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Items: 1 to 20 of 84

1.

Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase.

Kwon HJ, Owa T, Hassig CA, Shimada J, Schreiber SL.

Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3356-61.

2.

Synthesis and cellular characterization of the detransformation agent, (-)-depudecin.

Shimada J, Kwon HJ, Sawamura M, Schreiber SL.

Chem Biol. 1995 Aug;2(8):517-25.

3.

A novel compound, depudecin, induces production of transformation to the flat phenotype of NIH3T3 cells transformed by ras-oncogene.

Sugita K, Yoshida H, Matsumoto M, Matsutani S.

Biochem Biophys Res Commun. 1992 Jan 15;182(1):379-87.

PMID:
1731795
4.

Anti-parasitic activity of depudecin on Neospora caninum via the inhibition of histone deacetylase.

Kwon HJ, Kim JH, Kim M, Lee JK, Hwang WS, Kim DY.

Vet Parasitol. 2003 Mar 25;112(4):269-76.

PMID:
12623206
5.

Trapoxin, an antitumor cyclic tetrapeptide, is an irreversible inhibitor of mammalian histone deacetylase.

Kijima M, Yoshida M, Sugita K, Horinouchi S, Beppu T.

J Biol Chem. 1993 Oct 25;268(30):22429-35.

6.

Depudecin: a novel compound inducing the flat phenotype of NIH3T3 cells doubly transformed by ras- and src-oncogene, produced by Alternaria brassicicola.

Matsumoto M, Matsutani S, Sugita K, Yoshida H, Hayashi F, Terui Y, Nakai H, Uotani N, Kawamura Y, Matsumoto K, et al.

J Antibiot (Tokyo). 1992 Jun;45(6):879-85.

7.

Biosynthesis and role in virulence of the histone deacetylase inhibitor depudecin from Alternaria brassicicola.

Wight WD, Kim KH, Lawrence CB, Walton JD.

Mol Plant Microbe Interact. 2009 Oct;22(10):1258-67. doi: 10.1094/MPMI-22-10-1258.

8.

Depudecin, a microbial metabolite containing two epoxide groups, exhibits anti-angiogenic activity in vivo.

Oikawa T, Onozawa C, Inose M, Sasaki M.

Biol Pharm Bull. 1995 Sep;18(9):1305-7.

PMID:
8845831
9.

Histone deacetylase as a new target for cancer chemotherapy.

Yoshida M, Furumai R, Nishiyama M, Komatsu Y, Nishino N, Horinouchi S.

Cancer Chemother Pharmacol. 2001 Aug;48 Suppl 1:S20-6. Review.

PMID:
11587361
10.

Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells.

Marks PA, Richon VM, Rifkind RA.

J Natl Cancer Inst. 2000 Aug 2;92(15):1210-6. Review.

PMID:
10922406
11.

Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin.

Furumai R, Komatsu Y, Nishino N, Khochbin S, Yoshida M, Horinouchi S.

Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):87-92.

12.

Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation.

Park JH, Jung Y, Kim TY, Kim SG, Jong HS, Lee JW, Kim DK, Lee JS, Kim NK, Kim TY, Bang YJ.

Clin Cancer Res. 2004 Aug 1;10(15):5271-81.

13.

MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo.

Fournel M, Bonfils C, Hou Y, Yan PT, Trachy-Bourget MC, Kalita A, Liu J, Lu AH, Zhou NZ, Robert MF, Gillespie J, Wang JJ, Ste-Croix H, Rahil J, Lefebvre S, Moradei O, Delorme D, Macleod AR, Besterman JM, Li Z.

Mol Cancer Ther. 2008 Apr;7(4):759-68. doi: 10.1158/1535-7163.MCT-07-2026.

14.

Histone hyperacetylation induced by histone deacetylase inhibitors is not sufficient to cause growth inhibition in human dermal fibroblasts.

Brinkmann H, Dahler AL, Popa C, Serewko MM, Parsons PG, Gabrielli BG, Burgess AJ, Saunders NA.

J Biol Chem. 2001 Jun 22;276(25):22491-9. Epub 2001 Apr 13.

15.

Apicidin, an inhibitor of histone deacetylase, prevents H-ras-induced invasive phenotype.

Kim MS, Son MW, Kim WB, In Park Y, Moon A.

Cancer Lett. 2000 Aug 31;157(1):23-30.

PMID:
10893438
16.

Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin.

Han JW, Ahn SH, Park SH, Wang SY, Bae GU, Seo DW, Kwon HK, Hong S, Lee HY, Lee YW, Lee HW.

Cancer Res. 2000 Nov 1;60(21):6068-74.

17.
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20.

Inhibitors of histone deacetylase as new anticancer agents.

Jung M.

Curr Med Chem. 2001 Oct;8(12):1505-11. Review.

PMID:
11562279

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