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Items: 1 to 20 of 105

1.

Characterization of murine Flt4 ligand/VEGF-C.

Fitz LJ, Morris JC, Towler P, Long A, Burgess P, Greco R, Wang J, Gassaway R, Nickbarg E, Kovacic S, Ciarletta A, Giannotti J, Finnerty H, Zollner R, Beier DR, Leak LV, Turner KJ, Wood CR.

Oncogene. 1997 Jul 31;15(5):613-8.

2.

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.

Joukov V, Pajusola K, Kaipainen A, Chilov D, Lahtinen I, Kukk E, Saksela O, Kalkkinen N, Alitalo K.

EMBO J. 1996 Jan 15;15(2):290-98. Erratum in: EMBO J. 1996 Apr 1;15(7):1751.

3.

Signalling properties of FLT4, a proteolytically processed receptor tyrosine kinase related to two VEGF receptors.

Pajusola K, Aprelikova O, Pelicci G, Weich H, Claesson-Welsh L, Alitalo K.

Oncogene. 1994 Dec;9(12):3545-55.

PMID:
7970715
4.

Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4.

Lee J, Gray A, Yuan J, Luoh SM, Avraham H, Wood WI.

Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):1988-92.

5.

VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development.

Kukk E, Lymboussaki A, Taira S, Kaipainen A, Jeltsch M, Joukov V, Alitalo K.

Development. 1996 Dec;122(12):3829-37.

6.

Biochemical characterization of two isoforms of FLT4, a VEGF receptor-related tyrosine kinase.

Borg JP, deLapeyrière O, Noguchi T, Rottapel R, Dubreuil P, Birnbaum D.

Oncogene. 1995 Mar 2;10(5):973-84.

PMID:
7898938
7.

Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4).

Achen MG, Jeltsch M, Kukk E, Mäkinen T, Vitali A, Wilks AF, Alitalo K, Stacker SA.

Proc Natl Acad Sci U S A. 1998 Jan 20;95(2):548-53.

8.

Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody.

Zhu Z, Lu D, Kotanides H, Santiago A, Jimenez X, Simcox T, Hicklin DJ, Bohlen P, Witte L.

Cancer Lett. 1999 Mar 1;136(2):203-13.

PMID:
10355750
9.

Avian VEGF-C: cloning, embryonic expression pattern and stimulation of the differentiation of VEGFR2-expressing endothelial cell precursors.

Eichmann A, Corbel C, Jaffredo T, Bréant C, Joukov V, Kumar V, Alitalo K, le Douarin NM.

Development. 1998 Feb;125(4):743-52.

10.

The FLT4 gene encodes a transmembrane tyrosine kinase related to the vascular endothelial growth factor receptor.

Galland F, Karamysheva A, Pebusque MJ, Borg JP, Rottapel R, Dubreuil P, Rosnet O, Birnbaum D.

Oncogene. 1993 May;8(5):1233-40.

PMID:
8386825
11.

Mutation at tyrosine residue 1337 abrogates ligand-dependent transforming capacity of the FLT4 receptor.

Fournier E, Dubreuil P, Birnbaum D, Borg JP.

Oncogene. 1995 Sep 7;11(5):921-31.

PMID:
7675451
12.

A mutant form of vascular endothelial growth factor (VEGF) that lacks VEGF receptor-2 activation retains the ability to induce vascular permeability.

Stacker SA, Vitali A, Caesar C, Domagala T, Groenen LC, Nice E, Achen MG, Wilks AF.

J Biol Chem. 1999 Dec 3;274(49):34884-92.

13.

FLT4 receptor tyrosine kinase contains seven immunoglobulin-like loops and is expressed in multiple human tissues and cell lines.

Pajusola K, Aprelikova O, Korhonen J, Kaipainen A, Pertovaara L, Alitalo R, Alitalo K.

Cancer Res. 1992 Oct 15;52(20):5738-43. Erratum in: Cancer Res 1993 Aug 15;53(16):3845.

15.
16.

Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema.

Karkkainen MJ, Ferrell RE, Lawrence EC, Kimak MA, Levinson KL, McTigue MA, Alitalo K, Finegold DN.

Nat Genet. 2000 Jun;25(2):153-9.

PMID:
10835628
17.

Characterization of a soluble vascular endothelial growth factor receptor-immunoglobulin chimera.

Kaplan JB, Sridharan L, Zaccardi JA, Dougher-Vermazen M, Terman BI.

Growth Factors. 1997;14(4):243-56.

PMID:
9386989
18.

Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.

Kaipainen A, Korhonen J, Mustonen T, van Hinsbergh VW, Fang GH, Dumont D, Breitman M, Alitalo K.

Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3566-70.

19.

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