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Items: 1 to 20 of 176

1.

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2.

Shieh SY, Ikeda M, Taya Y, Prives C.

Cell. 1997 Oct 31;91(3):325-34.

2.

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.

Maya R, Balass M, Kim ST, Shkedy D, Leal JF, Shifman O, Moas M, Buschmann T, Ronai Z, Shiloh Y, Kastan MB, Katzir E, Oren M.

Genes Dev. 2001 May 1;15(9):1067-77.

4.

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage.

Khosravi R, Maya R, Gottlieb T, Oren M, Shiloh Y, Shkedy D.

Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14973-7.

5.
6.

HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage.

Pääjärvi G, Roudier E, Crisby M, Högberg J, Stenius U.

FASEB J. 2005 Mar;19(3):476-8. Epub 2004 Dec 29.

PMID:
15625077
7.
8.

Mdm-2 phosphorylation by DNA-dependent protein kinase prevents interaction with p53.

Mayo LD, Turchi JJ, Berberich SJ.

Cancer Res. 1997 Nov 15;57(22):5013-6.

10.

Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation.

Goldberg Z, Vogt Sionov R, Berger M, Zwang Y, Perets R, Van Etten RA, Oren M, Taya Y, Haupt Y.

EMBO J. 2002 Jul 15;21(14):3715-27.

11.

Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage.

Chehab NH, Malikzay A, Stavridi ES, Halazonetis TD.

Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13777-82.

12.
13.

Functional role of Mdm2 phosphorylation by ATR in attenuation of p53 nuclear export.

Shinozaki T, Nota A, Taya Y, Okamoto K.

Oncogene. 2003 Dec 4;22(55):8870-80.

PMID:
14654783
14.

p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK.

Boehme KA, Kulikov R, Blattner C.

Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7785-90. doi: 10.1073/pnas.0703423105. Epub 2008 May 27.

15.

Mdm2 association with p53 targets its ubiquitination.

Fuchs SY, Adler V, Buschmann T, Wu X, Ronai Z.

Oncogene. 1998 Nov 12;17(19):2543-7.

16.

Constitutive mdmx expression during cell growth, differentiation, and DNA damage.

Jackson MW, Berberich SJ.

DNA Cell Biol. 1999 Sep;18(9):693-700.

PMID:
10492400
17.

The promyelocytic leukemia protein protects p53 from Mdm2-mediated inhibition and degradation.

Louria-Hayon I, Grossman T, Sionov RV, Alsheich O, Pandolfi PP, Haupt Y.

J Biol Chem. 2003 Aug 29;278(35):33134-41. Epub 2003 Jun 16.

18.

The carboxy-terminal serine 392 phosphorylation site of human p53 is not required for wild-type activities.

Fiscella M, Zambrano N, Ullrich SJ, Unger T, Lin D, Cho B, Mercer WE, Anderson CW, Appella E.

Oncogene. 1994 Nov;9(11):3249-57.

PMID:
7936649
19.

Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified.

Mayo LD, Seo YR, Jackson MW, Smith ML, Rivera Guzman J, Korgaonkar CK, Donner DB.

J Biol Chem. 2005 Jul 15;280(28):25953-9. Epub 2005 Apr 20.

20.

Phosphorylation of murine double minute clone 2 (MDM2) protein at serine-267 by protein kinase CK2 in vitro and in cultured cells.

Hjerrild M, Milne D, Dumaz N, Hay T, Issinger OG, Meek D.

Biochem J. 2001 Apr 15;355(Pt 2):347-56.

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