Soc. 2003 Mar 19;125(11):3236-42.

PMID:
12630878
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13.

Phosphatidylinositol 4,5-bisphosphate binding to the pleckstrin homology domain of phospholipase C-delta1 enhances enzyme activity.

Lomasney JW, Cheng HF, Wang LP, Kuan Y, Liu S, Fesik SW, King K.

J Biol Chem. 1996 Oct 11;271(41):25316-26.

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Cloning and identification of amino acid residues of human phospholipase C delta 1 essential for catalysis.

Cheng HF, Jiang MJ, Chen CL, Liu SM, Wong LP, Lomasney JW, King K.

J Biol Chem. 1995 Mar 10;270(10):5495-505.

20.

Kinetic, stereochemical, and structural effects of mutations of the active site arginine residues in 4-oxalocrotonate tautomerase.

Harris TK, Czerwinski RM, Johnson WH Jr, Legler PM, Abeygunawardana C, Massiah MA, Stivers JT, Whitman CP, Mildvan AS.

Biochemistry. 1999 Sep 21;38(38):12343-57.

PMID:
10493802
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