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The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases.

Mitchell P, Petfalski E, Shevchenko A, Mann M, Tollervey D.

Cell. 1997 Nov 14;91(4):457-66.


The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism.

Mitchell P, Petfalski E, Tollervey D.

Genes Dev. 1996 Feb 15;10(4):502-13.


A single subunit, Dis3, is essentially responsible for yeast exosome core activity.

Dziembowski A, Lorentzen E, Conti E, Séraphin B.

Nat Struct Mol Biol. 2007 Jan;14(1):15-22. Epub 2006 Dec 17.


Reconstitution, activities, and structure of the eukaryotic RNA exosome.

Liu Q, Greimann JC, Lima CD.

Cell. 2006 Dec 15;127(6):1223-37. Erratum in: Cell. 2007 Oct 5;131(1):188-9.


The exosome of Trypanosoma brucei.

Estévez AM, Kempf T, Clayton C.

EMBO J. 2001 Jul 16;20(14):3831-9.


Nop53p interacts with 5.8S rRNA co-transcriptionally, and regulates processing of pre-rRNA by the exosome.

Granato DC, Machado-Santelli GM, Oliveira CC.

FEBS J. 2008 Aug;275(16):4164-78. doi: 10.1111/j.1742-4658.2008.06565.x. Epub 2008 Jul 9.


Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p.

Xue Y, Bai X, Lee I, Kallstrom G, Ho J, Brown J, Stevens A, Johnson AW.

Mol Cell Biol. 2000 Jun;20(11):4006-15.


Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.

Callahan KP, Butler JS.

Nucleic Acids Res. 2008 Dec;36(21):6645-55. doi: 10.1093/nar/gkn743. Epub 2008 Oct 21.


Probing genuine strong interactions and post-translational modifications in the heterogeneous yeast exosome protein complex.

Synowsky SA, van den Heuvel RH, Mohammed S, Pijnappel PW, Heck AJ.

Mol Cell Proteomics. 2006 Sep;5(9):1581-92. Epub 2006 Jul 7.


Human dis3p, which binds to either GTP- or GDP-Ran, complements Saccharomyces cerevisiae dis3.

Shiomi T, Fukushima K, Suzuki N, Nakashima N, Noguchi E, Nishimoto T.

J Biochem. 1998 May;123(5):883-90. Erratum in: J Biochem (Tokyo) 1998 Jul;124(1):250.


The exosome subunit Rrp44 plays a direct role in RNA substrate recognition.

Schneider C, Anderson JT, Tollervey D.

Mol Cell. 2007 Jul 20;27(2):324-31.


The archaeal exosome core is a hexameric ring structure with three catalytic subunits.

Lorentzen E, Walter P, Fribourg S, Evguenieva-Hackenberg E, Klug G, Conti E.

Nat Struct Mol Biol. 2005 Jul;12(7):575-81. Epub 2005 Jun 12.


Functional link between the mammalian exosome and mRNA decapping.

Wang Z, Kiledjian M.

Cell. 2001 Dec 14;107(6):751-62.


The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L.

Tomecki R, Kristiansen MS, Lykke-Andersen S, Chlebowski A, Larsen KM, Szczesny RJ, Drazkowska K, Pastula A, Andersen JS, Stepien PP, Dziembowski A, Jensen TH.

EMBO J. 2010 Jul 21;29(14):2342-57. doi: 10.1038/emboj.2010.121. Epub 2010 Jun 8.


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