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Items: 1 to 20 of 110

1.
4.

[Dihydropyrimidine déhydrogenase (DPD) deficiency screening and securing of fluoropyrimidine-based chemotherapies: Update and recommendations of the French GPCO-Unicancer and RNPGx networks].

Loriot MA, Ciccolini J, Thomas F, Barin-Le-Guellec C, Royer B, Milano G, Picard N, Becquemont L, Verstuyft C, Narjoz C, Schmitt A, Bobin-Dubigeon C, Harle A, Paci A, Poinsignon V, Quaranta S, Evrard A, Hennart B, Broly F, Fonrose X, Lafay-Chebassier C, Wozny AS, Masskouri F, Boyer JC, Etienne-Grimaldi MC.

Bull Cancer. 2018 Apr;105(4):397-407. doi: 10.1016/j.bulcan.2018.02.001. Epub 2018 Feb 24. Review. French.

5.

Rapid identification of dihydropyrimidine dehydrogenase deficiency by using a novel 2-13C-uracil breath test.

Mattison LK, Ezzeldin H, Carpenter M, Modak A, Johnson MR, Diasio RB.

Clin Cancer Res. 2004 Apr 15;10(8):2652-8.

6.

High-performance liquid chromatographic assay with ultraviolet detection for quantification of dihydrofluorouracil in human lymphocytes: application to measurement of dihydropyrimidine dehydrogenase activity.

Déporte-Féty R, Picot M, Amiand M, Moreau A, Campion L, Lanoë D, Renée N, Milano G.

J Chromatogr B Biomed Sci Appl. 2001 Oct 25;762(2):203-9.

PMID:
11678380
8.

Dihydropyrimidine dehydrogenase deficiency and fluorouracil-related toxicity.

Milano G, Etienne MC, Pierrefite V, Barberi-Heyob M, Deporte-Fety R, Renée N.

Br J Cancer. 1999 Feb;79(3-4):627-30.

9.

Putative role of dihydropyrimidine dehydrogenase in the toxic side effect of 5-fluorouracil in colorectal cancer patients.

Katona C, Kralovánszky J, Rosta A, Pandi E, Fónyad G, Tóth K, Jeney A.

Oncology. 1998 Sep-Oct;55(5):468-74.

PMID:
9732227
10.

The effect of dihydropyrimidine dehydrogenase deficiency on outcomes with fluorouracil.

Gardiner SJ, Begg EJ, Robinson BA.

Adverse Drug React Toxicol Rev. 2002;21(1-2):1-16. Review.

PMID:
12140902
11.

Life-threatening toxicity in a dihydropyrimidine dehydrogenase-deficient patient after treatment with topical 5-fluorouracil.

Johnson MR, Hageboutros A, Wang K, High L, Smith JB, Diasio RB.

Clin Cancer Res. 1999 Aug;5(8):2006-11.

12.

Delayed hypersensitivity to 5-fluorouracil associated with reduced dihydropyrimidine dehydrogenase (DPD) activity.

Duley JA, Nethersell AB.

Adv Exp Med Biol. 1998;431:147-50. No abstract available.

PMID:
9598048
13.

Individualizing therapy with 5-fluorouracil related to dihydropyrimidine dehydrogenase: theory and limits.

Milano G, Etienne MC.

Ther Drug Monit. 1996 Aug;18(4):335-40. Review.

PMID:
8857547
14.

Relationship between 5-fluorouracil disposition, toxicity and dihydropyrimidine dehydrogenase activity in cancer patients.

Di Paolo A, Danesi R, Falcone A, Cionini L, Vannozzi F, Masi G, Allegrini G, Mini E, Bocci G, Conte PF, Del Tacca M.

Ann Oncol. 2001 Sep;12(9):1301-6.

PMID:
11697844
15.

High-throughput genotyping by DHPLC of the dihydropyrimidine dehydrogenase gene implicated in (fluoro)pyrimidine catabolism.

Gross E, Seck K, Neubauer S, Mayr J, Hellebrand H, Ratanaphan A, Lutz V, Stockinger H, Kiechle M.

Int J Oncol. 2003 Feb;22(2):325-32.

PMID:
12527930
16.

Dihydropyrimidine dehydrogenase activity in cancer patients.

Fleming RA, Milano GA, Gaspard MH, Bargnoux PJ, Thyss A, Plagne R, Renée N, Schneider M, Demard F.

Eur J Cancer. 1993;29A(5):740-4.

PMID:
8471333
18.

Severe fluoropyrimidine toxicity due to novel and rare DPYD missense mutations, deletion and genomic amplification affecting DPD activity and mRNA splicing.

van Kuilenburg AB, Meijer J, Maurer D, Dobritzsch D, Meinsma R, Los M, Knegt LC, Zoetekouw L, Jansen RL, Dezentjé V, van Huis-Tanja LH, van Kampen RJ, Hertz JM, Hennekam RC.

Biochim Biophys Acta Mol Basis Dis. 2017 Mar;1863(3):721-730. doi: 10.1016/j.bbadis.2016.12.010. Epub 2016 Dec 24.

19.

A rapid and inexpensive method for anticipating severe toxicity to fluorouracil and fluorouracil-based chemotherapy.

Ciccolini J, Mercier C, Evrard A, Dahan L, Boyer JC, Duffaud F, Richard K, Blanquicett C, Milano G, Blesius A, Durand A, Seitz JF, Favre R, Lacarelle B.

Ther Drug Monit. 2006 Oct;28(5):678-85.

PMID:
17038885
20.

Pitfalls in the diagnosis of patients with a partial dihydropyrimidine dehydrogenase deficiency.

Van Kuilenburg AB, Van Lenthe H, Tromp A, Veltman PC, Van Gennip AH.

Clin Chem. 2000 Jan;46(1):9-17.

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