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Items: 1 to 20 of 415

1.

A family of cytokine-inducible inhibitors of signalling.

Starr R, Willson TA, Viney EM, Murray LJ, Rayner JR, Jenkins BJ, Gonda TJ, Alexander WS, Metcalf D, Nicola NA, Hilton DJ.

Nature. 1997 Jun 26;387(6636):917-21.

PMID:
9202125
2.

Structure and function of a new STAT-induced STAT inhibitor.

Naka T, Narazaki M, Hirata M, Matsumoto T, Minamoto S, Aono A, Nishimoto N, Kajita T, Taga T, Yoshizaki K, Akira S, Kishimoto T.

Nature. 1997 Jun 26;387(6636):924-9.

PMID:
9202127
3.

A new protein containing an SH2 domain that inhibits JAK kinases.

Endo TA, Masuhara M, Yokouchi M, Suzuki R, Sakamoto H, Mitsui K, Matsumoto A, Tanimura S, Ohtsubo M, Misawa H, Miyazaki T, Leonor N, Taniguchi T, Fujita T, Kanakura Y, Komiya S, Yoshimura A.

Nature. 1997 Jun 26;387(6636):921-4.

PMID:
9202126
4.

Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction.

Nicholson SE, Willson TA, Farley A, Starr R, Zhang JG, Baca M, Alexander WS, Metcalf D, Hilton DJ, Nicola NA.

EMBO J. 1999 Jan 15;18(2):375-85.

5.

Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling.

Pezet A, Favre H, Kelly PA, Edery M.

J Biol Chem. 1999 Aug 27;274(35):24497-502.

6.

Induction of JAB/SOCS-1/SSI-1 and CIS3/SOCS-3/SSI-3 is involved in gp130 resistance in cardiovascular system in rat treated with cardiotrophin-1 in vivo.

Hamanaka I, Saito Y, Yasukawa H, Kishimoto I, Kuwahara K, Miyamoto Y, Harada M, Ogawa E, Kajiyama N, Takahashi N, Izumi T, Kawakami R, Masuda I, Yoshimura A, Nakao K.

Circ Res. 2001 Apr 13;88(7):727-32.

7.

Suppressors of cytokine signalling: SOCS.

Larsen L, Röpke C.

APMIS. 2002 Dec;110(12):833-44. Review.

PMID:
12645661
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12.

Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling.

Narazaki M, Fujimoto M, Matsumoto T, Morita Y, Saito H, Kajita T, Yoshizaki K, Naka T, Kishimoto T.

Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13130-4.

13.

The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling.

Fischer P, Lehmann U, Sobota RM, Schmitz J, Niemand C, Linnemann S, Haan S, Behrmann I, Yoshimura A, Johnston JA, Müller-Newen G, Heinrich PC, Schaper F.

Biochem J. 2004 Mar 1;378(Pt 2):449-60.

15.

Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells.

Baetz A, Frey M, Heeg K, Dalpke AH.

J Biol Chem. 2004 Dec 24;279(52):54708-15. Epub 2004 Oct 18.

16.

SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130.

Schmitz J, Weissenbach M, Haan S, Heinrich PC, Schaper F.

J Biol Chem. 2000 Apr 28;275(17):12848-56.

17.

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway.

Heinrich PC, Behrmann I, Müller-Newen G, Schaper F, Graeve L.

Biochem J. 1998 Sep 1;334 ( Pt 2):297-314. Review.

18.

The JAK-inhibitor, JAB/SOCS-1 selectively inhibits cytokine-induced, but not v-Src induced JAK-STAT activation.

Iwamoto T, Senga T, Naito Y, Matsuda S, Miyake Y, Yoshimura A, Hamaguchi M.

Oncogene. 2000 Sep 28;19(41):4795-801.

19.

Cytokine-induced Src homology 2 protein (CIS) promotes T cell receptor-mediated proliferation and prolongs survival of activated T cells.

Li S, Chen S, Xu X, Sundstedt A, Paulsson KM, Anderson P, Karlsson S, Sjögren HO, Wang P.

J Exp Med. 2000 Mar 20;191(6):985-94.

20.

Twenty proteins containing a C-terminal SOCS box form five structural classes.

Hilton DJ, Richardson RT, Alexander WS, Viney EM, Willson TA, Sprigg NS, Starr R, Nicholson SE, Metcalf D, Nicola NA.

Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):114-9.

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